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  • 抑制剂&激动剂
    53
    抑制剂&激动剂
  • 多肽
    5
    多肽
  • PROTAC
    20
    PROTAC
  • 天然产物
    2
    天然产物
  • 分子与细胞研究
    9
    分子与细胞研究
  • 标准品
    1
    标准品
  • ADC/ADC相关
    34
    ADC/ADC相关
  • 2-(Hydroxymethyl)anthraquinone
    2-羟甲基蒽醌
    TN121317241-59-7
    2-(Hydroxymethyl)anthraquinone 是光可清除保护基团,在结构上可以阻碍性信息素释放。
    • ¥ 156
    现货
    规格
    数量
  • Fmoc-Ala-Ala-Asn(Trt)-OH
    T179461951424-92-2
    Fmoc-Ala-Ala-Asn(Trt)-OH 是一种可切割的 ADC 接头,用于抗体-药物偶联物。
    • ¥ 541
    现货
    规格
    数量
    TargetMol | Inhibitor Sale
  • BDP FL DBCO
    BDP FL-二苯并环辛炔
    T145162093197-94-3
    BDP FL DBCO 是抗体-药物偶联物(ADC)合成中关键的可切割连接子分子。该分子可使细胞毒药物与抗体发生共价结合,从而实现靶向递送,其可切割的特性可实现药物的可控释放,从而优化 ADC 在肿瘤学研究中的药效学性能。
    • ¥ 635
    现货
    规格
    数量
  • Boc-Cystamine
    T14724485800-26-8
    Boc-Cystamine is a cleavable linker vital in ADC synthesis. Boc-Cystamine joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
    • ¥ 913
    5日内发货
    规格
    数量
  • m-PEG8-Amine
    T15927869718-81-0
    m-PEG8-Amine is a cleavable linker vital in ADC synthesis. m-PEG8-Amine joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
    • 待询
    规格
    数量
  • Ala-Ala-Asn-PAB
    丙氨酰-丙氨酰-天冬酰胺-PAB
    T173652149584-00-7
    Ala-Ala-Asn-PAB 是一种可切割多肽连接臂,用于抗体-药物偶联物(ADC)的合成,可改善细胞毒性药物的理化性质及毒性特征,并通过形成稳定的肽-药物偶联体实现可控释放。
    • ¥ 1300
    现货
    规格
    数量
  • Alkyne-PEG4-SS-PEG4-alkyne
    T17386
    Alkyne-PEG4-SS-PEG4-alkyne is an eight-unit polyethylene glycol (PEG) linker, designed for antibody-drug conjugates (ADCs) synthesis, that can be cleaved. This linker serves as a connection between the antibody and the drug, allowing for controlled release upon specific conditions [1].
    • 待询
    规格
    数量
  • Azidoethyl-SS-propionic acid
    T175242228857-32-5
    Azidoethyl-SS-propionic acid is an ADC linker, specifically designed for the synthesis of antibody-drug conjugates (ADCs)[1]. It possesses cleavable properties, allowing for the controlled release of drug payloads.
    • 待询
    4-6周
    规格
    数量
  • BCN-SS-amine
    T175391435784-65-8
    BCN-SS-amine is a cleavable linker vital in ADC synthesis. BCN-SS-amine joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
    • 待询
    规格
    数量
  • BCN-SS-NHS
    T17540
    BCN-SS-NHS is a cleavable linker vital in ADC synthesis. BCN-SS-NHS joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
    • 待询
    规格
    数量
  • DBCO-SS-amine
    T178122742923-58-4
    DBCO-SS-amine is a cleavable linker vital in ADC synthesis. DBCO-SS-amine joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
    • 待询
    规格
    数量
  • DMAC-PDB
    T17835663599-04-0
    DMAC-PDB is a cleavable linker vital in ADC synthesis. DMAC-PDB joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
    • 待询
    规格
    数量
  • DMAC-SPP
    T17836663599-10-8
    DMAC-SPP is a cleavable linker vital in ADC synthesis. DMAC-SPP joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
    • 待询
    规格
    数量
  • Gly-Gly-Gly-PEG4-methyltetrazine
    甘氨酰-甘氨酰-甘氨酸-四聚乙二醇-甲基四嗪
    T179882353409-82-0
    Gly-Gly-Gly-PEG4-methyltetrazine 是一种可裂解的四单元 PEG 基抗体–药物偶联物(antibody–drug conjugate,ADC)连接子,专门设计用于实现高效偶联和可控的药物载荷释放。该连接子广泛应用于 ADC 的合成与优化,可实现精确的生物偶联,改善药代动力学性能,并提高靶向药物递送研究中的治疗指数。
    • ¥ 567
    现货
    规格
    数量
  • Methyltetrazine-PEG4-oxyamine
    T18350
    Methyltetrazine-PEG4-oxyamine is a 4-unit polyethylene glycol (PEG) linker employed in the synthesis of antibody-drug conjugates (ADCs), which are extensively used for targeted drug delivery [1]. This cleavable linker offers a means to efficiently attach drugs to antibodies and facilitate their controlled release at the target site.
