[Pro3]-GIP

GIP receptor antagonist (IC50 = 2.6μM). Inhibits GIP-stimulated insulin release from pancreatic β cells in vitro. In ob/ob mice, blocks the effects of GIP on insulin release and plasma glucose levels. Also improves intraperitoneal glucose tolerance, insul

High affinity rat GIP receptor partial agonist (Kd = 13 nM). Increases cAMP accumulation in COS-7 cells transfected with rat GIP receptor, while also acting as a competitive antagonist of GIP.

[Pro3]-GIP (Mouse) acetate 是鼠源[Pro3]-GIP。[Pro3]-GIP 是一种 GIP receptor 拮抗剂。

(Pro3) GIP, human ((Pro3)Gastric Inhibitory Peptide, human) 是一种有效、稳定和特异性的人 GIP 受体完全激动剂。(Pro3) GIP, human 对人 GIPR 具有高结合亲和力，Ki Kd 值为 0.90 nM。(Pro3) GIP, human 可用于肥胖相关糖尿病的研究。