e 1

Estrone (Aquacrine) 是内源性雌激素的主要代表，由多种组织产生，尤其是脂肪组织。它是脂肪细胞中雄烯二酮芳构化过程的结果。

Mogroside I E1 是三萜糖苷，是非糖类甜味剂。其中 Mogroside 的甜度比蔗糖高，具有抗氧化，抗糖尿病和抗癌特性。

Resolvin E1 is an effective endogenous pro-resolving mediator of inflammation. Resolvin E1 has unique counterregulatory actions that inhibit PMN transendothelial migration. Resolvin E1 also acts as an effective inhibitor of leukocyte infiltration, dendrit

13,14-dihydro-15-keto Prostaglandin E1 可抑制 ADP 诱导的人离体富血小板血浆中的血小板聚集（IC50=14.8 μg mL），也是 PGE1 代谢物。

8-iso Prostaglandin E1 能引起犬肺静脉中的痉挛，还能够起到血管舒张作用。

16,16-dimethyl Prostaglandin E1 是 PGE1 (T1626) 类似物，可诱导支气管收缩和血管平滑肌收缩，并抑制吲哚美辛诱导的细胞伸长。

1a,1b-dihomo Prostaglandin E1 是一类前列腺素化合物。

13,14-dihydro Prostaglandin E1 (13,14-dihydro PGE1) is a biologically active metabolite of PGE1 with comparable potency to the parent compound. It is an inhibitor of ADP-induced platelet aggregation in human PRP and washed platelets with IC50 values of 31 and 21 nM, respectively. 13,14-dihydro PGE1 is a slightly more potent inhibitor of ADP-induced human platelet aggregation than PGE1 which has an IC50 value of 40 nM. Also, 13,14-dihydro PGE1 was shown to activate adenylate cyclase in NCB-20 hybrid cells with a Kact value of 668 nM.

19(R)-hydroxy Prostaglandin E1 是 EP1 和 EP3 受体亚型的激动剂，并对平滑肌表现出收缩活性，也是灵长类动物精液中的主要前列腺素。

OVA-E1 peptide, a variant antagonist of SIINFEKL [OVA (257-264)], elicits comparable activation of the p38 and JNK cascades in both mutant and wild-type thymocytes.

Schidigerasaponin E1 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T125156，CAS号为 266998-23-6。

Theasaponin E1，一种可从茶籽分离的茶皂苷，对人肿瘤细胞系K562和HL60展示了抗肿瘤潜能。此外，Theasaponin E1具备醌还原酶(QR)诱导活性，有助于作为抗癌预防药物的研究。

Polymyxin E1，是一种肽类抗生素，也是原初从B. polymyxa分离得到的阳离子脂肽抗生素colistin的主要成分。对P. aeruginosa和E. coli具有活性（MICs分别为2和0.8 µg ml）。

Prostaglandin E1 (PGE1), synthesized through cyclooxygenase-mediated metabolism of dihomo-γ-linolenic acid (DGLA), functions by inhibiting platelet aggregation (IC50= 40 nM) and enhancing vasodilation. Its analog, 13,14-dihydro-16,16-difluoro PGE1, and the metabolite, 13,14-dihydro PGE1, both retain similar anti-aggregatory properties to the original compound. The inclusion of two electron-withdrawing fluorine atoms in 13,14-dihydro-16,16-difluoro PGE1 is believed to increase molecular stability and potentially extend bioavailability by resisting hydrolytic degradation.

13,14-dihydro-15(R)-Prostaglandin E1 (13,14-dihydro-15(R)-PGE1)为13,14-二氢-PGE1的同分异构体，特点在于其C-15位的羟基呈R构型，非自然形态。

13,14-Dihydro-19(R)-hydroxy Prostaglandin E1 (13,14-dihydro-19(R)-hydroxy PGE1) is posited as a theoretical metabolite resulting from the action of ω-1 hydroxylase on 13,14-dihydro PGE1. Its biosynthesis and biological activity remain unreported in scientific literature.

Prostaglandin E1 ethanolamide，前列腺素E1 (PGE1) 的类似物，可能有效抑制GLI2诱导的靶基因表达（包括Gli1和Ptch1）和肿瘤生长。

Prostaglandin E1 (PGE1), though not predominantly found in nature, plays a significant role in clinical treatments, addressing conditions such as peripheral occlusive vascular disease, erectile dysfunction, and neonatal cardiology issues. The metabolism of PGE1 primarily begins with the oxidation at C-15, producing 13,14-dihydro-15-keto PGE1 as its major metabolite. Alternatively, inhibiting this pathway or overwhelming it with too much PGE1 could potentially enhance the production of 2,3-dinor metabolites, like 2,3-dinor PGE1, though their biological activities remain unreported. Cayman Chemical stands out as a prominent provider of prostaglandins and their metabolites, uniquely manufacturing 2,3-dinor PGE1.

Tetranor-Prostaglandin E1 (tetranor-PGE1), a metabolite of PGE1 and PGE2, undergoes formation through β-oxidation.

Luminacin E1 对毛细血管形成具有强效抑制作用 (IC50 < 0.1 μg/mL)。

Japondipsaponin E1 是一种天然化合物，可作为天然产物对照品，其 CAS 号为 175586-66-0。

Anemarsaponin E1可以从桂枝芍药知母汤（GSZD）中分离得到，可用于类风湿性关节炎（RA）、痛风、骨关节炎等疾病的研究。

Ketoconazole Intermediate 1e ((cis-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate) 是一种酮康唑中间体。

(S)-4-Hydroxy-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65610，CAS号为 154127-42-1。