isotopes

L-Lysine-13C6-15N2 Hydrochloride 是一种 13C 和 15N 标记的 L-Lysine hydrochloride。L-lysine hydrochloride 是人类必需的氨基酸，也是一种常见的食品添加剂，需要通过饮食摄入。L-lysine hydrochloride 可刺激胃蛋白酶与胃酸的分泌，提高胃液分泌功效，促进幼儿生长与发育。

SADDNIKTPAE(Arg-13C6,15N4)LLGPLPPSADDNLKT (TFA) 为SADDNIKTPAE-LLGPLPPSADDNLKT (TFA) 同位素标记版本,其中包含13C 和15N,并以三氟乙酸盐形式存在.

Erlotinib-13C6 (CP-358774-13C6) is a 13C-labeled Erlotinib. Erlotinib is a directly acting EGFR tyrosine kinase inhibitor, with an IC50 of 2 nM for human EGFR[1]. Erlotinib reduces EGFR autophosphorylation in intact tumor cells with an IC50 of 20 nM. Erlotinib is used for the treatment of non-small cell lung cancer[1].Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process[2]. [1]. Moyer JD, et al. Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase. Cancer Res. 1997, 57(21), 4838-4848.[2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

2-Bromonaphthalene-d7 是 2-Bromonaphthalene 的氘代标记形式.这种稳定同位素标记化合物能够用于代谢分析,实现对单个原子的运动进行精准追踪和量化.

4-Acetyl-N-methylaniline-13C,d3 (1-(4-(Methylamino)phenyl)ethanone-13C,d3)为4-Acetyl-N-methylaniline的13C和氚(D)标记同位素版本。这种化合物带有稳定或放射性同位素标记，常用于代谢分析中，以准确跟踪和量化单个原子的移动。

Angiotensin I-13C6,15N (human, mouse, rat) TFA 是经过13C 和15N 标记的蛋白质,具体为Angiotensin I (human, mouse, rat) TFA 的同位素标记形式。此化合物作为angiotensin II的前体，在血管紧张素转化酶 (ACE) 的作用下被裂解, 产生angiotensin II。