amphotericin b

Amphotericin B (NSC-527017) 是一种多烯类抗真菌剂，对许多真菌物种具有广谱活性。Amphotericin B 不可逆地结合麦角甾醇，破坏细胞膜完整性，从而起到抗真菌活性。

Amphotericin B methyl ester is the derivative of the antibiotic Amphotericin B. Amphotericin B methyl ester is the cholesterol-binding compound that possesses significant antifungal activity. It disrupts HIV-1 particle production and potently inhibits HIV

Amphotericin B methyl ester hydrochloride 是多烯类抗生素 Amphotericin B (A634250) 的甲酯衍生物。Amphotericin B methyl ester hydrochloride 是胆固醇结合物，具有显著的抗真菌活性。Amphotericin B methyl ester hydrochloride 干扰HIV-1颗粒的产生，抑制HIV-1的复制。

Amphotericin B trihydrate, a polyene antibiotic, is derived from Streptomyces nodosus fermenter cultures. It exhibits antileishmanial properties.

L-Citronellol ((S)-(-)-beta-Citronellol) 是一种从天竺葵中分离到的小分子化合物，具有抗真菌活性， 会对真菌膜产生影响。L-Citronellol 在对念珠菌酵母菌作用时与两性霉素B具有协同作用。

Heat shock protein (Hsp) inhibitor II is the active form of Hsp inhibitor I and a benzylidene lactam compound that prevents the synthesis of inducible Hsps, such as Hsp105, Hsp72, and Hsp40. Hsp inhibitor II decreases Hsp72 synthesis in vivo and reduces thermotolerance of tumors in SCC VII tumor-containing mice. At 100 μM, it inhibits the development of thermotolerance in COLO 320 DM cells. Inhibition of Hsp70 with Hsp inhibitor II in combination with amphotericin B increases susceptibility of AmB-susceptible (MICs = 0.058 versus 0.27 μg ml for combined and AmB alone, respectively) and AmB-resistant (MICs = 21.33 versus >32 μg ml for combined and AmB alone, respectively) strains of A. fumigatus.

Amphocil is used to treat patients with invasive fungal infection.

Amphotericin B Methyl Ester 的氘代化合物。Amphotericin B Methyl Ester的 CAS 号为 36148-89-7。Amphotericin B Methyl Ester 是抗生素 Amphotericin B 的衍生物，是一种具有显著抗真菌活性的胆固醇结合化合物

Amphotericin X1 is a derivative of Amphotericin B with good antifungal activity. Amphotericin X1 inhibits Candida albicans 33 079, Cryptococcus neoformans 451, C.parapsilosis 937A, Aspergillus niger 57A and A.fumigatus (MICs: 1 μg mL, 1 μg mL, 8 μg mL, 2

MS 8209 is an amphotericin B derivative has effects on on tumor necrosis factor alpha synthesis and human immunodeficiency virus replication in macrophages.