allergen

Rosin 分离自松木或松树桩中，是一种频繁接触的过敏原，能够导致过敏性接触性皮炎。

Allergen Gal d 4 (46-61), chicken, is a peptide derived from hen egg white lysozyme.

ZD-2138是一种有效且具有选择性的5-脂氧合酶（5-LOX）的特异性抑制剂，抑制了过敏原诱导的肺支气管收缩，可减少豚鼠孤立气道的神经诱发性快速激肽能收缩。ZD-2138可用来治疗哮喘疾病。

S-Y048 是一种 Oxoeicosanoid（OXE）受体拮抗剂，抑制过敏原诱导的嗜酸性粒细胞浸润到实验中对屋尘螨敏感的恒河猴皮肤，抑制因雾化过敏原攻击引起的肺部炎症。S-Y048 可用于研究哮喘和其他嗜酸性粒细胞性疾病。

Ethylparaben (Ethyl parahydroxybenzoate) 是一种标准化的化学过敏原。 对羟基苯甲酸乙酯的生理作用是通过增加组胺释放和细胞介导免疫来实现的。

Chlorquinaldol (5,7-Dichloro-8-hydroxy-2-methylquinoline) 是一种抗菌剂, 有潜力研究局部皮肤病症和阴道感染。

Butylparaben (Butyl 4-hydroxybenzoate) 是一种标准化的化学过敏原，可增加组胺释放和细胞介导的免疫。

Eugenol (Allylguaiacol) 是一种从丁香中发现的精油，抑制脂质的过氧化，具有抗菌，驱虫和抗氧化活性。

Tulipalin A (α-methylene-γ-butyrolactone) 是来源于郁金香鳞茎的有毒糖苷。Tulipalin A 是引起过敏性接触皮炎的致敏性致敏物 (causative allergen)，在低剂量影响免疫细胞的功能，例如 Jurkat T 细胞。

GSK2245035 is a highly selective intranasal TLR7 agonist with preferential Type-1 interferon (IFN)-stimulating properties (pEC50s: 9.3 and 6.5 for IFNα and TFNα). It effectively suppresses allergen-induced Th2 cytokine production in human peripheral blood

AZD5423 是可吸入的非甾体糖皮质激素受体选择性调节剂，能够有效降改善轻度过敏性哮喘患者的过敏原诱导反应。

1,4-Phenylenediamine-15N2 是一种15N2标记的1,4-Phenylenediamine。1,4-Phenylenediamine 可作为合成复合材料的分子构件，并且是染发剂中的成分，还是一种可能的皮肤过敏原。

BADGE 是一种标准化的化学过敏原。它的生理作用是通过增加组胺释放和细胞介导的免疫来实现的。

(±)12(13)-DiHOME is the diol form of (±)12(13)-EpOME , a cytochrome P450-derived epoxide of linoleic acid also known as isoleukotoxin. [1] It is formed from 12(13)-EpOME by soluble epoxide hydrolase (sEH) in neutrophils. [2] 12(13)-DiHOME is toxic to Sf21 cells expressing sEH and to lacZ-expressing control cells, unlike isoleukotoxin, which is only toxic to cells containing sEH.[1] [2] Levels of 12(13)-DiHOME are increased in rat spinal cord following burn injury, and it enhances cold tolerance, increases fatty acid uptake into brown adipocytes, and decreases serum triglyceride levels in mice. Levels are also elevated in bronchoalveolar lavage fluid (BALF) in humans following exposure to biodiesel exhaust and in exhaled breath condensate in patients with allergic asthma following allergen exposure.[5] [6] Plasma levels of 12(13)-DiHOME are increased immediately following moderate-intensity exercise in mice and humans, an effect that can be prevented by brown adipose tissue removal in the mouse.[7]

Olcorolimus inhibits single allergen-induced allergic inflammation such as eosinophilic and lymphocytic infiltration and mRNA expression for interleukin (IL)-4 and IL-5

Palmitoyl tripeptide-8，一种生物活性肽，具抗敏感功能，常作为化妆品成分应用。

Mevlonlerbart是针对Felcat allergen 1的特异性IgG4κ类抗体。Felcat allergen 1为一过敏原蛋白。

Freneslerbart为针对Felcat allergen 1的IgG4κ类抗体，后者为一过敏原蛋白。

Bremzalerbart为针对主要桦树花粉过敏原Bet v 1-A的BETVIA的人源IgG4单克隆抗体。

Atisnolerbart为一种靶向BETVIA的人源IgG4抗体，其中BETVIA指的是桦树花粉过敏原Bet v 1-A的主要成分。

3-Bromotyrosine, a product of protein oxidation, is generated after eosinophil activation during allergic responses. It serves as a biomarker for eosinophil peroxidase-induced protein oxidation both in vitro and in vivo. Beyond its association with eosinophils, 3-bromotyrosine levels are significantly elevated in peritoneal exudate from K. pneumoniae-infected mice, indicating a fivefold increase compared to uninfected controls, which implies that neutrophils may release increased levels of oxidized products during inflammation. Furthermore, in humans, allergen-challenged lung samples from patients with allergen-induced asthma show a tenfold increase in 3-bromotyrosine, highlighting its potential as a marker for oxidative stress in allergic conditions.

HYDAMTIQ 是一种 PARP-1 2 抑制剂 (IC50: 29-38 nM)，具有抗癌、抗炎和缺血保护作用。该化合物能够抑制肺部PARP活性，有效对抗由过敏原引起的咳嗽和呼吸困难，并减轻支气管对乙酰甲胆碱的高反应性。HYDAMTIQ 展现出广谱的抗癌活性，包括对卵巢癌、乳腺癌、前列腺癌、胰腺肿瘤以及多形性胶质母细胞瘤的抑制效果。在脑缺血、哮喘和多种癌症的动物模型中，HYDAMTIQ 已被证明具有体内效力。

Ethyl parahydroxybenzoate-d4 是 Ethyl parahydroxybenzoate 的氘代化合物。Ethyl parahydroxybenzoate 的 CAS 号为 120-47-8。Ethylparaben 是一种标准化的化学过敏原。 对羟基苯甲酸乙酯的生理作用是通过增加组胺释放和细胞介导免疫来实现的。

Eugenol-d3 是 Eugenol 的氘代化合物。Eugenol 的 CAS 号为 97-53-0。Eugenol是一种从丁香中发现的精油，抑制脂质的过氧化，具有抗菌，驱虫和抗氧化活性。