tr 3

Tr-PEG3-OH is a non-cleavable, three-unit PEG ADC linker employed for ADC synthesis, specifically in the context of antibody-drug conjugates (ADCs).

TRβ agonist 3 (Compound 3) 是TRβ的有效激动剂，它是一种新的潜在 TRβ 选择性拟甲状腺素。在体外研究中，TRβ agonist 3 可减少 HepG2 中的脂质积累并促进脂肪分解。

cytoplasmic peptide of the neurotrophin receptor p75NTR

NTR 368 TFA, 衍生自p75神经营养蛋白受体(p75NTR)，对应人类受体残基368-381，胶束脂质存在促使其倾向形成螺旋结构。该肽为神经细胞凋亡(apoptosis)的有效诱导剂。

Protein conjugates in tissue regeneration 3 (PCTR3) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid . DHA is oxidized to 16S,17S-epoxy-protectin, which is converted to PCTR1 by glutathione S-transferase and to PCTR2 and PCTR3 via peptidases. PCTR3 is found in infected mouse spleens and resolving exudate as well as isolated human spleen and septic plasma. It is also found in both M1 and M2 macrophages differentiated from isolated human monocytes.

5’-O-DMTr-3’-O-phthalimidopropyl cytidine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 TNU1661。

N1-Ethyl-2’-O-TBDMS-5’-O-DMTr-3’-phosphoramidite 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 TNU1141。

N6-Bz-5'-O-DMTr-3'-O-methyladenosine-2'-O-CED-phosphoramidite is a Nucleoside Phosphoramidite.

5’-DMTr-3’dA(Bz)-methylphosphonamidite 是嘌呤核苷类似物，具备广泛抗肿瘤活性，主要用于靶向惰性淋巴系统恶性肿瘤。其作用机制主要通过抑制DNA合成，诱导细胞凋亡（apoptosis）实现。

BN-81,674 is a bioactive chemical.

Maresin conjugates in tissue regeneration 3 (MCTR3) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid in macrophages. DHA is oxidized to maresin 1 , which is converted to MCTR1 by glutathione S-transferase Mu 4 or leukotriene C4 synthase, then to MCTR2 by γ-glutamyl transferase, and to MCTR3 by dipeptidase. MCTR3 accelerates tissue regeneration in planaria (1 and 100 nM) approximately as potently as MCTR2 and more potently than MCTR1. Pretreatment with MCTR3 prior to E. coli administration in mice reduces neutrophil infiltration, shortens the inflammatory resolution period, and increases phagocytosis of E. coli by macrophages. When administered at a dose of 100 ng 12h post E. coli infection in a mouse model of peritonitis, MCTR3 selectively reduces the amount of the eicosanoids PGD2 , PGE2 , PGF2α , and TXB2 in the exudate.

Nucleoside Derivatives –3'-Deoxy nucleosides;Nucleoside Phosphoramidites

Veldoreotide (DG3173) TFA，一种生长抑素类似物，能够结合并激活SSTR 2 4 5。其在腺瘤中抑制生长激素分泌的效果相较于Octreotide更为显著。此外，Veldoreotide亦展现出作为镇痛剂的潜力。

Cortistatin-29 is a neuropeptide that is structurally similar to somatostatin-28. It is produced by cleavage of preprocortistatin to procortistatin, which is cleaved at dibasic amino acids to form cortistatin-29 and cortistatin-14 as well as other partial cleavage products. Cortistatin mRNA is expressed in the human brain and in interneurons of the rat hippocampus and cerebral cortex. Cortistatin-29 binds to somatostatin (SST) receptors with IC50 values of 2.8, 7.1, 0.2, 3, and 13.7 nM for SST1-5, respectively. Cortistatin-29 is found at similar levels as cortistatin-14 in mouse AtT20 cells but is secreted at a lower level. Cortistatin-29 corresponds to residues 85-112 of the rat peptide sequence.

N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite 是一种腺嘌呤核苷类似物，具有潜在的血管扩张活性和抗癌活性，可用于研究癌症。

N4-Bz-5'-O-DMTr-3'-deoxy-3'-fluoro-beta-D-xylofuranosyl cytidine-2'-CED-phosphoramidite 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 TNU1666，CAS号为 1555759-30-2。

Veldoreotide, also known as Somatoprim, is a unique somatostatin receptor subtypes 2-, 4- and 5-selective analogue which effectively reduces GH secretion in human GH-secreting pituitary adenomas, even in Octreotide non-responsive tumours.

5'-DMTr-3'dA(Bz)-methyl phosphonamidite is a Nucleoside Phosphoramidite.

Nucleoside Derivatives –3'-Deoxy nucleosides; protected nucleosides w NH2 OH open