y-11

focal adhesion kinase (FAK) inhibitor

1b-Hydroxy-11a,13-dihydroalantolactone 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T125418，CAS号为 200703-30-6。

(3β,7β,12β,20Z)-3,7,12-Trihydroxy-11,15,23-trioxo-lanost-8,20-dien-26-oic acid, a lanostane triterpenoid, demonstrates significant inhibitory effects on nitric oxide (NO) production in BV-2 microglia cells induced by n LPS, with an IC50 value of 9.55 uM. Moreover, this compound possesses anti-inflammatory properties.

WAY-118959-A（GM-90257）是一种αTAT1（α-tubulin acetyltransferase 1）的竞争性抑制剂，直接与α-微管蛋白结合并抑制微管乙酰化，减弱肿瘤在体内的生长并引起MDA-MB-231的凋亡。

9-Chloromethyl-10-Hydroxy-11-F-Camptothecin是一款喜树碱类衍生化合物，具有DNA拓扑异构酶I (Topo I)抑制活性，应用于癌症治疗的研究领域。

WAY-119918为一种用于生化反应研究的活性分子。

10,13-epoxy-11-methyl-Octadecadienoic Acid 是一种活性分子，可用于生命科学相关研究，其 CAS 号为 57818-39-0。

18-Hydroxy-11-deoxy Corticosterone (18-OH-DOC) is a mineralocorticoid produced by the zona fasciculata of the adrenal gland, with its biosynthesis regulated by adrenocorticotropic hormone (ACTH) and angiotensin II. This regulation heightens 18-OH-DOC production in isolated human adrenal glomerulosa cells and allows for its formation from 11-deoxy corticosterone (DOC) in human SK-MEL188 melanoma cells. As an intermediate in progesterone metabolism, 18-OH-DOC can be converted to aldosterone in rat adrenal glands' capsular portion. Its continuous infusion (200 μg rat per day) has been shown to raise systolic blood pressure in uninephrectomized saline-drinking rats, and elevated plasma levels of 18-OH-DOC have been observed in the adb db mouse model of type 2 diabetes.

11-Deoxy-11-methylene PGD2 (11d-11m-PGD2) 为 Prostaglandin D2 类似物，其结构中的 11-酮基由环外亚甲基替代。该化合物有效激活在 Indomethacin 存在下受到抑制的脂肪存储。

23S-hydroxy-11,15-dioxo-ganoderic acid DM is a natural product

3beta,7beta,15beta-trihydroxy-11-oxo-lanosta-8-en-24->20 lactone is a natural product

14-Deoxy-11-oxoandrographolide is a natural product from Andrographis paniculata

14-Deoxy-11,12-didehydroandrographiside是一种天然产物，属于爵床科穿心莲属，其产品编号为 TN2622，CAS号为 141973-41-3。14-Deoxy-11,12-didehydroandrographiside可用作对照参考。

3β-Acetoxy-urs-11-en-28,13-olide exhibits significant protein tyrosine phosphatase 1B (PTP1B) inhibitory activity, it is a mixed-type PTP1B inhibitor. It exhibits weak-moderate antiproliferative activity against the A2780 human ovarian cancer cell line.

3β-Hydroxy-urs-11-en-28,13β-olide shows a potent concentration-independent cytoprotective effect against CCl4-induced injury on human hepatoma cell line relative to silymarin as a reference standard. It exhibits weak-moderate antiproliferative activity ag

4-Hydroxy-11,12,13-trinor-5-eudesmen-7-one 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3032，CAS号为 133369-42-3。

14-Deoxy-11-hydroxyandrographolide shows potent cell differentiation-inducing activity towards mouse myeloid leukemia (M1) cells.

ent-15α-Acetoxy-11α-hydroxykaur-16-en-19-oic acid 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5621，CAS号为 70324-38-8。

3β-Acetoxy-11α,12α-epoxyoleanan-28,13β-olide是一种天然产物，其产品编号为 TN5958，CAS号为 35738-25-1。3β-Acetoxy-11α,12α-epoxyoleanan-28,13β-olide可用作对照参考。

3-Deoxy-11,13-dihydroisosecotanapartholide 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6365，CAS号为 572924-43-7。

1β,4β-Dihydroxy-11,12,13-trinoreudesm-5-en-7-one 属于倍半萜类化学物质。

3β,7β-Dihydroxy-11,15,23-trioxo-lanost-8,16-dien-26-oic 是在 Ganoderma lucidum 中发现的三萜类化合物。

14-Deoxy-11,12-didehydroandrographolide (AP10) 是一种 Andrographolide 的类似物，能够抑制 NF-κB 活性。

BAY 11-7082 (BAY 11-7821) 是一种 NF-κB 抑制剂，可抑制 TNFα 诱导的 IκBα 磷酸化 (IC50=10 μM)。BAY 11-7082 也是一种泛素特异性蛋白酶 USP7 和 USP21 的抑制剂 (IC50=0.19 0.96 μM)。