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Cat. No.	Product Name	Target	Signaling Pathways
T6676	Sofosbuvir 索非布韦,GS 7977,PSI-7977	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Sofosbuvir (GS 7977) 是一种丙型肝炎病毒聚合酶 NS5B 的尿苷单磷酸类似物抑制剂，用作治疗慢性丙型肝炎的抗病毒剂。
T12961	Sofosbuvir impurity F 索非布韦杂质 F,Sofosbuvir 3',5'-Bis-(S)-phosphate	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Sofosbuvir impurity F (Sofosbuvir 3',5'-Bis-(S)-phosphate) 既是 Sofosbuvir 的非对映异构体，也是 Sofosbuvir 的杂质，Sofosbuvir 是 HCV RNA 复制的抑制剂。
T12962	Sofosbuvir impurity G	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Sofosbuvir impurity G 是 Sofosbuvir 的非对映异构体，是 Sofosbuvir 的杂质。其中 Sofosbuvir 能够抑制 HCVRNA 的复制，具有抗丙型肝炎病毒作用。
T12954	Sofosbuvir 13CD3 GS-7977 13CD3,PSI-7977 13CD3	Others	Others
	Sofosbuvir 13CD3 is the deuterium labeled Sofosbuvir. Sofosbuvir is an active HCV RNA replication inhibitor in the HCV replicon assay, with potent anti-hepatitis C virus (HCV) activity.
T12960	Sofosbuvir impurity E	Others	Others
	Sofosbuvir impurity E is the less active impurity of Sofosbuvir. Sofosbuvir is an active HCV RNA replication inhibitor in the HCV replicon assay,with potent anti-hepatitis C virus (HCV) activity.
T12966	Sofosbuvir impurity K	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Sofosbuvir impurity K is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
T12959	Sofosbuvir impurity D	Others	Others
	Sofosbuvir impurity D is the less active impurity of Sofosbuvir. Sofosbuvir is an active HCV RNA replication inhibitor in the HCV replicon assay,with potent anti-hepatitis C virus (HCV) activity.
T12963	Sofosbuvir impurity H	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Sofosbuvir impurity H, an diastereoisomer of Sofosbuvir, is the impurity of Sofosbuvir. Sofosbuvir (PSI-7977) is a diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
T12958	Sofosbuvir impurity C	Others	Others
	Sofosbuvir impurity C is the less active impurity of Sofosbuvir. Sofosbuvir is an active HCV RNA replication inhibitor in the HCV replicon assay,with potent anti-hepatitis C virus (HCV) activity.
T12955	Sofosbuvir D6 PSI-7977 D6,GS-7977 D6	Others	Others
	Sofosbuvir D6 is the deuterium labeled Sofosbuvir. Sofosbuvir is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity.
T12957	Sofosbuvir impurity B	Others	Others
	Sofosbuvir impurity B is the less active impurity of Sofosbuvir. Sofosbuvir is an active HCV RNA replication inhibitor in the HCV replicon assay, with potent anti-hepatitis C virus (HCV) activity.
T12969	Sofosbuvir impurity N	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Sofosbuvir impurity N is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
T12965	Sofosbuvir impurity J	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Sofosbuvir impurity J is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
T12964	Sofosbuvir impurity I	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Sofosbuvir impurity I is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
T12967	Sofosbuvir impurity L	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Sofosbuvir impurity L is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
T12956	Sofosbuvir impurity A	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Sofosbuvir impurity A is an diastereoisomer of Sofosbuvir. Sofosbuvir is anHCV RNA replication inhibitor ,with potent anti-hepatitis C virus activity.
T11195	Enantiomer of Sofosbuvir	Others	Others
	Enantiomer of Sofosbuvir 是Sofosbuvir 的对映异构体，Sofosbuvir 是一种治疗慢性丙型肝炎的处方药，目前尚无enantiomer of Sofosbuvir 的生物活性报道。
T12968	Sofosbuvir impurity M	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Sofosbuvir impurity M is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
T12571	PSI-6206 13C,d3 Sofosbuvir metabolite GS-331007 13CD3,RO-2433 13CD3,PSI-6206 13CD3,GS-331007 13CD3	Others	Others
	PSI-6206 13CD3 is the deuterium labeled PSI-6206. PSI-6206 is a potent and selective HCV NS5B polymerase inhibitor.
T20160	GS-566500 psi-352707,psi352707,psi 352707
	GS-566500 is a compound of Sofosbuvir metabolite.
T12572	PSI-7409	Others	Others
	PSI-7409 is the active 5'-triphosphate metabolite of Sofosbuvir (PSI-7977).
T13852	PSI-7409 tetrasodium	Others	Others
	PSI-7409 tetrasodium is an active 5'-triphosphate metabolite of sofosbuvir (PSI-7977)(IC50s of 1.6, 2.8, 0.7 and 2.6 μM for GT 1b_Con1, GT 2a_JFH1, GT 3a, and GT 4a NS5B polymerases, respectively).

化合物

Cat.No: T6676

Synonym: 索非布韦,GS 7977,PSI-7977

Target: HCV Protease

Sofosbuvir impurity F

Cat.No: T12961

Synonym: 索非布韦杂质 F,Sofosbuvir 3',5'-Bis-(S)-phosphate

Target: HCV Protease

Sofosbuvir impurity G

Cat.No: T12962

Target: HCV Protease

Sofosbuvir 13CD3

Cat.No: T12954

Synonym: GS-7977 13CD3,PSI-7977 13CD3

Target: Others

Sofosbuvir impurity E

Cat.No: T12960

Target: Others

Sofosbuvir impurity K

Cat.No: T12966

Target: HCV Protease

Sofosbuvir impurity D

Cat.No: T12959

Target: Others

Sofosbuvir impurity H

Cat.No: T12963

Target: HCV Protease

Sofosbuvir impurity C

Cat.No: T12958

Target: Others

Sofosbuvir D6

Cat.No: T12955

Synonym: PSI-7977 D6,GS-7977 D6

Target: Others

Sofosbuvir impurity B

Cat.No: T12957

Target: Others

Sofosbuvir impurity N

Cat.No: T12969

Target: HCV Protease

Sofosbuvir impurity J

Cat.No: T12965

Target: HCV Protease

Sofosbuvir impurity I

Cat.No: T12964

Target: HCV Protease

Sofosbuvir impurity L

Cat.No: T12967

Target: HCV Protease

Sofosbuvir impurity A

Cat.No: T12956

Target: HCV Protease

Enantiomer of Sofosbuvir

Cat.No: T11195

Target: Others

Sofosbuvir impurity M

Cat.No: T12968

Target: HCV Protease

PSI-6206 13C,d3

Cat.No: T12571

Synonym: Sofosbuvir metabolite GS-331007 13CD3,RO-2433 13CD3,PSI-6206 13CD3,GS-331007 13CD3

Target: Others

Cat.No: T20160

Synonym: psi-352707,psi352707,psi 352707

Cat.No: T12572

Target: Others

PSI-7409 tetrasodium

Cat.No: T13852

Target: Others

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