urchin

3-hydroxycoumarin 是一种 15-LOX-1的有效氧化还原抑制剂，近期被证明能保护海胆生殖细胞免受紫外线 B 的损伤。

Speract TFA(76901-59-2(free base)) 是一种海胆卵肽，可调节精子活力，也可刺激精子线粒体代谢。

Resact is an extracellular peptide from egg jelly of the sea urchin Arbacia punctulata.

11(R)-HEPE is produced by the oxidation of EPA by 11(R)-LO. This enzymatic activity and the resulting 11(R)-hydroxy acid have been isolated from the sea urchin S. purpuratus.

11(R)-HETE is biosynthesized by 11(R)-LOs of the sea urchin, S. purpuratus, and the fresh water hydra, H. vulgaris. The biological activity of 11(R)-HETE relates to oocyte maturation and tentacle regeneration, respectively, in these two species. 11(R)-HETE is also produced when aspirin-treated recombinant COX-2 is incubated with arachidonic acid. Stereochemical assignment of the (R) enantiomer is based on comparison of chiral HPLC retention times to published results.

Cyclic ADP-ribose (cADP-ribose) is a calcium mobilizing nucleotide that is biosynthesized from NAD+ by cADP-ribose synthases, including CD38. cADP-Ribose appears to activate calcium channels in intracellular membranes, which in turn activate ryanodine receptors. 8-bromo-cADP-Ribose is a stable, cell-permeable analog that blocks calcium release evoked by cADP-ribose in sea urchin egg homogenates with an IC50 value of 1.7 μM. It is commonly used to investigate intracellular signaling through cADP-ribose in isolated cells and tissues.

Speract 是调节精子活力的海胆蛋肽，也能够刺激精子线粒体代谢。

12(R)-HEPE, a monohydroxy fatty acid derived from EPA in the eggs of the sea urchin S. purpuratus, has a biological activity that, while not extensively documented, may resemble that of 12(R)-HETE (Catalog No.34560).

Aphidicolin 17-acetate 是一种专一性抑制真核 DNA 聚合酶 α (DNA polymerase α) 的化合物。它对 DNA 聚合酶 β 和 γ 无影响。Aphidicolin 17-acetate 显著抑制海胆胚胎和 HeLa 细胞体内的 DNA 合成，但不影响 RNA 和蛋白质合成。