E3 ligase Ligand-Linker Conjugates 12

(S,R,S)-AHPC-PEG3-N3 (VHL Ligand-Linker Conjugates 8) 包含基于 (S,R,S)-AHPC 的 VHL 配体和 3 个单元 PEG linker，是一种合成的 E3 连接酶配体-linker 偶联物。

cIAP1 Ligand-Linker Conjugates 12 is a chemical compound that combines an IAP ligand, which targets the E3 ubiquitin ligase, with a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 12, is valuable for creating SNIPERs[1].

(S,R,S)-AHPC-C6-PEG3-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker. (S,R,S)-AHPC-C6-PEG3-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1].

Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthesized conjugate compound known as an E3 ligase ligand-linker. It incorporates a cereblon ligand based on Thalidomide and a 3-unit PEG linker. This compound is specifically designed for use in PROTAC technology applications.

(S,R,S)-AHPC-PEG2-NH2 dihydrochloride (VH032-linker 12) 包含基于 (S,R,S)-AHPC 的 VHL 配体和 2 个单元 PEG linker，是一种合成的 E3 连接酶配体-linker 偶联物，可用于 PROTAC 分子的合成。