glycolipid

α-Galactosylceramide (KRN7000) 是一种具有抗肿瘤和免疫刺激作用的合成糖脂。它是一种高效的 NKT 细胞激动剂，可与 CD1d 有效结合。它与 CD1d 的复合物可与 NKT 细胞的 T 细胞抗原受体结合。

Glycolipids are lipids with a carbohydrate attached by a glycosidic (covalent) bond. Their role is to maintain the stability of the cell membrane and to facilitate cellular recognition, which is crucial to the immune response and in the connections that allow cells to connect to one another to form tissues.

Gingerglycolipid B 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T124005，CAS号为 88168-90-5。

Gingerglycolipid A is a monoacyldigalactosyl glycerol.

6,6′-Trehalose dioleate（6,6′-TDO）是一种被广泛用于mRNA体内外递送的糖脂化合物。它能高效包裹流感A病毒血凝素A（HA）编码的mRNA，在脂质纳米粒子（LNPs）中使用，用于增强隔离小鼠脾细胞分泌Ifn-γ, Il-2和Tnf-α。在肌肉注射进入小鼠体内后，包含6,6′-TDO的LNPs主要在肝脏与脾脏中集中。区别于未含6,6′-TDO的LNP配方，这种LNPs不会引起血清中血尿素氮（BUN）、乳酸脱氢酶（LDH）、肌钙蛋白I、丙氨酸氨基转移酶（ALT）、及天门冬氨酸氨基转移酶（AST）水平的改变。此外，该LNPs还能提升小鼠血清中IgG1与IgG2a抗体的滴度。

L 681217 is a glycolipid-type antibiotic related to the efrotomycin class. L-681217 inhibits bacterial protein synthesis at the elongation stage. L 681217 shows broad-spectrum antibiotic activity against Gram-positive and Gram-negative bacteria.

L 644257 is a synthetic glycolipid for study liposomes in vivo.

Woodrosin I is a glycolipid.

Ganglioside GM1 asialo is a component of cellular lipid rafts and can be formed by the cleavage of the sialic acid residue from ganglioside GM1 by neuraminidase. Ganglioside GM1 asialo is a glycolipid receptor for P. aeruginosa flagellin and stimulates defensive responses in host cells, including extracellular ATP release, calcium mobilization, and ERK1/2 phosphorylation when stimulated by flagellin and an anti-ganglioside GM1 asialo antibody. The percentage of ganglioside GM1 asialo-positive natural killer (NK) and CD8+ T cells in lung is increased in a mouse model of respiratory syncytial virus (RSV) infection compared with healthy animals. Depletion of ganglioside GM1 asialo-positive NK and T cells reduces IFN-γ levels in the lung, reduces weight loss, and increases lung viral load in RSV-infected mice. Ganglioside GM1 asialo mixture contains ganglioside GM1 asialo molecular species with C18:1 and C20:1 sphingoid backbones.

Tetracosanoyl-sulfatide is an endogenous sulfated glycolipid, which are also known as sulfatides . Tetracosanoyl-sulfatide is the major sulfatide in mature myelin in the central and peripheral nervous systems. Levels of Tetracosanoyl-sulfatide are elevated in plasma derived from patients with metachromatic leukodystrophy, a disorder characterized by arylsulfatase A deficiency, leading to sulfatide accumulation. Unlike C24:1 3'-sulfo galactosylceramide, it does not induce an immune response in mouse splenocytes in vitro.

SQDG 是一种膜脂，头部基团含有糖部分，用于研究结构脂在LNP制剂中的作用。

Lacto-N-fucopentaose II (LNFP II)作为人Lewis血型决定因子的半抗原，其单唾液神经节苷 糖脂以及唾液酰衍生物CA 19-9，都是胆胰恶性肿瘤中的分子肿瘤标记物(TM)。

BAY-R 1005为合成糖脂类似物(GLA)，具有免疫增强作用，能够调控抗体的合成。

10-Methyl palmitic acid methyl ester is a methylated derivative of fatty acid methyl ester, identified in glycolipid analogs with cyclitol from P. crassa. [Matreya, LLC. Catalog No. 1792]

AGI-134是一种全合成的α-Gal糖脂，激发CD8+ T细胞介导的免疫，诱导肿瘤细胞破坏和吞噬作用。

Trehalose 6,6'-dimycolate（Cord Factor）为结核分枝杆菌细胞壁组成的海藻糖 6,6'-二霉酸酯，主要通过模拟结核分枝杆菌(MTB)诱发的炎症和肉芽肿。此外，Trehalose 6,6'-dimycolate在防止巨噬细胞介导的杀伤作用中发挥重要角色，还可通过抑制有效的抗原呈递和减少保护性T细胞反应的生成，增强结核杆菌的生存能力。

Trehalose-6,6'-dibehenate 是一种具有生物活性的糖脂，适用于制备疫苗佐剂。

GCS-12 作为一种 Th1 2 平衡的磺酰胺糖脂,主要通过增强与CD1d的相互作用来发挥作用.该化合物能激活自然杀伤 T 细胞 (NKT cell),诱导它们分泌细胞因子IFN-γ和IL-4,进而在小鼠体内展示出显著的免疫调节和抗肿瘤活性.

Octadecylthioethyl 4-O-α-D-galactopyranosyl-β-D-galactopyranoside 是一种糖脂受体，适用于研究脂质调节机制。