Pimaricacid has potent anti-atherosclerotic activity with inhibitory action on matrix metalloproteinase-9 production and cell migration in TNF-α±-induced human aortic smooth muscle cells.
Dihydroisopimaricacid activates BK channels alphabeta1, which are large conductance Ca 2+ activated K + channels. This compound directly measures the opening of BKalphabeta1 under a whole-cell voltage clamp.
Levopimaricacid is a plant-derived diterpene resin acid that exhibits multiple beneficial properties. It promotes cancer cell apoptosis, while also possessing anticancer, antioxidant, antibacterial, and cardiovascular activities.
Isopimaricacid is active against MDR and MRSA strains of S. aureus which are becoming increasingly resistant to antibiotics, the minimum inhibitory concentrations (MIC) are 32-64 microg mL . Isopimaricacid is also possible that an antagonistic interacti
Sandaracopimaricacid is an anti-inflammatory diterpenoid compound that effectively reduces the contraction of phenylephrine-induced pulmonary arteries. With an EC50 of 43.93 μM, it exhibits noteworthy anti-inflammatory properties.