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抑制剂 & 化合物

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Cat. No. Product Name Target Signaling Pathways
T10663 Calcitriol-d6

Calcitriol D6,骨化三醇 D6

Others Others
Calcitriol D6 is the deuterated form of Calcitriol, which is the hormonally active form of vitamin D. Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor.
T19228 Calcitriol Impurities D

24-Homo Calcitriol,24-Homo-1,25-dihydroxyvitamin D3

Antiviral Immunology/Inflammation
Calcitriol Impurities D (24-Homo Calcitriol) 是维生素的一种激素形式,可促进HL-60人早幼粒细胞白血病细胞分化为单核细胞。Calcitriol Impurities D 具有骨吸收活性,抑制人类免疫缺陷病毒在人体细胞中的复制。Calcitriol Impurities D 具有抗病毒活性们可以用于治疗艾滋病和病毒感染。
T35524 (1S)-Calcitriol

(1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion[1]. 3‐epi‐Calcitroic acid is an end product of (1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3; 3‐epi‐1a,25(OH)2D3) metabolism by rat CYP24A1[1]. [1]. Steve Y Rhieu, et al. Metabolic stability of 3-epi-1α,25-dihydr...
T19226 Calcitriol Derivatives

Others Others
Calcitriol Derivatives is an analog of vitamin D3.
T19227 Calcitriol Impurities A

Others Others
Calcitriol Impurities A refers to the contaminants found in Calcitriol, the hormonally active metabolite of vitamin D3, which serves to activate the vitamin D receptor.
T11645 Impurity C of Calcitriol

Others Others
Impurity C of CalcitriolCalcitriol 的杂质。Impurity C of Calcitriol 可用于合成维生素D3。
T11643 Impurity B of Calcitriol

1β,25-Dihydroxyvitamin-D3,1-Epicalcitriol

Others Others
Impurity B of Calcitriol is an impurity of Calcitriol. Calcitriol is the hormonally active form of vitamin D, Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).
T15269 Falecalcitriol

Others Others
Falecalcitriol is an analog of calcitriol. It has a higher potency both in vivo and in vitro systems, which is longer duration of action in vivo.
T19869 Elocalcitol

Ro 26-9228,BXL 628

Elocalcitol is a calcitriol analog for inhibition of prostate cell growth.
T35536 Tpl2 Kinase Inhibitor (hydrochloride)

Tpl2 kinase inhibitor is an inhibitor of tumor progression locus 2 (Tpl2; IC50= 0.05 μM).1It is selective for Tpl2 over MEK, p38 MAPK, Src, MK2, and PKC (IC50s = >40, 180, >400, 110, and >400 μM, respectively). Tpl2 kinase inhibitor inhibits LPS-induced TNF-α production in isolated human monocytes and whole blood (IC50s = 0.7 and 8.5 μM, respectively). It enhances differentiation induced by calcitriol in HL-60 and U937 leukemia cells when used at a concentration of 5 μM.2Tpl2 kinase inhibitor (5...

化合物

Calcitriol-d6
Cat.No: T10663
Synonym: Calcitriol D6,骨化三醇 D6
Target: Others
Calcitriol Impurities D
Cat.No: T19228
Synonym: 24-Homo Calcitriol,24-Homo-1,25-dihydroxyvitamin D3
Target: Antiviral
(1S)-Calcitriol
Cat.No: T35524
Synonym:
Target:
Calcitriol Derivatives
Cat.No: T19226
Synonym:
Target: Others
Calcitriol Impurities A
Cat.No: T19227
Synonym:
Target: Others
Impurity C of Calcitriol
Cat.No: T11645
Synonym:
Target: Others
Impurity B of Calcitriol
Cat.No: T11643
Synonym: 1β,25-Dihydroxyvitamin-D3,1-Epicalcitriol
Target: Others
Falecalcitriol
Cat.No: T15269
Synonym:
Target: Others
Elocalcitol
Cat.No: T19869
Synonym: Ro 26-9228,BXL 628
Target:
Tpl2 Kinase Inhibitor (hydrochloride)
Cat.No: T35536
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T6316 Calcitriol

Topitriol,Rocaltrol,Calcijex,RO215535,骨化三醇,1,25-Dihydroxyvitamin D3

Endogenous Metabolite Metabolism
Calcitriol (1,25-Dihydroxyvitamin D3) 是一种维他命 D 的代谢物,一种维他命 D 受体 (VDR) 的激动剂 (IC50=0.4 nM)。Calcitriol 增加肠道对钙和磷的吸收,并与甲状旁腺激素一起增加了骨吸收。
TQ0216 Ercalcitriol

1α,25-Dihydroxy Vitamin D2

Others Others
Ercalcitriol (1α,25-Dihydroxy Vitamin D2) 是维生素 D2 的活性代谢物。 Ercalcitriol 作为维生素 D 的生理活化形式,通过调节正常细胞和转化细胞中的导管素抗菌肽 (CAMP) 和防御素 β-4 (DEFB4) 基因来增强免疫力,从而对抗病原体感染。

天然产物

Calcitriol
Cat.No: T6316
Synonym: Topitriol,Rocaltrol,Calcijex,RO215535,骨化三醇,1,25-Dihydroxyvitamin D3
Target: Endogenous Metabolite
Ercalcitriol
Cat.No: TQ0216
Synonym: 1α,25-Dihydroxy Vitamin D2
Target: Others
TargetMol Loading
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