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TargetMol产品目录中 "

g36

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  • 抑制剂&激动剂
    35
    TargetMol | Inhibitors_Agonists
  • 重组蛋白
    2
    TargetMol | Recombinant_Protein
  • PROTAC
    26
    TargetMol | PROTAC
  • 检测抗体
    7
    TargetMol | Antibody_Products
  • G36
    G-36
    T227941392487-51-2In house
    G36是一种细胞可渗透的G 蛋白偶联雌激素受体(GPER GPR30)的非甾体拮抗剂。G36抑制17β-雌二醇或GPER 选择性激动剂G-1的激活(IC50分别为112和165 nM)。G36对ERα或ERβ均无可检测的结合活性。G36通过GPER 阻断由雌激素触发的PI3K 的激活或钙动员,并且它通过雌激素或G-1而不是通过EGF 抑制ERK 的激活。
    • ¥ 348
    现货
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  • DSPE-PEG36-mal
    T17857
    DSPE-PEG36-mal is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
    • 待询
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  • Mal-PEG36-NHS ester
    T18282
    Mal-PEG36-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
    • 待询
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  • N-Boc-PEG36-alcohol
    T18404
    N-Boc-PEG36-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
    • 待询
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  • ZG36
    T80737
    ZG36是一种人类Caseinolytic protease P(ClpP)激动剂,具有非选择性地降解呼吸链复合物和减少线粒体DNA的能力,从而导致线粒体功能衰竭及白血病细胞死亡。此外,ZG36能够抑制异种移植小鼠模型中急性髓细胞性白血病的发展。
    • 待询
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  • Amino-PEG36-Boc
    T17431
    Amino-PEG36-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
    • 待询
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  • Azido-PEG36-Boc
    T17512
    Azido-PEG36-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
    • 待询
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  • Biotin-PEG36-PFP ester
    T17578
    Biotin-PEG36-PFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
    • 待询
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  • m-PEG36-OH
    T18195
    m-PEG36-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
    • 待询
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  • Boc-NH-PEG36-CH2CH2COOH
    T17678
    Boc-NH-PEG36-CH2CH2COOH is a polyethylene glycol (PEG)-based PROTAC linker employed for the synthesis of PROTACs[1].
    • 待询
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  • m-PEG36-Mal
    T18194
    m-PEG36-Mal is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
    • 待询
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  • m-PEG36-azide
    T18192
    m-PEG36-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
    • 待询
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  • Fmoc-N-PEG36-acid
    T17962
    Fmoc-N-amido-PEG36-acid is a polyethylene glycol (PEG)-based linker utilized in PROTAC synthesis. It has been designed specifically for constructing PROTACs, which are bifunctional molecules capable of recruiting target proteins to an E3 ubiquitin ligase for degradation[1].
    • 待询
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  • OPSS-PEG36-acid
    T18510
    OPSS-PEG36-acid is a 36-unit PEG linker amenable to cleavage, specifically designed for the synthesis of antibody-drug conjugates (ADCs)[1].
    • 待询
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  • Amino-PEG36-alcohol
    T17430
    Amino-PEG36-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
    • 待询
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  • APN-PEG36-tetrazine
    T77836
    APN-PEG36-tetrazine是APN-PEG4-tetrazine的类似物,后者作为具有可降解(cleavable)特性的含四个单元PEG的ADC linker,应用于抗体偶联活性分子(ADC)的合成。
    • 待询
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  • Amino-PEG36-CONH-PEG36-acid
    T17433
    Amino-PEG36-CONH-PEG36-acid is a polyethylene glycol (PEG)-based linker with amino and carboxylic acid functionalities. It finds utility in the synthesis of proteolysis targeting chimeras (PROTACs)[1].
    • 待询
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  • Azido-PEG36-alcohol
    T17511
    Azido-PEG36-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
    • 待询
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  • m-PEG36-alcohol
    T18190
    m-PEG36-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
    • 待询
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  • Biotin-PEG36-acid
    T17577
    Biotin-PEG36-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
    • 待询
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  • Amino-PEG36-CH2-Boc
    T17432
    Amino-PEG36-CH2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
    • 待询
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  • Azido-PEG36-acid
    T17510
    Azido-PEG36-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
    • 待询
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  • m-PEG36-Br
    T18193
    m-PEG36-Br is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
    • 待询
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  • m-PEG36-amine
    T18191
    m-PEG36-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
    • 待询
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