ind 8

IND8 is a selective and potent α7-nAChR agonist.

XM 412, also known as DMP 450, is an HIV protease inhibitor.

Blonanserin D8 is a deuterium-labeled Blonanserin. Blonanserin (AD-5423) is a dopamine D2 5-HT2 receptor antagonist with an atypical antipsychotic effect.

Teneligliptin D8 a deuterium labeled Teneligliptin (MP-513). Teneligliptin is a potent, orally available, competitive, and long-lasting inhibitor of DPP-4.

Doxazosin D8 (UK 33274 D8) is a deuterium labeled Doxazosin (UK 33274).Doxazosin, a quinazoline derivative, selectively antagonizes postsynaptic AP1 adrenergic receptor.

IND81 is an antiprion agent that works by extending the lives of prion-infected animals.

Norfloxacin-d8 是 Norfloxacin 的氘代化合物。Norfloxacin 的 CAS 号为 70458-96-7。Norfloxacin是广谱抗生素，能通过结合DNA旋转酶抑制革兰氏阳性和阴性菌。

Ofloxacin-d8 是 Ofloxacin 的氘代化合物。Ofloxacin 的 CAS 号为 82419-36-1。Ofloxacin是可抑制细菌DNA旋转酶的一种氟喹诺酮类抗生素。

Levofloxacin-d8 是 Levofloxacin 的氘代化合物。Levofloxacin 的 CAS 号为 100986-85-4。Levofloxacin是合成的氟喹诺酮类抗生素，有抑制细菌DNA旋转酶的超螺旋活性的作用，能阻止DNA复制。

Enoxacin-d8 HCl 是 Enoxacin HCl 的氘代化合物。Enoxacin HCl 的 CAS 号为 74011-31-7。

Bisdesmethoxy Curcumin-d8 是 Bisdesmethoxy Curcumin 的氘代化合物。Bisdesmethoxy Curcumin 的 CAS 号为 33171-05-0。Bisdemethoxycurcumin是姜黄素的天然去甲氧基衍生物，具有抗炎和抗癌活性。

Ciprofloxacin-d8 是 Ciprofloxacin 的氘代化合物。Ciprofloxacin 的 CAS 号为 85721-33-1。Ciprofloxacin是一种有高抗菌活性的氟喹诺酮类抗生素。

Prazosin-d8 是 Prazosin 的氘代化合物。

Rifampicin-d8 是 Rifampicin 的氘代化合物。Rifampicin 的 CAS 号为 13292-46-1。Rifampicin是广谱抗生素，可抵抗细菌病原体以及具有抗流感病毒活性。

Ciprofloxacin-d8 Hydrochloride 是 Ciprofloxacin Hydrochloride 的氘代化合物。Ciprofloxacin Hydrochloride 的 CAS 号为 93107-08-5。Ciprofloxacin hydrochloride是一种高抗菌活性的氟喹诺酮类抗生素。

Sarafloxacin-d8 Hydrochloride 是 Sarafloxacin Hydrochloride 的氘代化合物。Sarafloxacin Hydrochloride 的 CAS 号为 91296-87-6。Sarafloxacin hydrochloride是一种抗菌化合物。

