Decanoyl-L-carnitine (chloride)

Decanoyl-L-carnitine is an ester derivative of L-carnitine . It increases the formation of C24 fatty acid intermediates, as well as docosapentaenoic and docosahexaenoic acid in rat hepatocytes.

L-Carnitine (L(-)-Carnitine) 是一种人内源性分子，在人体内以蛋氨酸和赖氨酸为底物进行生物合成，并参与脂肪酸代谢。L-Carnitine 将长链脂肪酰辅酶A 转运到线粒体。L-Carnitine 能够改善许多先天性代谢错误的代谢失衡。

Acetyl-L-carnitine hydrochloride (Acetyl L-carnitine hydrochloride) 是一种由内源性左旋肉碱的乙酰化形式的盐酸盐组成的营养补充剂，具有潜在的神经保护、认知增强、抗抑郁和免疫调节活性。还可缓解化疗、糖尿病或其他疾病引起的周围神经病变。此外，乙酰左旋肉碱可能通过增加T淋巴细胞成熟来调节免疫反应，并可能下调促炎细胞因子对病毒(如SARS-CoV-2)的反应。它还可能破坏ACE2信号通路并抑制活性氧(ROS)的产生。

(±)-Carnitine chloride (Monocamin) 有D 和L 两种异构体。其中 L-carnitine 在脂肪酸的 β-氧化中起重要作用，也具有抗氧化作用和抗炎活性。

Acetyl-L-carnitine(RO 447190) 是一种可透过血脑屏障的氨基酸左旋肉碱，常作为膳食补充剂，对神经炎症有益。Acetyl-L-carnitine 具有神经保护作用，可用以研究像阿尔茨海默病类的神经疾病。

L-Carnitine-d3 Chloride 是 L-Carnitine Chloride 的氘代化合物。

Isobutyryl-L-carnitine chloride 是 DDI 评估的潜在临床 OCT1 生物标志物，可用于研究心力衰竭。

Decanoyl Chloride is used in the synthesis of an effective metalloproteinase inhibitor. Also acts as a reagent in the synthesis of reversible α-ketoheterocycle inhibitors of fatty acid amide hydrolase as potnetial analgesics.

L-Palmitoylcarnitine chloride (Palmitoyl-L-carnitine chloride)是一种脂肪酸代谢产物，具有抗血栓形成的作用，通过抵消tMCAO模型中的脑内血栓形成来保护小鼠免受缺血性中风。L-Palmitoylcarnitine chloride抑制心脏中的Na/K泵，抑制 FeCl 3诱导的动脉血栓形成，减轻了短暂性大脑中动脉闭塞（tMCAO）小鼠模型的脑内血栓形成和炎症。

Linoleoyl-L-carnitine is a naturally occurring long-chain acylcarnitine. Hepatic levels of linoleoyl-L-carnitine are increased following high-dose (200 mg kg) administration of isoniazid in mice.

L-Carnitine-d9 是 L-Carnitine 的氘代化合物。L-Carnitine 的 CAS 号为 541-15-1。L-carnitine 是一种人内源性分子，在人体内以蛋氨酸和赖氨酸为底物进行生物合成，并参与脂肪酸代谢。L-Carnitine 将长链脂肪酰辅酶A转运到线粒体。L-Carnitine 能够改善许多先天性代谢错误的代谢失衡。

Isovaleryl-L-carnitine-d9 HCl 是 Isovaleryl-L-carnitine HCl 的氘代化合物。

Isobutyryl-L-carnitine is a member of the class of compounds known as acylcarnitines. Isobutyryl-L-carnitine is a product of the acyl-CoA dehydrogenases.

Carnitine is a quaternary amine that occurs naturally in most mammalian tissue. Carnitine is present in relatively high concentrations in skeletal muscle and heart where it is involved in regulating energy metabolism. It has also been used to allow the en

Acetyl L-Carnitine-d3 Chloride 是 Acetyl L-Carnitine Chloride 的氘代化合物。

Palmitoyl-D-carnitine is a long-chain acylcarnitine, an isomer of palmitoyl-L-carnitine , and the D enantiomer of palmitoyl-DL-carnitine . It inhibits carnitine palmitoyltransferase with a Ki value of 2.1 mM for 14C-palmitoylcarnitine synthesis by erythrocyte membranes.

Oleoyl-L-carnitine是一种长链酰基肉碱，也是一种糖苷转运体2（GlyT2；IC50 = 340 nM）的抑制剂，对GlyT2比对GlyT1（IC50 = >10,000 nM）具有选择性。慢性肾脏病或接受初始血液透析的终末期肾脏病患者的血浆中Oleoyl-L-carnitine水平增高，这与心血管死亡率相关。

Hexanoyl-L-carnitine is a medium-chain acylcarnitine. It has been used in the synthesis of acylcarnitine benzyl esters.1 1.Gong, X.-w., Li, J.-p., Wu, J.-f., et al.Synthesis of carnitine benzyl esters as prodrugsJ. Chem. Res.2008(6)327-330(2008)

Stearoyl-L-carnitine chloride（Acylcarnitine C18:0） 是一种存在于小脑中的长链酰基肉碱，抑制 GlyT2 ，是研究脂代谢的重要组成部分。

