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抑制剂&激动剂
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  • 抑制剂&激动剂
    8
    TargetMol | Inhibitors_Agonists
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    TargetMol | PROTAC
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    TargetMol | Inhibitors_Agonists
  • Etofenamate
    依托芬那酯
    T255330544-47-9
    Etofenamate 是非甾体类抗炎小分子,也是非选择性的 COX 抑制剂,具有抗风湿和解热抗炎作用,可用于缓解疼痛、关节炎等炎症相关疾病的研究。
    • ¥ 197
    In stock
    规格
    数量
  • (S)-Thalidomide
    (S)-沙利度胺, (S)-(-)-Thalidomide
    T12644L841-67-8In house
    (S)-Thalidomide ((S)-(-)-Thalidomide) 是 Thalidomide 的 S 型异构体,具有免疫调节,抗炎,抗癌,抗血管生成活性和促凋亡活性,可用于研究麻风结节性红斑和骨髓瘤。
    • ¥ 248
    In stock
    规格
    数量
  • 3-Hydroxykynurenamine
    T6818299362-47-7In house
    3-Hydroxykynurenamine, also known as 3-Hydroxy-L-kynurenamine or 3-HKA, is a biogenic amine produced via an alternative pathway of tryptophan metabolism. In vitro, 3-HKA has an anti-inflammatory profile by inhibiting the IFN-γ mediated STAT1 NF-κΒ pathway in both mouse and human dendritic cells (DCs) with a consequent decrease in the release of pro-inflammatory chemokines and cytokines, most notably TNF, IL-6, and IL12p70. 3-HKA has protective effects in an experimental mouse model of psoriasis by decreasing skin thickness, erythema, scaling and fissuring, reducing TNF, IL-1β, IFN-γ, and IL-17 production, and inhibiting generation of effector CD8+ T cells. Similarly, in a mouse model of nephrotoxic nephritis, besides reducing inflammatory cytokines, 3-HKA improves proteinuria and serum urea nitrogen, overall ameliorating immune-mediated glomerulonephritis and renal dysfunction.This compound is unstable in powder form and other related salt forms are recommended.
    • ¥ 10600
    3-6月
    规格
    数量
  • Funapide
    TV 45070, XEN402
    T153581259933-16-8
    Funapide (TV 45070) 是一个有效的钠通 Nav1.7 抑制剂,据有潜在的抗炎活性,可用来治疗红斑性肢痛症、肌肉骨骼疼痛、膝关节炎以及疱疹后神经。
    • ¥ 1490
    In stock
    规格
    数量
  • Furfuryl tetrahydropyranyladenine
    PRK-124, PRK124, PRK 124
    T202786109403-64-7
    Furfuryl tetrahydropyranyladenine在治疗红斑痤疮方面表现出疗效。
    • 待询
    10-14周
    规格
    数量
  • Halobetasol propionate
    卤贝他索丙酸酯, 卤倍他索丙酸酯, Halobetasol Propionate, Ulobetasol propionate, BMY-30056, CGP-14458
    T652966852-54-8
    Halobetasol propionate (BMY-30056) 是一种在皮肤外使用的合成类固醇,具有抗炎,止痒和收缩血管的活性。
    • ¥ 133
    In stock
    规格
    数量
  • Indomethacin salicylate
    T6892665474-39-7
    Indomethacin salicylate is an antiinflammatory drug. It has shown remarkable inhibitory effects on carrageenin edema, ultraviolet erythema and adjuvant arthritis.
    • ¥ 10600
    6-8周
    规格
    数量
  • Poloxamer 184 (L64)
    9003-11-6
    TSH-00414
    Poloxamer 184 L64 是由聚氧乙烯和聚氧丙烯形成的嵌段聚合物,平均分子量为2900。Poloxamer 184 L64 短期内对皮肤具有毒性,表现为轻微红斑和皮内炎症反应。此化合物具有抗菌活性,在1 mg mL浓度下可抑制60%的Mycobacterium avium。Poloxamer 184 L64 可以形成热可逆水凝胶,被用于食品添加剂,并作为药物输送载体在化妆品、药品和组织工程学中应用。
    • 待询
    5日内发货
    规格
    数量
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