yeasts

Sorbic acid 是一种高效安全无毒的食品防腐剂。它可抑制大多数霉菌，酵母和某些细菌。

Isavuconazole (RO-0094815) 是一种三唑类前药，对酵母、霉菌和二型真菌具有抗真菌活性。它抑制麦角固醇生物合成，导致真菌膜结构和功能的破坏。它是 CYP3A4抑制剂。

Piperazinomycin is an antifungal antibiotic, showing inhibitory activity against fungi and yeasts, especially against Trichophyton.

Naftifine hydrochloride (Naftifine HCl) 是一种抗生素。它具有抗真菌活性，对皮肤真菌、曲霉、Sporothrix schenckii、假丝酵母属的酵母有抑制作用。

Butoconazole nitrate (RS 35887) 是一种咪唑类抗真菌药物，可治疗由白色念珠菌引起的阴道感染。它可通过抑制类固醇合成起到抗菌作用。

Methylchloroisothiazolinone Methylisothiazolinone Mixture(Kathon 886MW)是一种异噻唑啉酮类防腐剂，广泛用于化妆品，能够抑制细菌、酵母和真菌的生长，同时可能引起接触性皮肤过敏。Methylisothiazolinone 可以激活人支气管上皮细胞中的基质金属蛋白酶 (MMPs) 来诱导细胞凋亡和炎症反应。

Nikkomycin Z (Nikkomycin Z from Streptomyces tendae) 是一种选择性竞争性几丁质合成抑制剂。它是一种核苷肽，可作为几丁质合酶底物 UDP-N-乙酰氨基葡萄糖的竞争性类似物，具有抗真菌作用。

Idarubicin 是一种有效的、具有口服活性的蒽环类抗白血病剂。Idarubicin 抑制拓扑异构酶 II，干扰 DNA 复制和 RNA 转录。Idarubicin 可诱导 DNA 损伤。Idarubicin 抑制 DNA 合成和 c-myc 表达。Idarubicin 还抑制细菌和酵母菌的生长。

Brolaconazole为一种咪唑衍生物，对致病真菌、霉菌、酵母及革兰氏阳性细菌具有强效的抗微生物活性。

Isavuconazole D4 is a deuterium labeled Isavuconazole. Isavuconazole is a triazole prodrug with antifungal activity against yeasts, molds, and dimorphic fungi.

Chloroazodin 是一种具有强大抗菌作用的脂肪族氯胺衍生物，对多种微生物、真菌、酵母和疟原虫都有效，且毒性低。

Ajoene is a disulfide that has been found inA. sativumand has diverse biological activities, including antibacterial, anticancer, antiplatelet, and antioxidant properties.1,2,3,4It is active against Gram-positive (MICs = 5-160 µg ml) and Gram-negative bacteria (MICs = 136-200 µg ml), as well as yeasts (MICs = 10-20 µg ml).1Ajoene is cytotoxic to mouse melanoma cells (IC50= 18 µM), as well as human colon, lung, mammary, and pancreatic cancer cells (IC50s = 7-41 µM).2It reduces tumor growth in a B16 BL6 mouse model of melanoma when administered at a dose of 25 mg kg every other day and decreases the number of lung metastases when administered prior to tumor cell inoculation at doses ranging from 1-25 mg kg. It inhibits ADP- or collagen-induced platelet aggregation in isolated baboon platelets when used at concentrations ranging from 75 to 150 µg ml and in platelet-rich plasma isolated from baboons when administered at a dose of 25 mg kg.3Ajoene (25 mg kg) prevents thrombus formation on damaged arterial walls in heparinized pigs in anin situmodel of thrombogenesis.5It also reduces high-fat diet-induced hepatic steatosis, histopathological markers of liver damage, thiobarbituric acid reactive substances (TBARS) formation, and protein oxidation in a mouse model of non-alcoholic fatty liver disease (NAFLD).4 1.Naganawa, R., Iwata, N., Ishikawa, K., et al.Inhibition of microbial growth by ajoene, a sulfur-containing compound derived from garlicAppl. Environ. Microbiol.62(11)4238-4242(1996) 2.Taylor, P., Noriega, R., Farah, C., et al.Ajoene inhibits both primary tumor growth and metastasis of B16 BL6 melanoma cells in C57BL 6 miceCancer Lett.239(2)298-304(2006) 3.Teranishi, K., Apitz-Castro, R., Robson, S.C., et al.Inhibition of baboon platelet aggregation in vitro and in vivo by the garlic derivative, ajoeneXenotransplantation10(4)374-379(2003) 4.Han, C.Y., Ki, S.H., Kim, Y.W., et al.Ajoene, a stable garlic by-product, inhibits high fat diet-induced hepatic steatosis and oxidative injury through LKB1-dependent AMPK activationAntioxid. Redox Signal.14(2)187-202(2011) 5.Apitz-Castro, R., Badimon, J.J., and Badimon, L.A garlic derivative, ajoene, inhibits platelet deposition on severely damaged vessel wall in an in vivo porcine experimental modelThromb. Res.75(3)243-249(1994)

