|
L7850
|
高溶解性3D结构多样性片段化合物库
|
|
1081 compounds
|
|
高溶解性3D结构多样性片段库包含1081个化合物。
|
|
DC1140
|
特权片段注释化合物库-Ligand-gated
|
|
9028 compounds
|
|
|
|
DC1180
|
特权片段注释化合物库-Lyases
|
|
19530 compounds
|
|
|
|
DC1150
|
特权片段注释化合物库-GPCR Family B
|
|
9320 compounds
|
|
|
|
DC1170
|
特权片段注释化合物库-Oxidoreductases
|
|
8812 compounds
|
|
|
|
DC1190
|
特权片段注释化合物库-Sigma Opioid receptors
|
|
8724 compounds
|
|
|
|
DC1040
|
特权片段注释化合物库-Transferases
|
|
23001 compounds
|
|
|
|
DC1030
|
特权片段注释化合物库-Epigenetics
|
|
9196 compounds
|
|
|
|
DC1100
|
特权片段注释化合物库-GPCR Frizzled family
|
|
3434 compounds
|
|
|
|
DC1200
|
特权片段注释化合物库-Isomerases
|
|
1206 compounds
|
|
|
|
DC1050
|
特权片段注释化合物库-Voltage-gated
|
|
17952 compounds
|
|
|
|
DC1110
|
特权片段注释化合物库-Proteases
|
|
22863 compounds
|
|
|
|
DC1010
|
特权片段注释化合物库-GPCR Family A
|
|
24763 compounds
|
|
|
|
DC1000
|
特权片段注释化合物库
|
|
190000 compounds
|
|
The database contains 190k small molecules divided into 23 sub libraries each focused at a specific target.
According to the recent studies, molecules acting on a particular target or class of targets usually have characteristic moieties (PF) containing key binding points responsible for activity, e.g. hinge-binding fragments. We used this principle for the statistical analysis of the reported active molecules and corresponding targets for the annotation of pre-filtered ChemDiv in house colle...
|
|
DC1130
|
特权片段注释化合物库-Phosphodiesterases
|
|
13154 compounds
|
|
|
|
DC1060
|
特权片段注释化合物库-Kinases
|
|
18350 compounds
|
|
|
|
DC1220
|
特权片段注释化合物库-Aminoacyltransferases
|
|
3008 compounds
|
|
|
|
DC1210
|
特权片段注释化合物库-Phosphatases
|
|
15354 compounds
|
|
|
|
DC1160
|
特权片段注释化合物库-Toll-like and Il-1 receptors
|
|
3536 compounds
|
|
|
|
DC1090
|
特权片段注释化合物库-Ligases
|
|
11828 compounds
|
|
|
|
DQ3000
|
Factor XIa化合物库
|
|
6500 compounds
|
|
|
|
DC1080
|
特权片段注释化合物库-GPCR Taste family
|
|
2675 compounds
|
|
|
|
DC1120
|
特权片段注释化合物库-Thrombopoietin receptors
|
|
4908 compounds
|
|
|
|
DC1230
|
特权片段注释化合物库-Beta amyloid A4 protein
|
|
4617 compounds
|
|
|
|
DC1070
|
特权片段注释化合物库-GPCR Family C
|
|
5071 compounds
|
|
|
|
DC1020
|
特权片段注释化合物库-Spiro Library
|
|
20563 compounds
|
|
|
|
L1380
