thalidomide-piperazine

Thalidomide-Piperazine 5-fluoride is a compound developed by synthesizing an E3 ligase ligand-linker conjugate. It incorporates a cereblon ligand derived from Thalidomide and utilizes a linker commonly employed in PROTAC technology.

Thalidomide-piperazine hydrochloride is a chemical compound with potential applications in the research of leprosy and multiple myeloma. It serves as a valuable tool in developmental biology, facilitating significant discoveries in the biochemical pathways of limb development [1].

Thalidomide-Piperazine 5-fluoride hydrochloride，作为Thalidomide衍生物，是一种cereblon(CRBN)抑制剂，用作E3 泛素连接酶的配体(Ligands for E3 Ligase)，适用于PROTACs合成。

Thalidomide-piperazine-Boc is an intermediate utilized for synthesizing BCL6 PROTAC, which targets B-cell lymphoma 6 protein.

Thalidomide-Piperazine-Piperidine is a compound composed of a synthesized E3 ligase ligand-linker conjugate. It combines a cereblon ligand derived from Thalidomide with a linker commonly used in PROTAC technology.

Thalidomide-Piperazine-PEG2-NH2 is a synthetic E3 ligase ligand-linker conjugate that combines the cereblon ligand derived from Thalidomide with a linker commonly utilized in PROTAC technology.

Thalidomide-Piperazine-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that combines the Thalidomide-based cereblon ligand with a linker commonly used in PROTAC technology, serving as an E3 ligase recruiter.

Thalidomide-Piperazine-Piperidine hydrochloride is a synthesized compound that serves as an E3 ligase ligand-linker conjugate. It combines the cereblon ligand derived from Thalidomide with a linker commonly used in PROTAC technology.

Thalidomide-piperidine-CO-piperazine-C-3-Br-Ph 属于 E3 泛素酶配体+连接子偶联物 (E3 Ligase Ligand-Linker Conjugates) 类别。该化合物主要应用于合成 PROTAC SMARCA2 degrader-28。

Thalidomide-piperidine-C2-piperazine-Boc 是一种 E3 连接酶配体-linker 偶联物 (E3 Ligase Ligand-linker conjugate)，由基于 Thalidomide 的 cereblon 配体以及一个 linker 组成，可用于合成 PROTAC。

PROTAC ER Degrader-14 (compound 86) 是一种 PROTAC 类型的 Estrogen Receptor ERR 降解剂，由以下部分组成：E3 泛素连接酶配体 (blue part)(S)-Deoxy-thalidomide、PROTAC Linker (black part) N-Boc-piperazine，以及靶蛋白配体 (red part) ER ligand-6。E3 连接酶加上 Linker 共同构成了 tert-Butyl (S)-4-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)piperazine-1-carboxylate。

Thalidomide-5-piperazine-C-piperidine-CO-C8-NH2 是 E3 泛素连接酶配体-连接子偶联物的一种化学复合物.

Thalidomide-5-piperazine 作为一种PROTAC靶蛋白配体,广泛应用于相关领域.