Cintirorgon sodium

Cintirorgon (LYC-55716) is an orally active RORgamma agonist with potential immunomodulatory and antineoplastic activities. LYC-55716 selectively binds to the RORg, and binds to ROR response elements, enhancing the function, proliferation, and survival of

Cintirorgon (LYC-55716) 是一种首创的、口服有活力的的RORγ选择性激动剂。它通过调节 RORγ 表达的 T 淋巴免疫细胞的基因表达，提高效应子功能，降低免疫抑制，抑制肿瘤生长，提高生存率。