Acid-PEG1-C2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Acid-PEG3-C2-Boc is a compound used as a linker in the synthesis of PROTACs to facilitate the degradation of EGFR and the inhibition of mTOR[1][2]. It is classified as a PEG- and alkyl/ether-based PROTAC linker.
Acid-PEG4-C2-Boc is a linker compound based on polyethylene glycol (PEG) and alkyl/ether. It is utilized in the synthesis of PROteolysis TArgeting Chimeras (PROTACs) for the purpose of inhibiting the mechanistic Target of Rapamycin (mTOR)[1].
Boc-NH-PEG2-C2-amido-C4-acid (PROTAC Linker 30) is a polyethylene glycol (PEG)-based linker utilized for the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].