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  • 抑制剂&激动剂
    10
    TargetMol | Inhibitors_Agonists
  • 重组蛋白
    21
    TargetMol | Recombinant_Protein
  • 多肽产品
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    TargetMol | Peptide_Products
  • 检测抗体
    29
    TargetMol | Antibody_Products
  • HSD17B13-IN-72
    T866633004661-16-6
    HSD17B13-IN-72 (Compound 62) 作为一种羟基类固醇17β-脱氢酶13 (HSD17B13) 抑制剂,展现出极高的效力,其对雌二醇的IC50值低于0.1 μM。该化合物主要应用于肝病和代谢性疾病的研究领域。
    • 待询
    10-14周
    规格
    数量
  • BIIB 722 Mesylate
    T83977261505-81-1In house
    BIIB 722 Mesylate 是一种选择性钠氢交换抑制剂,具有心脏保护作用,可用于研究心肌缺血和心肌梗死。
    • ¥ 1300
    现货
    规格
    数量
  • nbi-34041
    SB-723620, SB723620, SB 723620, NBI34041
    T33607268545-87-5
    NBI-34041 is an effective and high-affinity CRF1 receptor antagonist that effectively reduces endocrine responses to CRF(1) receptor-mediated pharmacological and behavioral challenges.
    • ¥ 15000
    8-10周
    规格
    数量
  • MB725
    MB-725, MB 725
    T332192230058-99-6
    MB725 is a strong and selective inducer of viability reduction in several cancer cell lines containing the oncogenic p53-Y220C mutation.
    • ¥ 21600
    10-14周
    规格
    数量
  • AB-729
    T402592634739-74-3
    AB-729, a nucleoside analogue functioning as an RNA interference (RNAi), links to a GalNAc (N-acetylgalactosamine) trimer ligand facilitating hepatocyte uptake through the asialoglycoprotein receptor (ASGR). This compound effectively impedes viral replication and diminishes HBV antigens.
    • ¥ 10600
    期货
    规格
    数量
  • DB722
    T64372433735-90-1
    DB722是一种具有DNA 结合活性的呋喃脒类似物。DB722显示抗增殖活性。
    • ¥ 1290
    现货
    规格
    数量
  • Cyclotraxin B acetate(1203586-72-4 free base)
    TP2068L
    Cyclotraxin B acetate(1203586-72-4 free base) 是 TrkB 受体的拮抗剂;抑制 BDNF 诱导的 TrkB 活性 (IC50 = 0.30 nM)。变构改变 TrkB 受体构象但不改变 BDNF 结合。防止 BDNF 引起的小鼠冷异常性疼痛。还显示在小鼠中表现出推定的抗焦虑特性。
    • ¥ 1680
    现货
    规格
    数量
  • Hodgkinsine B
    T38210586955-76-2
    Hodgkinsine B is an alkaloid and isomer of hodgkinsine that has analgesic activity.1It increases the latency to tail withdrawal in the tail-flick test in mice when administered at a dose of 10 mg kg. 1.Kodanko, J.J., Hiebert, S., Peterson, E.A., et al.Synthesis of all low-energy stereoisomers of the tris(pyrrolidinoindoline) alkaloid hodgkinsine and preliminary assessment of their antinociceptive activityJ. Org. Chem.72(21)7909-7914(2007)
    • ¥ 10214
    期货
    规格
    数量
  • Destruxin B2
    T3577179386-00-8
    Destruxin B2 is a cyclic hexadepsipeptide mycotoxin that has been found in M. anisopliae and has antiviral, insecticidal, and phytotoxic activities.1,2,3 It inhibits secretion of hepatitis B virus surface antigen (HBsAg) by Hep3B cells expressing hepatitis B virus (HBV) DNA (IC50 = 1.3 μM).1 Destruxin B2 is toxic to Sf9 insect cells in an electric cell-substrate impedance sensing (ECIS) test with a 50% inhibitory concentration (ECIS50) value of 92 μM.4 It is also phytotoxic to B. napus leaves.3 |1. Yeh, S.F., Pan, W., Ong, G.-T., et al. Study of structure-activity correlation in destruxins, a class of cyclodepsipeptides possessing suppressive effect on the generation of hepatitis B virus surface antigen in human hepatoma cells. Biochem. Biophys. Res. Commun. 229(1), 65-72 (1996).|2. Male, K.B., Tzeng, Y.-M., Montes, J., et al. Probing inhibitory effects of destruxins from Metarhizium anisopliae using insect cell based impedance spectroscopy: Inhibition vs chemical structure. Analyst 134(7), 1447-1452 (2009).|3. Buchwaldt, L., and Green, H. Phytotoxicity of destruxin B and its possible role in the pathogenesis of Alternaria brassicae. Plant Pathol. 41(1), 55-63 (1992).
    • ¥ 8608
    期货
    规格
    数量
  • TAN 420E
    T3639791700-93-5
    TAN 420E is a bacterial metabolite originally isolated from Streptomyces. It scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in a cell-free assay (IC50 = 1.3 μM) and reduces thiobarbituric acid reactive substances (TBARS) in rat liver microsomes by 72% when used at a concentration of 100 μg/ml. TAN 420E is active against B. brevis, B. cereus, M. flavus, and S. aureus (MICs = 50-100 μg/ml). It is cytotoxic to P388 and KB lymphocytic leukemia cells (EC50s = 0.022 and 0.3 μg/ml, respectively).
    • ¥ 3830
    35日内发货
    规格
    数量
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