首页工具

Renin Protein, Mouse, Recombinant (His)

产品编号 TMPY-01231

别名: Ren-A, Ren-1, Ren1, Ren1d, Ren, D19352, Rnr, Ren1c, renin, Rn-1

Renin-1, also known as Ren-1, Angiotensinogenase and Kidney renin, is a member of the peptidase A1 family. Renin-1 is synthesized by the juxtaglomerular cells of the kidney in response to decreased blood pressure and sodium concentration. androgen and thyroid hormones influence levels of Renin-1 in mouse submandibular gland (SMG) primarily by regulating the amount of Renin-1 mRNA available for translation. Renin-1 is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. It is expressed at relatively low levels in mouse SMG and kidney. Ren-2 is expressed at high levels in the mouse SMG and at very low levels, if at all, in the kidney. Ren-1 and Ren-2 are closely linked on mouse chromosome 1, show extensive homology in coding and noncoding regions and provide a model for studying the regulation of gene expression. 在相同实验条件下，摩尔浓度相同的化合物盐形式与游离态具有相同的生物活性，但盐形式 RN-1 dihydrochloride 的水溶性和稳定性通常比游离态更好。

TargetMol的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Renin Protein, Mouse, Recombinant (His) Chemical Structure

Renin Protein, Mouse, Recombinant (His), CAS N/A

规格	价格/CNY		货期	数量
50 μg	￥ 3,820		5日内发货

大包装超大折扣，点击咨询

Renin Protein, Mouse, Recombinant (His) 的其他形式现货产品:

Renin Protein, Human, Recombinant (His) RN-1 dihydrochloride

其他形式的 Renin Protein, Mouse, Recombinant (His):

Renin Protein, Human, Recombinant (His)
现货
RN-1 dihydrochloride
现货
Renin Protein, Human, Recombinant (R66K, His)
询价

更多批次查询请联系客服

生物活性

化学信息

存储 & 溶解度

参考文献

产品描述

别名	Ren-A, Ren-1, Ren1, Ren1d, Ren, D19352, Rnr, Ren1c, renin, Rn-1
分子量	43.2 kDa (predicted)

存储

Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month

计算器

摩尔浓度计算器

稀释计算器

配液计算器

分子量计算器

质量

浓度

容积

分子量

浓度 (起始)

容积 (起始)

浓度 (终)

容积 (终)

溶液体积

质量

配液浓度

参考文献

1. McKeon F.D.,et al.,(1986), Homologies in both primary and secondary structure between nuclear envelope and intermediate filament proteins. Nature 319:463-468. 2. Fisher D.Z.,et al., (1986), cDNA sequencing of nuclear lamins A and C reveals primary and secondary structural homology to intermediate filament proteins.Proc. Natl. Acad. Sci. U.S.A. 83:6450-6454. 3. Sylvius N.,et al.,(2005), In vivo and in vitro examination of the functional significances of novel lamin gene mutations in heart failure patients.J. Med. Genet. 42:639-647.

剂量换算

对于不同动物的给药剂量换算，您也可以参考 更多...

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL，一共给药动物10 只，您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。

母液配置方法：2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL)，如您需要配置的浓度超过该产品的溶解度，请先与我们联系。

体内配方的制备方法：取 50 μL DMSO 主液，加入 300 μL PEG300，混匀澄清，再加 50 μL Tween 80，混匀澄清，再加 600 μL ddH2O, 混匀澄清。

第一步：请输入动物实验的基本信息

剂量

mg/kg

每只动物体重

给药体积

μL

动物数量

第二步：请输入动物体内配方组成，不同的产品配方组成不同，如有配方需求，可先联系我们提供正确的体内配方。

% DMSO+

% +