Conessine hydrobromide is a naturally occurring steroid alkaloid and has been used in traditional herbal medicine as a treatment for amoebic dysentery.
Korepimedoside C, also known as Epimedin I, is a flavonol glycoside derived from the aerial parts of Epimedium koreanum Nakai. Epimedium koreanum Nakai is a renowned Chinese herbal medicine that has been extensively studied for its potential in addressing impotence, osteoporosis, immune suppression, and cardiovascular diseases.
Dehydroandrographolide succinate (potassium sodium salt), derived from the herbal medicine Andrographis paniculata (Burm f) Nees, is a versatile compound highly utilized for the treatment of viral pneumonia and viral upper respiratory tract infections due to its potent immunostimulatory, anti-infective, and anti-inflammatory properties.
Kadsurenone is a platelet-activating factor receptor antagonist from Chinese herbal plant, haifenteng. It is a useful and promising treatment strategy for breast cancer bone metastases by blocking the PAF PTAFR signaling pathway.
SDB-006, a cannabimimetic indole, exhibits affinity for central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors, with EC50 values of 19 nM and 134 nM, respectively. This compound emerged from investigations into JWH 018 adamantyl carboxamide, a related substance known for its illicit sale in herbal mixes. SDB-006 is designated exclusively for research and forensic applications.
Cannabipiperidiethanone, a synthetic cannabinoid structurally similar to JWH 250 and AM2233, has been detected in prohibited herbal blends in Japan. It exhibits affinity for CB1 and CB2 receptors with IC50 values of 591 nM and 968 nM, respectively. Compared to JWH 250, its affinities for CB1 and CB2 receptors are 2.3- and 9.4-fold lower, and 13- and 70-fold lower than (R)-(+)-WIN 55,212-2, respectively. Cannabipiperidiethanone is designated for forensic and research purposes only.