tco-peg3-tco

TCO-PEG3-TCO is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

TCO-C3-PEG3-C3-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Amino-bis-PEG3-TCO is a three-unit cleavable polyethylene glycol (PEG) linker employed for the synthesis of antibody-drug conjugates (ADCs)[1].

DBCO-PEG3-TCO is a non-cleavable three-unit polyethylene glycol (PEG) linker employed for synthesizing antibody-drug conjugates (ADCs)[1].

Gly-Gly-Gly-PEG3-TCO is a cleavable three-unit polyethylene glycol (PEG) linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].

(S)-TCO-PEG3-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

TCO-PEG3-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

TCO-PEG3-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

TCO-PEG3-amide-C3-triethoxysilane is a polyethylene glycol (PEG)-based linker for proteolysis targeting chimeras (PROTACs) synthesis[1].

TCO-PEG3-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

TCO-PEG3-Biotin是一种PEG类的可降解(cleavable)ADC连接子，可用于合成抗体偶联药物 (ADC)，其TCO基团可以和含有Tetrazine基团的分子发生点击化学的iEDDA反应。

TCO-PEG3-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

TCO-PEG3-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

TCO-PEG3-oxyamine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

(S)-TCO-PEG3-acid是一种含末端羧酸 (COOH) 基团的点击化学PEG连接体。该末端羧酸能够与伯胺基团反应，生成稳定的酰胺键。(S)-TCO-PEG3-acid作为一种基于PEG的PROTAC连接体 (PROTAC linker)，适用于PROTAC的合成。

(S)-TCO-PEG8-acid 为一种带末端羧酸 (COOH) 基团的点击化学 PEG 连接体，该基团可与伯胺基团反应形成稳定的酰胺键。作为一种基于 PEG 的PROTAC连接体 (PROTAC linker)，(S)-TCO-PEG8-acid 用于合成PROTAC。相比 (S)-TCO-PEG3-acid，(S)-TCO-PEG8-acid 的长度更长。

TCO4-PEG3-Maleimide 是一种属于 PEG 类的 PROTAC linker。它包含 TCO 和 Maleimide 基团，能够分别与 tetrazine 基或硫氧基 (thiol group) 进行特异性的“click”反应或“巯基-丙烯酰胺”反应。

TCO4-PEG3-Maleimide 是一种 PEG 类的 PROTAC linker。它包含 TCO 和 Maleimide 基团，可以分别与 tetrazine 基或者硫氧基 (thiol group) 进行特异性的“click”反应或“巯基-丙烯酰胺”反应。

Ald-Ph-PEG4-bis-PEG3-methyltetrazine 是一种配有 Tetrazine 基团的点击化学试剂，可进行逆电子需求 Diels-Alder 反应 (iEDDA) 与含 TCO 基团的分子结合。此化合物同时也作为一种含7个单元的 PEG 的可降解 (cleavable) ADC linker，用于抗体偶联活性分子 (ADC) 的合成。

TCO-PEG3-CH2-aldehyde 是一种用于合成抗体偶联活性分子 (ADC) 的可降解 (cleavable) 三单元 PEG ADC linker。作为点击化学试剂，其含有 TCO 基团，可与含 Tetrazine 基团的分子进行逆电子需求 Diels-Alder 反应 (iEDDA)。

Amino-PEG4-bis-PEG3-methyltetrazine 为含 7 个单元 PEG 的可降解ADC linker，专用于ADC的合成。此化合物也是一种点击化学试剂，具备 Tetrazine 基团，能够与含 TCO 基团的分子进行逆电子需求 Diels-Alder 反应 (iEDDA)。

Mal-PEG4-(PEG3-DBCO)-(PEG3-TCO) 是一种含有10个PEG单元的可降解ADC linker，适用于抗体偶联活性分子(ADC)的合成。作为一种点击化学试剂，其结构中包含TCO基团，能够与带有Tetrazine基团的分子进行逆电子需求Diels-Alder反应(iEDDA)。

Me-Tet-PEG3-NHBoc, an ADC linker featuring three PEG units, leverages its Tetrazine group to engage in a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds containing TCO groups.

(S)-TCO-PEG3-NH2, an ADC linker featuring three PEG units, utilizes its TCO group to facilitate the inverse electron demand Diels-Alder reaction (iEDDA) with tetrazine-group molecules.