apn

APN-C3-PEG4-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

APN-PEG4-BCN is a cleavable four-unit polyethylene glycol (PEG) linker, employed in the synthesis of antibody-drug conjugates (ADCs)[1].

APN-PEG4-tetrazine is a cleavable ADC linker compound comprised of four PEG units, specifically designed for the synthesis of antibody-drug conjugates (ADCs)[1].

APN-PEG5-VC-PAB-MMAE 为 INA03 中的药物-连接子偶联部分，后者为针对 CD71 的转铁蛋白竞争性抗体-药物偶联物。

APN-PEG4-Amine (hydrochloride) is a cleavable four-unit polyethylene glycol (PEG) linker utilized in the synthesis of antibody-drug conjugates (ADCs)[1].

APN-C3-NH-Boc is a alkyl ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

APN-C3-PEG4-alkyne is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

APN-PEG36-tetrazine是APN-PEG4-tetrazine的类似物，后者作为具有可降解(cleavable)特性的含四个单元PEG的ADC linker，应用于抗体偶联活性分子(ADC)的合成。

APN- NH2 is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

APN-PEG4-PFP is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

APN-PEG4-DBCO is a cleavable linker for antibody-drug conjugates (ADCs), comprised of a four-unit PEG and a DBCO moiety. It finds application in the synthesis of ADCs[1].

APN AKT-IN-1 is a potent dual inhibitor of aminopeptidase N (APN) and protein kinase B (AKT), exhibiting IC50 values of 0.21 μM and 0.27 μM for APN and AKT inhibition, respectively. This compound effectively suppresses the phosphorylation of glycogen synthase kinase 3 beta (GSK3β), which serves as an intracellular substrate of AKT [1].

Bestatin (Ubenimex) 是 CD13 (Aminopeptidase N) APN 和 leukotriene A4 hydrolase 抑制剂，可用于癌症研究。

Alunacedase alfa (APN-01) 是一种可溶性血管紧张素转化酶 2（hrsACE2），具有抗病毒活性，能够减少 SARS-CoV-2 与细胞膜结合 ACE2 的竞争性进入。Alunacedase alfa 可模拟体内的 ACE2可用于研究新型冠状病毒感染、肺性高血压和急性肺损伤。

CTSL CAPN1-IN-2 (Compound 14b) 是一种口服活性抑制剂，针对CTSL和CAPN1，其IC50值分别为6.88 nM和347.6 nM。该化合物展示了抗炎作用和良好的药代动力学属性。此外，CTSL CAPN1-IN-2 通过阻断病毒入侵，表现出对冠状病毒的广谱抗病毒活性。

Capnoidine is a potential new anti-inflammatory drug lead candidate for diseases where current standard-of-care often fails and is associated with major side effects.

O-Methylbulbocapnine 是一种天然产物，可用作天然产物对照品，用于生命科学相关领域的研究，其产品编号为 TN8655。

Zapnometinib (ATR-002) 是 CI-1040 的活性代谢物，是一种 MEK 抑制剂，IC50值为 5.7 nM，有抗流感病毒的抗病毒和抗菌活性。

Bmapn 作为一种合成卡西酮，显示了奖励和强化的性质。它能降低多巴胺转运蛋白的活性，并在纹状体中提升多巴胺受体 D2 的基因表达水平。

APNEA ((2R,3R,4S,5R)-2-[6-[2-(4-aminophenyl)ethylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol) 是腺苷 A3 受体的非选择性激动剂。

Capnolactone 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T124692，CAS号为 53771-63-4。

Bulbocapnine hydrochloride 是一种阿朴啡生物碱、多巴胺受体 (dopamine receptor) 抑制剂，抑制多巴胺合成，具抗精神病、抗惊厥和镇痛作用。

Chlamydia pneumoniae-IN-1 是一种对衣原体有抑制作用的苯并咪唑类化合物，在低浓度下即可对肺炎衣原体产生抑制作用。Chlamydia pneumoniae-IN-1 具有抗菌活性，对CV-6菌株的 MIC 为12.6 μM，可用于研究肺部感染。

4-Nitrobenzoic acid (4Nitrobenzoic acid) 是一种药物中间体，常在叶酸、DABA、PABA 和染料的生产中出现。