oleic acid sodium

Sodium oleate (cis-9-Octadecenoic acid sodium salt) (Oleic acid sodium) 是人脂肪细胞和其他组织中最常见的单不饱和脂肪酸钠盐。Sodium oleate 是一种 Na+ K+ ATP 酶激活剂。

(Rac)-Idroxioleic acid sodium [又称2-Hydroxyoleic acid sodium] 是一类由油酸 (OA) 衍生的化合物，通过与细胞质膜结合，能够改变脂质的组成。此外，该化合物还展现出了抗肿瘤的潜力。

Palmitoleic acid, an ω-7 monounsaturated fatty acid found in macadamia and sea buckthorn oils, enhances both basal and insulin-stimulated glucose uptake, as well as Glut4 protein levels in 3T3-L1 adipocytes at a 200 µM concentration. Ex vivo, at a dosage of 300 mg kg per day, it significantly increases glucose uptake and both aerobic and anaerobic glycolysis, while decreasing de novo fatty acid synthesis and the activity of lipogenic enzymes, specifically ATP citrate lyase (ACL) and glucose-6-phosphate dehydrogenase (G6PDH), in isolated murine adipocytes. Furthermore, the dietary administration of palmitoleic acid at 300 mg kg mitigates high-fat diet-induced insulin resistance and liver inflammation in mice.

9(Z),11(E)-Conjugated linoleic acid is an isomer of linoleic acid that has been found in beef and milk fat.1It binds to peroxisome proliferator-activated receptor α (PPARα; IC50= 140 nM) and activates the receptor in a reporter assay using COS-1 cells expressing mouse PPARα when used at a concentration of 100 μM.29(Z),11(E)-Conjugated linoleic acid inhibits TNF-α-inducedGLUT4expression and increases insulin-stimulated glucose transport in 3T3-L1 adipocytes.3Dietary administration of 9(Z)11(E)-conjugated linoleic acid reduces serum fasting glucose, insulin, and triglyceride levels and decreases white adipose tissue macrophage infiltration inob obmice. It also increases body weight gain and body fat in weanling mice.4[Matreya, LLC. Catalog No. 1278] 1.Shultz, T.D., Chew, B.P., Seaman, W.R., et al.Inhibitory effect of conjugated dienoic derivatives of linoleic acid and β-carotene on the in vitro growth of human cancer cellsCancer Lett.63(2)125-133(1992) 2.Moya-Camarena, S.Y., Heuvel, J.P.V., Blanchard, S.G., et al.Conjugated linoleic acid is a potent naturally occurring ligand and activator of PPARαJ. Lipid Res.40(8)1426-1433(1999) 3.Moloney, F., Toomey, S., Noone, E., et al.Antidiabetic effects of cis-9, trans-11-conjugated linoleic acid may be mediated via anti-inflammatory effects in white adipose tissueDiabetes56(3)574-582(2007) 4.Pariza, M.W., Park, Y., and Cook, M.E.The biologically active isomers of conjugated linoleic acidProg. Lipid Res.40(4)283-298(2001)

Oleic acid (Glycon Wo) 属于天然产物，是一种常见的不饱和脂肪酸，在存在于多种动物、植物的脂肪和油脂中。Oleic acid 是一种 Na+ K+ATP 酶激活剂。

Cardiolipin (16:0 18:1 16:0 18:1) (16:0-18:1 Cardiolipin) sodium 是一种含有饱和棕榈酸和单不饱和油酸的阴离子磷脂。Cardiolipin (16:0 18:1 16:0 18:1) sodium 适用于纳米磷脂盘的合成，并用于原位质谱分析。

1-Oleoyl-2-hydroxy-sn-glycero-3-PG (sodium salt), a lysophospholipid with oleic acid (18:1) at the sn-1 position, finds application in creating micelles, liposomes, and various artificial membranes, notably in lipid-based drug delivery systems.

LBA-3 是一种口服有效的选择性钠偶联柠檬酸转运蛋白SLC13A5抑制剂，IC50为67 nM。LBA-3 可降低油酸和棕榈酸 (OPA) 刺激的AML12细胞、PCN刺激的原代小鼠肝细胞以及小鼠模型中的甘油三酯和总胆固醇水平，且未检测到毒性，并具有血脑屏障通透性。