uterine smooth muscle

14-Deoxyandrographolide 是穿心莲中的一种天然产物，是一种钙通道阻断剂，具有保肝功效。它通过诱导 TNFRSF1A 的释放，使肝细胞对 TNF-α 介导的凋亡脱敏。

Isoxsuprine hydrochloride (Isolait) 是 β 肾上腺素受体激动剂和NMDA 受体拮抗剂，对子宫肌层和胎盘的 β 肾上腺素受体的Ki 值分别为 13.65 和 3.48 μM。

Ritodrine hydrochloride (NSC 291565) 是一种 β-2肾上腺素受体激动剂。

Sigetin affects the transport of calcium and magnesium in uterine smooth muscle and can be used in fetal development.

Neuromedin C is a bombesin-like neuropeptide that stimulates uterine smooth muscle contraction and the release of gastrin , somatostatin, and amylase in rats. Neuromedin C is a truncated form of gastrin-releasing peptide corresponding to the GRP amino acids 18-27. It inhibits GRP and bombesin binding to rat pancreatic membranes (IC50s = 0.4 and 2.2 nM, respectively), which can be reduced by sodium chloride and guanylyl imidodiphosphate . Neuromedin C induces scratching and mast cell degranulation in mice when administered intradermally at doses ranging from 1 to 300 nmol site, which is inhibited by the BB2 bombesin receptor agonist RC-3095 and reduced in mast cell-deficient mice. Neuromedin C (3.2 nmol kg, i.p.) reduces rat glucose consumption by approximately 50% for up to one hour.

15(S)-15-methyl PGE2 is a potent, metabolically stable analog of PGE2. It is a potent gastric antisecretory and antiulcer compound. 15(S)-15-methyl PGE2 binds to human myometrium with twice the affinity of PGE2 and is ten times more potent than PGE1 in contracting uterine smooth muscle.

C16 globotriaosylceramide is an endogenous sphingolipid found in mammalian cell membranes that is synthesized from C16 lactosylceramide . C16 globotriaosylceramide acts as a receptor for Shiga toxin in B cell-derived Raji cells and THP-1 monocytes. It accumulates in endothelial cells, pericytes, vascular smooth muscle cells, renal epithelial cells, dorsal ganglia neuronal cells, and myocardial cells in patients with Fabry disease. C16 globotriaosylceramide is also upregulated in plasma of patients with ovarian carcinoma compared to those with benign ovarian tumors or uterine fibroids.

Oxytocin (Oxytocin (Syntocinon)) 是哺乳动物的神经垂体激素，是多效的下丘脑肽，是催产素受体的配体，有助于分娩、哺乳和亲社会行为。Oxytocin 有刺激乳腺分泌乳汁，在分娩过程中促进子宫平滑肌的收缩，促进母爱的作用。

Isoxsuprine Free Base is a beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle. Its vasodilating actions are greater on the arteries supplying skeletal muscle than on those supplying skin. It is used in the treatment of peripheral vascular disease and in premature labor.

PDC31 (THG113.31; ILGHXDYK) 是FPProstaglandin Receptor 的变构和非竞争性抑制剂。PDC31是基于D-氨基酸的寡肽，用作平滑肌收缩剂。PDC31 在体内降低子宫收缩的强度和持续时间，可用于早产和原发性痛经 (PD) 的研究。PDC31 还增强人子宫肌层细胞中 Ca2+依赖性大电导 K+通道。

13-Hydroxylupanine是甜羽扇豆中一种典型的生物碱。它具有阻断神经节传递、降低心肌收缩力以及收缩子宫平滑肌的作用。

3-Epioleanolic acid 是一种分离自马鞭草的有效成分，具有抗炎作用。