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BnO-PEG1-CH2CO2tBu is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Amino-PEG4-(CH2)3CO2H is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Propargyl-PEG4-CH2CO2-NHS is a PEG derivative containing a propargyl group and an NHS group. The hydrophilic PEG spacer increases solubility in aqueous media.

Azido-PEG5-CH2CO2-NHS is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Boc-Aminooxy-PEG4-CH2CO2H is a polyethylene glycol (PEG) derivative serving as a PROTAC linker for the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Azido-PEG5-CH2CO2-PFP is a polyethylene glycol (PEG) and Alkyl ether-based linker compound. It serves as a key component in the synthesis of proteolysis-targeting chimeras (PROTACs), a class of molecules used for targeted protein degradation[1].

Azido-PEG1-CH2CO2-NHS is an alkyl ether-based linker used for the synthesis of PROTACs[1].

Stearic acid-PEG-CH2CO2H (MW 5000) 是一种两亲性 PEG 聚合物，能够在水溶液中自组装成胶束。硬脂酸的脂肪链适合用于包封或聚集疏水性药物，而 PEG 链则增强了聚合物的全面溶解性。仅限试剂级和研究使用。

Stearic acid-PEG-CH2CO2H (MW 3400) 是一种亲脂性硫醇反应性PEG聚合物。硬脂酸部分用于包封疏水性治疗剂，而PEG链提高整体水溶性及生物相容性。在活化剂（如HATU或EDC）存在下，羧酸（-COOH）与胺（-NH2）通过缩合产生稳定的酰胺键。试剂级，仅供研究使用。

Azido-PEG5-CH2CO2H is a cleavable 5-unit PEG ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs)[1].

Azido-PEG3-CH2CO2Me is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Pomalidomide-PEG3-CO2H (Thalidomide-NH-PEG3-propionic acid) 是一种由 E3 连接酶配体和连接体组成的偶联物，结合了基于 Thalidomide 的 Cereblon 配体和 3 个单元 PEG Linker。

Stearic acid-PEG-CH2CO2H (MW 1000) 是一种两亲性 PEG 聚合物，能在水溶液中形成胶束，适用于药物递送纳米颗粒。其末端羧基在 HATU EDC 活化剂存在下，通过缩合反应可与胺发生反应。仅限于试剂级研究使用。

1-Nonadecanol 是一种 Heracleum thomsonii 的超临界二氧化碳精油的成分，也是 Neotinea ustulata 的重要香气化合物。

(S,R,S)-AHPC-Me-CO-CH2-PEG3-NH2 is a synthetic E3 ligase ligand-linker conjugate comprised of a VHL ligand and a linker. It is utilized in PROTAC BRD4 Degrader-5 and PROTAC BRD4 Degrader-5-CO-PEG3-N3.

2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-Exatecan 作为 ADC 中的药物-linker 偶联物，包含一个可裂解的 linker 和 Exatecan。此偶联物能够与抗 Her3 抗体进行连接。

AZD-CO-C2-Ph-amido-Ph-azide is an alkyl chain-derived PROTAC linker suitable for PROTACs synthesis[1].

2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-(5-Cl)-Exatecan 是一种用于 ADC 的药物-linker 偶联物，由 linker 和 Exatecan 组成。

Thalidomide-5-piperazine-C-piperidine-CO-C8-NH2 是 E3 泛素连接酶配体-连接子偶联物的一种化学复合物.

(S,R,S)-AHPC-CO-cyclohexane-C2 是一种专用的 E3 泛素连接酶配体-连接子偶联物.

Benzothiazole-CH2(NH-CO-CH2Cl)-CONH-CH2-Ph 作为 E3 泛素连接酶的配体发挥作用.该复合物能够通过其末端接头与蛋白质配体结合,进而生成22-SLF.

HS-(CH2)3CO-L-Ala-D-Ala-L-Ala-NH-CH2-S-(CH2)5-CO-DM 是一种用于抗体偶联药物(ADC)的药物连接体。其中DM代表了maytansinoid组分。

DM-CO-(CH2)5-SMe，一种源自抗体活性分子偶联物(ADC)代谢产物的抗癌剂，对H1703、H1975、COLO704及Colo720E细胞展现出细胞毒性。

(S,R,S)-AHPC-CO-PEG-C2-iodine 是一种E3连接酶(VHL)配体-Linker偶联物，适用于合成PROTAC，如PROTACFAK degrader 1。