deoxycytidine triphosphate

Deoxycytidine triphosphate 是一种核苷三磷酸，是合成 DNA 的原料，可用于实时荧光定量 PCR、cDNA 合成和 DNA 测序。

Deoxycytidine triphosphate (dCTP; 2′-Deoxycytidine-5′-triphosphate) disodium 是一种用于生命科学研究的生化试剂，作为重要的生物材料或有机化合物。

Deoxycytidine triphosphate trisodium salt (2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI) 是可用于 DNA 合成的核苷三磷酸，可用于实时荧光定量 PCR、cDNA 合成和 DNA 测序。

Fludarabine Phosphate (NSC 312887 Phosphate) 是一种腺苷和脱氧腺苷类似物，与 dATP 竞争，并入到 DNA，可以抑制 DNA 聚合酶 α、核糖核苷酸还原酶和 DNA 引发酶，从而中断 DNA 合成并抑制肿瘤细胞生长。

​Menthyl acetate 是一种可有效增强 5-氨基乙酰丙酸 (ALA) 皮肤渗透的 L-薄荷醇衍生物。​

Clofarabine-5'-triphosphate 是Clofarabine 经由脱氧胞苷激酶 (dCK) 磷酸化形成的代谢产物。其通过抑制 DNA 合成及 DNA 修复机制，在癌细胞中展现出细胞毒性效果。

Clofarabine-5'-diphosphate (Clofarabine-DP) 是 Clofarabine 经脱氧胞苷激酶 (dCK) 磷酸化后的代谢产物。Clofarabine-5'-diphosphate 还能继续磷酸化生成 Clofarabine-5'-triphosphate，在癌细胞中通过阻碍 DNA 合成和 DNA 修复展现出细胞毒性。

Clofarabine-5'-diphosphatetrisodium (Clofarabine-DP trisodium) 是 Clofarabine-5'-diphosphate 的钠盐。Clofarabine 经脱氧胞苷激酶 (dCK) 磷酸化后生成 Clofarabine-5'-diphosphate trisodium，这个代谢产物能够进一步被磷酸化为 Clofarabine-5'-triphosphate，并在癌细胞中通过抑制 DNA 合成及 DNA 修复显现细胞毒性。

3'-Deoxyuridine-5'-triphosphate (3'-dUTP) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II. 3'-Deoxyuridine-5'-triphosphate strongly and competitively inhibits the incorporations of UTP into RNA with a Ki value of 2.0 μM[1]. 3'-Deoxyuridine-5'-triphosphate (3'-dUTP) is synthesized starting from cordycepin in good yield. 3'-Deoxyuridine-5'-triphosphate strongly and competitively inhibits the incorporations of UTP into RNA by the RNA polymerases. 3'-Deoxyuridine-5'-triphosphate will be useful in studies at the molecular level on the relationship of template and substrate in RNA synthesis with chromatin, isolated nuclei or permeable cells, because it does not have any effect on poly (rA) synthesis[1]. [1]. M Saneyoshi, et al. Inhibitory Effects of 3'deoxycytidine 5'-triphosphate and 3'-deoxyuridine 5'-triphosphate on DNA-dependent RNA Polymerases I and II Purified From Dictyostelium Discoideum Cells. Nucleic Acids Res. 1981 Jul 10;9(13):3129-38.

2'-Deoxycytidine 是由胞嘧啶和脱氧核糖组成的DNA的主要核苷之一，抑制溴脱氧尿苷 (Brdu) 的生物效应。核苷仅由与嘌呤或嘧啶碱相连的戊糖组成，没有磷酸基团。当N1与脱氧核糖的C1连接时，由胞嘧啶和脱氧核糖形成脱氧核苷和核苷酸；脱氧胞苷单磷酸(dCMP)，脱氧胞苷二磷酸(dCDP)，脱氧胞苷三磷酸(dCTP)。CTP是RNA(核糖核酸)中胞苷的来源，脱氧胞苷三磷酸(dCTP)是DNA(脱氧核糖核酸)中脱氧胞苷的来源。

Fazarabine, also known as Kymarabine, is an orally-active pyrimidine analogue of an aza-substituted cytidine in which the ribose moiety is replaced by an arabinose sugar. Similar in action to cytarabine, fazarabine is phosphorylated by deoxycytidine kinase to a triphosphate form which competes with thymidine for incorporation into DNA; its incorporation into DNA inhibits DNA synthesis, resulting in tumor cell death and tumor necrosis. The presence of deoxycytidine kinase in a tumor is a determinant of tumor sensitivity to this drug.

Sp-2'-Deoxycytidine-5'-O-(1-thiotriphosphate) (Sp-dCTP-α-S) 是含硫核苷酸衍生物 dCTP-α-S 的异构体。它抑制解氧核苷酸三磷酸三磷酸水解酶 SAMHD1（Ki = 6.3 µM）。

Cyclopentenylcytosine（CPC）是一种核苷类似物，通过抑制CTP合成酶来降低白血病细胞中的胞苷三磷酸（CTP）和脱氧胞苷三磷酸（dCTP）水平。此外，Cyclopentenylcytosine 促进 1-β-D-阿拉伯核糖甘露苷胞苷(araC)的磷酸化并增加其插入DNA的活性。Cyclopentenylcytosine 以浓度（50-300 nM）和时间依赖（8-16小时）的方式诱导人T淋巴细胞系MOLT-3的凋亡和坏死。Cyclopentenylcytosine与araC联合使用可以增强对凋亡和坏死的诱导作用及其在T淋巴母细胞中的细胞毒性。