dihydroxyacetone phosphate

Dihydroxyacetone phosphate (DHAP) is a crucial intermediate in lipid biosynthesis and glycolysis, participating in numerous metabolic pathways, including the Calvin cycle and glycolysis in plants.

Dihydroxyacetone phosphate hemimagnesium salt hydrate 也称为磷酸二羟基丙酮或 3-羟基-2-氧代丙基磷酸。 Dihydroxyacetone phosphate hemimagnesium salt hydrate 存在于从细菌到人类的所有生物中。在人类体内， Dihydroxyacetone phosphate hemimagnesium salt hydrate参与许多酶促反应。 Dihydroxyacetone phosphate hemimagnesium salt hydrate 已被研究用于治疗淋巴瘤、大细胞淋巴瘤、弥漫性淋巴瘤。

Dihydroxyacetone phosphate dilithium (DHAP) 用于研究果糖代谢、丙糖和糖基化，并在三碳糖库代谢及其生理和物理过程中的应用。

sn-Glycerol 3-phosphate 是一种人内源性化合物，由NADH 还原磷酸二羟基丙酮而产生。

sn-Glycerol 3-phosphate lithium is synthesized via the cytosolic glycerol 3-phosphate dehydrogenase pathway. This process involves the conversion of dihydroxyacetone phosphate to sn-Glycerol 3-phosphate using NADH, which is generated during glycolysis.

Phosphatidic acid is a phospholipid and an intermediate in glycerolipid biosynthesis. It is a transient intermediate in the synthesis of various phospholipid species that is synthesized de novo in cells via multiple routes, including the glycerol-3 phosphate and dihydroxyacetone phosphate pathways, enzymatic conversion of phosphatidylcholine by phospholipase D, and acetylation of lysophosphatidic acid by lysoPA-acyltransferase, among others. It has roles in shaping cellular membranes, cellular signaling, vesicle fission and fusion, as well as mitochondrial division and fusion. It stimulates respiratory burst in neutrophils independent of diacylglycerol and activates monoacylglycerol acyltransferase, phospholipase C (PLC), Ras, and phosphatidylinositol 4-phosphate (PIP4) kinase in several cell lines. Phosphatidic acids (egg) is a mixture of phosphatidic acids isolated from chicken egg with fatty acids of variable chain lengths.

D-Sedoheptulose-7-phosphate is an intermediate in the pentose phosphate pathway. [1] [2] In this pathway, transaldolase catalyzes the transfer of a three carbon dihydroxyacetone moiety from D-sedoheptulose-7-phosphate to glyceraldehyde-3-phosphate to generate D-fructose-6-phosphate . D-Sedoheptulose-7-phosphate is also an intermediate in carbon fixation in photosynthetic organisms, as well as in the biosynthesis of lipopolysaccharide, amino acids, secondary metabolites, and antibiotics. [3]

Aldolase 是一种糖酵解酶，也是 vATP 酶复合物的组成部分。Aldolase 可使 1，6-二磷酸果糖分解成二羟基丙酮和 3-磷酸甘油醛。

Glycerol phosphate dehydrogenase 催化磷酸二羟丙酮转化为 α-甘油磷酸。

Triosephosphate isomerase (TPI) 是一种能够在糖酵解过程中快速转换磷酸二羟丙酮(dihydroxyacetone phosphate)与D: -甘油醛-3-磷酸(D: -glyceraldehyde-3-phosphate)的酶。其催化位点位于酶的二聚体界面。

Glycerol-3-phosphate dehydrogenase, Saccharomyces cerevisiae 是一种在酵母Saccharomyces cerevisiae中发挥关键作用的酶，主要参与甘油代谢及能量产生过程。它催化Glycerol-3-phosphate (G3P)氧化成磷酸二羟丙酮 (DHAP)，并作为该菌种生物合成甘油的限速酶，调节甘油的生成与积累，有利于Saccharomyces cerevisiae应对高渗透压环境。此外，该酶亦可用于代谢工程领域的研究。