hydrate

2,2,2-Trichloroethanol 是非经典的 K2P 通道 TREK-1和 TRAAK 的激动剂。

Regadenoson is an A2A adenosine receptor agonist, a coronary vasodilator commonly used in pharmacologic stress testing.

Meclofenamate sodium is a potent non-steroidal anti-inflammatory agent, which can specifically inhibit chemokine-induced human polymorphonuclear leukocyte function: chemotaxis, degranulation, and superoxide anion free radical production.

Cefadroxil is a first generation aminocephalosporin with good patient compliance, a long-acting therapeutic effect, high solubility and relatively broad spectrum of anti-bacterial activity. Cefadroxil is also a substrate of the intestinal peptide transporter PepT1, which is primarily responsible for the drug's uptake across the apical membrane of small intestine.

5'-GTP trisodium salt hydrate, an activator of the signal-transducing G proteins, serves as a precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.

A-317491 sodium salt hydrate is a non-nucleotide P2X3 and P2X2 3 receptor antagonist that inhibits receptor-mediated calcium flux.

BIX-01338 hydrate is an inhibitor of histone lysine methyltransferase.

Geodin hydrate 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T125050，CAS号为 3209-10-7。

Fanapanel hydrate is a highly selective antagonist of AMPA kainate with little activity against NMDA(Ki of 3.2 nM, 100 nM, and 8.5 μM against quisqualate, kainate, and NMDA, respectively).

Zoniporide hydrochloride hydrate is a potent and selective sodium-hydrogen exchanger type 1 (NHE-1) inhibitor. Zoniporide hydrochloride hydrate inhibits human NHE-1 with IC50 of 14 nM.

Ivacaftor hydrate is an orally bioavailable CFTR potentiator. It also is used for cystic fibrosis treatment.

Ribociclib succinate hydrate is a highly specific CDK4 6 inhibitor (IC50s: 10 nM and 39 nM, respectively). It also is over 1,000-fold less potent against the cyclin B CDK1 complex.

Napsagatran hydrate is a novel and specific inhibitor of thrombin.

Pritelivir mesylate hydrate is active against herpes simplex virus types 1 and 2 (IC50: 0.02 μM against HSV1-2). Pritelivir mesylate hydrate is an inhibitor of the viral helicase-primase complex. Pritelivir mesylate hydrate shows antiviral activity in vit

Tecovirimat,(ST-246, SIgA-246) is an inhibitor of p37 envelope proteins used to treat smallpox infection. Tecovirimat is an antiviral drug that is active against orthopoxviruses such as smallpox and is currently undergoing clinical trials. Its role is to

Hydroxypyruvic acid lithium hydrate is an intermediate in the metabolism of serine, glycine, and threonine. It is a substrate for serine-pyruvate aminotransferase and glyoxylate reductase hydroxypyruvate reductase.

Methylbenzethonium chloride hydrate 在化妆品和药品配方中作为防腐剂，有效预防微生物生长，此外，该化合物对细菌、病毒和真菌展示出广泛的抗微生物活性。

UNC0638 hydrate 作为一种化合物，主要通过选择性抑制G9a和GLP组蛋白甲基转移酶达到其生物活性，其半抑制浓度(IC50)分别为15 nM和19 nM。在体外实验中，此化合物有效抑制TNBC（三阴性乳腺癌）细胞的侵袭与迁移。同时，作为EHMT1 2的抑制剂，它能在人红细胞祖细胞的培养中诱导胎儿血红蛋白(HbF)的表达。此外，UNC0638 hydrate 对FMDV（口蹄疫病毒）和VSV（水疱性口炎病毒）均显示出抗病毒活性，展现了其在多种表观遗传和非表观遗传靶标上的高效力和选择性。

Ouabain 是一种心脏类固醇，能够结合 Na(+), K(+)-ATPase 并抑制其活性。该化合物能增强心肌的收缩力，稳定心率，并促进心脏、血管和神经细胞在体外和体内的生长。

bpV(bipy) hydrate 是一种能有效抑制磷酸肌醇 3-磷酸酶 (PTEN) 及蛋白酪氨酸磷酸酶PTP-β和PTP-1B的化合物，其IC50分别为18、60.3和164 nM。

Grazoprevir, a second generation hepatitis C virus protease inhibitor acting at the NS3/4a protease targets, has good activity against a range of hepatitis C virus genotype variants, including some that are resistant to most currently used antiviral medic

Fluconazole 水合物是抗真菌化合物，用于治疗和预防浅表和全身性的真菌感染。

Adenosine kinase is the key metabolizing enzyme regulating cellular adenosine concentrations. Inhibition of adenosine kinase can selectively enhance the protective actions of adenosine during tissue trauma without producing the nonspecific effects associa

Felbamate hydrate is an effective nonsedative anticonvulsant. It is a clinical effect that may be related to the inhibition of N-methyl-D-aspartate.