2-((Azido-PEG8-carbamoyl)methoxy)acetic acid is a polyethylene glycol (PEG) derivative that serves as a linker for proteolysis targeting chimeras (PROTACs) synthesis [1].
(-)-Sitagliptin carbamoyl glucuronide is a minor phase II metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor (-)-sitagliptin . (-)-Sitagliptin carbamoyl glucuronide is formed by N-carbamoyl glucuronidation and has been found in rat and dog plasma following administration of (-)-sitagliptin.
Carbamoyl phosphate dilithium salt 在医药领域中作为一种有效的抗镰状化剂被广泛利用,具备调控尿素循环的关键性作用.在红细胞中,该化合物通过对血红蛋白 S 的氨基末端缬氨酸残基进行氨基甲酰化作用,进而阻断镰状化进程.此外,由于含有锂阳离子,Carbamoyl phosphate dilithium salt 也表现出一定的毒性.
N-Carbamoyl-L-aspartic acid, an intermediate in pyrimidine metabolism, can be utilized to measure the enzyme activity of dihydroorotase (DHOse) [1] [2].
Descarbamoyl cefuroxime is also an intermediate in the synthesis of cephalosporin antibiotics. Decarbamyl cefuroxime is a degradation product of cefuroxime.
Bromoacetamido-PEG9-ethylcarbamoyl-C12-Boc is a polyethylene glycol (PEG) derived linker employed for synthesizing proteolysis-targeting chimeras (PROTACs)[1].