biotin-peg-amine

Biotin-PEG-amine (MW 2000) is a polyethylene glycol (PEG) derivative commonly employed as a linker in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Biotin-PEG-amine (MW 3400) is a polyethylene glycol (PEG)-based linker compound utilized for PROTAC synthesis [1].

Biotin-PEG11-amine is a PEG-based linker with biotin labeling which finds application in the synthesis of PROTACs[1].

Biotin-PEG4-amine is a biotinylated, PEGylated amine linker utilized in PROTAC synthesis[1].

Biotin-PEG5-amine is a PEG-based PROTAC linker labeled with biotin. It is utilized in the synthesis of PROTACs, a class of molecules with the ability to target and degrade specific proteins[1].

Biotin-C1-PEG3-C3-amine (TFA) is a polyethylene glycol (PEG) based linker that serves as a crucial component in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Biotin-PEG23-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Biotin-PEG6-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Biotin-PEG8-amine 是一种属于 PEG 类的 PROTAC linker，可用于合成 PROTAC 分子。

Biotin-PEG7-amine is a PEG derivative containing a biotin group and a terminal primary amine group. The hydrophilic PEG spacer increases solubility in aqueous media and increases membrane impermeability of the molecules conjugated to the biotin compound.

NHS-PEG4-biotinidase resistant biotin 是以 NHS 酯为末端的生物素化试剂。其亲水性 PEG 间隔物可以提高其在水性介质中的溶解度。NHS 酯适用于标记蛋白质、胺修饰寡核苷酸及其他含胺分子的一级胺 (-NH2)。

Biotinyl-8-amino-3, 6-dioxaoctanoic acid 是一种生物素化试剂，与PEG链连接，用于增加水溶性。生物素是一种亲和配体，适用于诸如下拉分析或与链霉亲和素蛋白结合等生化应用。在存在活化剂（如HATU）时，其羧基可与含胺分子发生反应。

Mal-Cyclohexyl-PEG3-Biotin 是一种 PEG 连接体，包含马来酰亚胺部分和生物素基团。在 pH 6.5 至 7.5 的范围内，马来酰亚胺能特异性与巯基反应，形成稳定的硫醚键。在 EDC 或 HATU 的作用下，生物素部分可以与胺分子结合。PEG 与生物素的连接形成延长的间隔臂，确保生物素顺利进入蛋白质的结合位点，同时 PEG 部分显著提高了生物素-PEG 结合物的溶解度。

N-Boc-Biocytin 是一种含有羧基与 Boc 保护胺的生物素 PEG 连接子。其羧基可与一级氨基 (-NH2) 反应生成稳定且不可逆的酰胺键。Boc 基团在酸性条件下可被去保护，以释放出可用于进一步结合的游离胺。