    • 待询
    规格
    数量
  • NO2-SPDMV
    T18505663598-98-9
    NO2-SPDMV is a cleavable linker vital in ADC synthesis. NO2-SPDMV joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
    • 待询
    规格
    数量
  • PC DBCO-PEG3-biotin
    T18521
    PC DBCO-PEG3-biotin is a trimeric polyethylene glycol (PEG) linker, specifically designed for antibody-drug conjugate (ADC) synthesis, with a cleavable moiety consisting of a dibenzocyclooctyne (DBCO) group and a biotin molecule. This linker provides a platform for the efficient attachment of drugs to antibodies, facilitating the targeted delivery and controlled release of therapeutic agents in ADCs[1].
    • 待询
    规格
    数量
  • PC Mal-NHS carbonate ester
    T185221408057-91-9
    PC Mal-NHS carbonate ester is a cleavable linker specifically designed for the synthesis of antibody-drug conjugates (ADCs)[1]. This chemical compound plays a crucial role in facilitating the conjugation of drugs to antibodies, enabling targeted delivery and enhanced efficacy of therapeutic agents. Its unique carbonate ester structure allows for efficient cleavage in the targeted environment, ensuring the controlled release of the drug payload. Its application in ADC synthesis highlights its importance in the development of innovative and targeted cancer therapies.
    • 待询
    规格
    数量
  • PPC-NHS ester
    2,5-Dioxopyrrolidin-1-yl 3-(pyridin-2-yldisulfanyl)butanoate
    T18559107348-47-0
    PPC-NHS ester is a cleavable linker vital in ADC synthesis. PPC-NHS ester joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
    • ¥ 492
    5日内发货
    规格
    数量
  • sulfo-SPDB
    T187321193111-39-5
    sulfo-SPDB is a cleavable linker vital in ADC synthesis. sulfo-SPDB joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
    • 待询
    规格
    数量
  • TCO-SS-amine
    T18786
    TCO-SS-amine is a cleavable linker vital in ADC synthesis. TCO-SS-amine joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
    • 待询
    规格
    数量
  • (2-pyridyldithio)-PEG1-hydrazine
    (2-pyridyldithio)-PEG1-hydrazine
    T38503111625-28-6
    (2-Pyridyldithio)-PEG1-hydrazine is a one-unit cleavable polyethylene glycol (PEG) linker specifically designed for the synthesis of antibody-drug conjugates (ADCs). This linker offers the advantage of controlled release of the drug payload from the ADC construct. It is utilized in the conjugation process between the antibody and the cytotoxic drug, enabling the targeted delivery of the drug to cancer cells. The (2-pyridyldithio) group of this linker provides stability during circulation in the bloodstream, while the hydrazine moiety allows for efficient drug release at the tumor site. Overall, the (2-pyridyldithio)-PEG1-hydrazine linker serves as a valuable tool in the development of targeted chemotherapeutic agents for cancer treatment.
    • ¥ 497
    5日内发货
    规格
    数量
  • SPDP-sulfo
    T38597121115-30-8
    SPDP-sulfo is a cleavable linker vital in ADC synthesis. SPDP-sulfo joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
    • ¥ 10600
    待询
    规格
    数量
  • Biotin-sar-oh
    T39023154024-76-7
    Biotin-sar-oh is a cleavable linker vital in ADC synthesis. Biotin-sar-oh joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
    • 待询
    规格
    数量