Termicin，一种Pseudacanthotermes spiniger源抗菌肽，对革兰氏阳性菌、丝状真菌及酵母具有活性。

Kalafungin antimicrobial agent that is inhibitory in vitro against a variety of pathogenic fungi, yeasts, protozoa, gram-positive bacteria, and, to a lesser extent, gram-negative bacteria.

Lydicamycin是从一种被鉴定为溶性链霉菌的放线菌菌株的发酵液中分离出的新型抗生素，Lydicamycin对革兰氏阳性菌和某种酵母菌有活性，但对革兰氏阴性菌无活性。[2]

3-beta-O-(trans-p-Coumaroyl)maslinic acid is a DNA polymerase B inhibitor. It shows antimicrobial activity on Gram-positive bacteria and yeasts.

Rose Bengal Chloramphenicol Agar 是一种用于从多种食品中枚举酵母和霉菌的选择性培养基。培养基具备中性 pH 值，氯霉素（Chloramphenicol）作为选择性试剂以抑制细菌的生长。

Quinolactactin A is a quinolone fungal metabolite originally isolated from Penicillium. It inhibits TNF production induced by LPS in murine peritoneal macrophages (IC50 = 12.2 μg/ml). It is not active against a variety of bacteria, fungi, and yeasts. Quinolactacin A is a mixture of quinolactacin A1 and A2.

Naftoxate is an antimicotic. It is effective against both gram-positive and gram-negative bacteria as well as yeasts and other fungi in plant cell culture.

Stigmatellin 是一种从粘细菌细胞质中提取的抗生素，具备针对酵母菌、丝状真菌和部分革兰氏阳性菌的抗菌活性。此外，Stigmatellin 是一种有效的光合作用电子传输抑制剂。其作用机制涉及抑制以各类糖类、多糖及柠檬酸循环中的酸为底物的RNA和蛋白质合成。Stigmatellin 在光系统II的还原侧和细胞色素b6 f复合体中具有两个抑制位点。该化合物在抗微生物及光合作用研究领域显示出潜在的应用价值。

Enfumafungin，一种从Hormonema carpetanum菌提取的三萜糖苷，具有抗真菌特性，主要通过作为(1,3)-beta-D-葡聚糖合酶抑制剂影响真菌细胞壁发挥作用。其对酵母和多数真菌（除隐球菌外）有效，但不会抑制枯草芽孢杆菌的生长。

Parconazole Free Base is used in veterinary as an oral fungicide with a broad-spectrum activity against dermatophytes, yeasts, and others fungi. This compound does not have any antibacterial effect. The mechanism of action involves inhibition of the fungal cytochrome P450 dependent 14alpha-dimethylation of lanosterol to ergosterol.

Potato dextrose agar 是一种常用于培养酵母菌、霉菌和蘑菇等真菌的培养基。

3-beta-O-(trans-p-Coumaroyl)maslinic acid shows antimicrobial activity on Gram-positive bacteria and yeasts.