3
2
3
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T40115 |
GAD65 (206-220)
GAD65 (206-220) |
||
GAD65 (206-220) is a synthetic peptide derived from glutamic acid decarboxylase (GAD) 65, specifically corresponding to residues 180-188. It is known that GAD65 interacts with I-Ag7 MHC class II molecules and is a significant pancreatic antigen that self-reactive T cells target in type I diabetes mellitus. | |||
T82354 |
GAD65 (524-543)
|
||
GAD65 (524-543) 是具有生物活性的肽,属于谷氨酸脱羧酶 65 (GAD65) 氨基酸片段 524-543。作为胰岛抗原的关键片段之一,该肽在自发性自身免疫性糖尿病非肥胖糖尿病 (NOD) 小鼠模型中,可诱导增殖性 T 细胞反应。GAD65 (524-543) 对T细胞克隆BDC2.5具有特异性刺激作用,但可能存在亲和力较低的问题。此外,p524-543免疫可增强NOD小鼠对通过BDC2.5 T细胞过继转移诱导的1型糖尿病的敏感性。 | |||
T80218 |
GAD65(247-266) epitope TFA
|
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
GAD65(247-266) epitope TFA 为T细胞表位,与I-Ag7(I型糖尿病相关分子)竞争性结合,亲和力较低。该表位源自胰岛抗原,GAD65 是谷氨酸脱羧酶 65,涉及将谷氨酸转换为γ-氨基丁酸(GABA)。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3836 |
Eudesmin
|
MAPK; S6 Kinase | MAPK; PI3K/Akt/mTOR signaling |
Eudesmin 通过抑制S6K1信号通路来干扰成脂分化,具有抗肿瘤、抗炎和抗菌活性。 | |||
T2983 |
3,4,5-Trimethoxycinnamic acid
3-(3,4,5-Trimethoxyphenyl)acrylic Acid,O-Methylsinapic acid,3,4,5-三甲氧基肉桂酸 |
GABA Receptor; Endogenous Metabolite | Membrane transporter/Ion channel; Metabolism; Neuroscience |
3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) 是从远志中分离得到的苯丙素类天然产物,可延长动物的睡眠时间,增强 GAD65 和 GABAA 受体 γ 亚基,具有抗应激作用。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04699 |
GAD65 Protein, Human, Recombinant (GST)
glutamate decarboxylase 2 (pancreatic islets and brain, ... |
Human | Baculovirus Insect Cells |
GAD65 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 92.6 kDa and the accession number is Q05329. | |||
TMPY-01590 |
GAD65 Protein, Mouse, Recombinant (His & GST)
glutamate decarboxylase 2 (pancreatic islets and brain, ... |
Mouse | Baculovirus Insect Cells |
GAD65 Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 93 kDa and the accession number is P48320. | |||
TMPY-03515 |
GAD65 Protein, Mouse, Recombinant
glutamate decarboxylase 2 (pancreatic islets and brain, ... |
Mouse | Baculovirus Insect Cells |
GAD65 Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 65.4 kDa and the accession number is P48320. |