|
转录因子库
|
|
704 compounds
|
|
704种转录因子靶向、结构新颖的化合物；
|
|
L2610
|
神经递质受体化合物库
|
|
1513 compounds
|
|
1513种与神经递质受体相关的化合物，用于高通量、高内涵筛选；
|
|
L6900
|
稀有天然产物库
|
|
284 compounds
|
|
284种稀有天然产物的集合，可以用于高通量和高内涵筛选；
|
|
L9200
|
药物功能重定位化合物库
|
|
4240 compounds
|
|
4240种全球上市药物和临床药物的独特集合，可用于高通量筛选和高内涵筛选，是老药新用、新的药物靶点筛选和细胞诱导的有效工具。
|
|
L1000
|
上市药物库
|
|
2863 compounds
|
|
2863个上市药物化合物集合，可用于高通量筛选和高内涵筛选；
|
|
L6020
|
天然产物单体化合物库
|
|
19377 compounds
|
|
19377 种精选天然产物集合，结构多样，遍布多种动植物与微生物；
|
|
L2300
|
离子通道库
|
|
946 compounds
|
|
946种与离子通道相关的生物活性小分子化合物的特有集合，用于离子通道相关的疾病和药物研究，可用于高通量筛选和高内涵筛选；
|
|
L6130
|
萜类天然产物库
|
|
349 compounds
|
|
349种萜类天然产物的独特集合，可用于高通量筛选和高内涵筛选；
|
|
DP9200
|
DGK抑制剂库
|
|
12000 compounds
|
|
包含12000种类药化合物，源自知名品牌Chemdiv，从160万小分子中百里挑一；
|
|
L6700
|
抗癌天然产物库
|
|
1471 compounds
|
|
1471种已知活性天然产物的独特集合，是肿瘤药物开发、抗癌先导化合物筛选等领域的有力工具，可用于HTS和HCS。
|
|
L7700
|
神经再生化合物库
|
|
529 compounds
|
|
529种神经再生相关化合物的独特集合，可用于高通量筛选和高内涵筛选；
|
|
NY1000
|
天然产物衍生物库
|
|
4000 compounds
|
|
22个天然产物骨架，4000个天然产物衍生物；
|
|
VM1400
|
多样性核心库Part2
|
|
25920 compounds
|
|
分子量<500，主要集中于250-450之间，方便后续的改造优化；
|
|
DF4500
|
多样性核心库Part1
|
|
50000 compounds
|
|
绝大部分分子量<500，主要集中于250-450之间，方便后续的改造优化；
|
|
L9500
|
表型筛选靶点鉴定库
|
|
1832 compounds
|
|
1832种靶点明确的已知活性化合物，适合表型筛选；
|
|
L9600
|
多肽分子库
|
|
533 compounds
|
|
533种多肽类分子，可用于多肽药物开发及信号转导通路和作用机制研究；
|
|
L6120
|
黄酮类天然产物库
|
|
477 compounds
|
|
477种黄酮类天然产物的独特集合，可用于高通量筛选和高内涵筛选；
|
|
L6210
|
藏药化合物库
|
|
754 compounds
|
|
754种藏药来源的天然产物分子集合，可以用于高通量和高内涵筛选；
|
|
L1710
|
抗COVID-19化合物库
|
|
1160 compounds
|
|
1160种对SARS-CoV-2有抑制作用或潜在抑制作用的化合物集合，可用于高通量和高内涵筛选；
|
|
L6030
|
天然产物衍生物虚筛化合物库
|
|
135000 compounds
|
|
13.5万种天然产物衍生物，并且在持续增加中；
|
|
CL0137
|
E1/E2/E3 Enzyme inhibitor kit
|
|
|
|
|
|
CL0067
|
Sodium Channel inhibitor kit
|
|
|
|
|
|
CL0066
|
P450 inhibitor kit
|
|
|
|
|
|
CL0103
|
mGluR agonist/antagonist/modulator kit
|
|
|
|
|
|
CL0141
|
Notch pathway inhibitor kit
|
|
|
|
|
|
CL0126
|
Androgen Receptor antagonist kit
|
|
|
|
|
|
CL0139
|
ROS inhibitor kit
|
|
|
|
|
|
CL0132
|
DHFR inhibitor kit
|
|
|
|
|
|
L1010
|
FDA上市及药典收录分子库
|
|
3158 compounds
|
|
3158个上市及药典分子集合，可用于高通量筛选和高内涵筛选；
|
|
CL0092
|
GSK-3 inhibitor kit
|
|
|
|
|
沪公网安备 31010602006700号