Terazosin-d8 是 Terazosin 的氘代化合物。Terazosin 的 CAS 号为 63590-64-7。

3-Hydroxyterphenyllin is a p-terphenyl fungal metabolite originally isolated from A. candidus that has diverse biological activities, including antioxidant, antiproliferative, antibacterial, and antiviral properties.1,2,3,4 It has a 96% scavenging effect on 2,2-diphenyl-1-picrylhydrazyl radicals when used at a concentration of 100 μg/ml.2 3-Hydroxyterphenyllin inhibits the growth of HeLa cervical, A549 lung, and HepG2 liver cancer cells (IC50s = 23, 36, and 32 μM, respectively), as well as methicillin-resistant S. aureus (MRSA) and V. vulnificus bacteria (MIC = 31 μg/ml for both).3 It also inhibits HIV-1 integrase in both coupled and strand transfer assays (IC50s = 2.8 and 12.1 μM, respectively).4References1. Kurobane, I., Vining, L.C., McInnes, A.G., et al. 3-Hydroxyterphenyllin, a new metabolite of Aspergillus candidus. Structure elucidation by 1H and 13C nuclear magnetic resonance spectroscopy. J. Antibiot. (Tokyo) 32(6), 559-564 (1979).2. Yen, G.-C., Chang, Y.-C., Sheu, F., et al. Isolation and characterization of antioxidant compounds from Aspergillus candidus broth filtrate. J. Agric. Food Chem. 49(3), 1426-1431 (2001).3. Wang, W., Liao, Y., Tang, C., et al. Cytotoxic and antibacterial compounds from the coral-derived fungus Aspergillus tritici SP2-8-1. Mar. Drugs 15(11), E348 (2017).4. Singh, S.B., Jayasuriya, H., Dewey, R., et al. Isolation, structure, and HIV-1-integrase inhibitory activity of structurally diverse fungal metabolites. J. Ind. Microbiol. Biotechnol. 30(12), 721-731 (2003). 3-Hydroxyterphenyllin is a p-terphenyl fungal metabolite originally isolated from A. candidus that has diverse biological activities, including antioxidant, antiproliferative, antibacterial, and antiviral properties.1,2,3,4 It has a 96% scavenging effect on 2,2-diphenyl-1-picrylhydrazyl radicals when used at a concentration of 100 μg/ml.2 3-Hydroxyterphenyllin inhibits the growth of HeLa cervical, A549 lung, and HepG2 liver cancer cells (IC50s = 23, 36, and 32 μM, respectively), as well as methicillin-resistant S. aureus (MRSA) and V. vulnificus bacteria (MIC = 31 μg/ml for both).3 It also inhibits HIV-1 integrase in both coupled and strand transfer assays (IC50s = 2.8 and 12.1 μM, respectively).4 References1. Kurobane, I., Vining, L.C., McInnes, A.G., et al. 3-Hydroxyterphenyllin, a new metabolite of Aspergillus candidus. Structure elucidation by 1H and 13C nuclear magnetic resonance spectroscopy. J. Antibiot. (Tokyo) 32(6), 559-564 (1979).2. Yen, G.-C., Chang, Y.-C., Sheu, F., et al. Isolation and characterization of antioxidant compounds from Aspergillus candidus broth filtrate. J. Agric. Food Chem. 49(3), 1426-1431 (2001).3. Wang, W., Liao, Y., Tang, C., et al. Cytotoxic and antibacterial compounds from the coral-derived fungus Aspergillus tritici SP2-8-1. Mar. Drugs 15(11), E348 (2017).4. Singh, S.B., Jayasuriya, H., Dewey, R., et al. Isolation, structure, and HIV-1-integrase inhibitory activity of structurally diverse fungal metabolites. J. Ind. Microbiol. Biotechnol. 30(12), 721-731 (2003).

2-Methylhexacosane is a saturated hydrocarbon and an insect pheromone.1,2It has been found in the cuticle ofM. dasystomusfemales, but not males, where it contributes to the mating behavior of males, as well as inD. melanogasterfemales where it modulates aggression of males towards females. 2-methylhexacosane has also been found in yellow jacket (V. vulgaris) trail extracts.3 1.Spikes, A.E., Pashen, M.A., Millar, J.G., et al.First contact pheromone identified for a longhorned beetle (Coleoptera: Cerambycidae) in the subfamily PrioninaeJ. Chem. Ecol.36(9)943-954(2010) 2.Fernández, d.l.P., Chan, Y.-B., Yew, J.Y., et al.Pheromonal and behavioral cues trigger male-to-female aggression in DrosophilaPLoS Biol.8(11)e1000541(2010) 3.Steinmetz, I., Schmolz, E., and Ruther, J.Cuticular lipids as trail pheromone in a social waspProc. Biol. Sci.270(1513)385-391(2003)