Valeryl-L-carnitine is a short-chain acylcarnitine and a derivative of L-carnitine . Valeryl-L-carnitine levels increase in the serum of rhesus monkeys following exposure to 7 and 10 Gray units (Gy) of ionizing radiation.[1]

N-decanoyl-L-Homoserine lactone (C10-HSL) 是一种由克雷莫里色假单胞菌菌株 ND07产生的 N-acyl-homoserine lactone (AHL)。N-decanoyl-L-homoserine lactone 可抑制拟南芥的主根生长。N-decanoyl-L-homoserine lactone 处理可引起拟南芥根胞质游离 Ca2+ 和活性氧 (ROS) 浓度短暂和和立即升高，增加丝裂原激活蛋白激酶 6 (MPK6) 的活性，并促使一氧化氮 (NO) 的产生。

Lauroyl-L-carnitine (chloride) (Lauroyl-L-carnitine Hydrochloride)是一种酰基肉碱和表面活性剂，已被用于渗透猪肠细胞，以输送极性荧光探针荧光黄。

Myristoyl-L-carnitine chloride (L-Myristoylcarnitine chloride) 是人体的代谢物之一，与遗传代谢疾病有关。Tetradecanoylcarnitine 是研究糖尿病和自身免疫性肝炎的潜在标记物。

Palmitoyl L-Carnitine-d3 Hydrochloride 是 Palmitoyl L-Carnitine Hydrochloride 的氘代化合物。Palmitoyl L-Carnitine Hydrochloride 的 CAS 号为 18877-64-0。L-Palmitoylcarnitine chloride (Palmitoyl-L-carnitine chloride)是一种脂肪酸代谢产物，具有抗血栓形成的作用，通过抵消tMCAO模型中的脑内血栓形成来保护小鼠免受缺血性中风。L-Palmitoylcarnitine chloride抑制心脏中的Na K泵，抑制 FeCl 3诱导的动脉血栓形成，减轻了短暂性大脑中动脉闭塞（tMCAO）小鼠模型的脑内血栓形成和炎症。

Heptanoyl-L-carnitine is a medium-chain acylcarnitine and derivative of L-carnitine .

Carnitine facilitates the transport of fatty acids into the mitochondria to be used in fatty acid metabolism. It does so by accepting acyl groups from fatty acids complexed with coenzyme A, which yields esterified carnitine or acylcarnitines that enable the transport of fatty acyl groups into the inner mitochondrial matrix. β-Oxidation of fatty acids in mitochondria is inhibited by uncoupling conditions, thus changes in circulating levels of various acylcarnitines have been used to identify alterations in metabolic state.[1] [2] Arachidonoyl-L-carnitine formed from carnitine conjugated to arachidonic acid .

[(3R)-3-Hydroxydodecanoyl]-L-carnitine is an endogenous metabolite[1]. [1]. Hunter WG, et al. Metabolomic Profiling Identifies Novel Circulating Biomarkers of Mitochondrial Dysfunction Differentially Elevated in Heart Failure With Preserved Versus Reduced Ejection Fraction: Evidence for Shared Metabolic Impairments in Clinical Heart Failure. J Am Heart Assoc. 2016;5(8):e003190. Published 2016 Jul 29.

S-(5'-Adenosyl)-L-methionine chloride是一种天然产物，其产品编号为 TN6669，CAS号为 24346-00-7。S-(5'-Adenosyl)-L-methionine chloride可用作对照参考。

trans-2-Hexadecenoyl-L-carnitine is an endogenous metabolite in urine[1]. [1]. Pengxiang She, et al. Leucine and protein metabolism in obese Zucker rats. PLoS One. 2013;8(3):e59443.

trans-2-Octenoyl-L-carnitine is a synthetic carnitine.1It has been used as a standard for the detection of carnitines in human urine. 1.Yang, S., Minkler, P., and Hoppel, C.cis-3,4-methylene-heptanoylcarnitine: Characterization and verification of the C8:1 acylcarnitine in human urineJ. Chromatogr. B. Analyt. Technol. Biomed. Life Sci.857(2)251-258(2007)

Isovaleryl-L-carnitine is a naturally occurring acylcarnitine that is formed via metabolic conversion of L-leucine. It increases survival and decreases apoptosis in hepatocyte growth factor-deprived murine C2.8 hepatocytes when used at a concentration of 1 mM. Isovaleryl-L-carnitine inhibits amino acid deprivation-induced proteolysis and autophagy in isolated perfused rat liver when used at concentrations of 77 and 100 μM, respectively. Increased levels of isovaleryl carnitine are associated with isovaleryl-CoA dehydrogenase deficiency (isovaleric acidemia).

Butyryl-L-carnitine is a butyrate ester of carnitine. It is an inhibitor of intestinal transporters, blocking carnitine uptake by the carnitine transporter and glycine transport by the amino acid transporter in human retinal pigment epithelial (HRPE) cells (IC50s = 1.5 μM and 4.6 mM, respectively).

L-Carnitine tartrate is a Carnitine/ Constituent of striated muscle and liver. It is used to treatment of hyperlipoproteinemias.

Decanoyl carnitine-d3 HCl 是 Decanoyl carnitine HCl 的氘代化合物。