azido-peg-1-azide

Azido-PEG1-azide 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。

Azido-PEG3-SS-PEG3-azide is a polyethylene glycol (PEG) based linker commonly employed in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Azido-PEG4-CH2-Boc is a four-unit cleavable polyethylene glycol (PEG) linker compound employed in the synthesis of antibody-drug conjugates (ADCs)[1] and PROTACs[2]. This linker is characterized by its azide functional group and PEG backbone, facilitating the conjugation of drugs to antibodies in ADC development and enabling the synthesis of PROTACs utilizing PEG and alkyl ether moieties.

m-PEG4-azide, also referred to as 13-Azido-2,5,8,11-tetraoxatridecane, functions as a PEG-based PROTAC linker suitable for PROTACs synthesis[1].

N-(Azido-PEG3)-N-Boc-PEG4-acid is a PEG-based PROTAC linker featuring a terminal azide group, primarily employed in PROTAC synthesis[1].

N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a PEG-based PROTAC linker featuring a terminal azide group. It is commonly employed in the synthesis of PROTACs[1].

Azido-PEG3-S-PEG3-azide is a polyethylene glycol (PEG)-derived linker specifically designed for the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Azido-PEG3-S-PEG4-propargyl is a polyethylene glycol (PEG)-based linker that contains the azide group and propargyl functionality. This linker is designed specifically for the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Azido-PEG3-SS-NHS is a three-unit polyethylene glycol (PEG) linker functionalized with an azide group, a cleavable disulfide bond, and an N-hydroxysuccinimide ester. It is primarily employed in the synthesis of antibody-drug conjugates (ADCs) [1].

Azido-PEG6-azide, a PEG-based PROTAC linker, is used in the synthesis of PROTACs [1].

N-Methyl-N'-(azido-PEG2-C5)-Cy5 is a polyethylene glycol (PEG)-based linker that incorporates an azide functionality. This linker is primarily utilized in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Bocaminooxyacetamide-PEG2-Azido 是一种可降解的含2个单元PEG的ADC linker，可用于合成抗体偶联活性分子 (ADC)。作为点击化学试剂，它含有Azide基团，可以与含Alkyne基团的分子进行铜催化叠氮-炔环加成反应（CuAAc），也可以与含DBCO或BCN基团的分子进行菌株促进的炔-叠氮环加成反应 (SPAAC)。

Azido-PEG1-Val-Cit-PABC-PNP，这是一种结构包含单个PEG单元的ADC linker，它适用于抗体偶联活性分子（ADC）的合成。此化合物也是点击化学试剂，含有Azide基团，能通过铜催化的叠氮-炔环加成反应（CuAAc）与Alkyne基团的分子反应。同时，它也可以通过菌株促进的炔-叠氮环加成反应（SPAAC）与DBCO或BCN基团的分子进行反应。