TCO-PEG3-TCO is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
TCO-C3-PEG3-C3-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
(S)-TCO-PEG3-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
TCO-PEG3-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
TCO-PEG3-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
TCO-PEG3-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
TCO-PEG3-Biotin is a cleavable ADC linker comprised of three PEG units. It is primarily employed in the synthesis of ADCs, which are antibody-drug conjugates [1].
TCO-PEG3-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
TCO-PEG3-oxyamine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Me-Tet-PEG3-NHBoc, an ADC linker featuring three PEG units, leverages its Tetrazine group to engage in a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds containing TCO groups.
(S)-TCO-PEG3-NH2, an ADC linker featuring three PEG units, utilizes its TCO group to facilitate the inverse electron demand Diels-Alder reaction (iEDDA) with tetrazine-group molecules.
Me-Tet-PEG3-NH2, an ADC linker comprising three PEG units, utilizes its Tetrazine group to initiate an inverse electron demand Diels-Alder reaction (iEDDA) with compounds possessing TCO groups. This specific functionality allows for targeted chemical bonding essential in bioconjugation applications.
Me-Tet-PEG3-Maleimide, an ADC Linker comprising three PEG units, incorporates a Tetrazine group capable of performing a specific inverse electron demand Diels-Alder reaction (iEDDA) with TCO group-containing compounds. Additionally, its maleimide group (-Maleimide) is prone to degradation in aqueous media and has applications in drug delivery studies.
Biotin-PEG3-Me-Tet, an ADC linker consisting of three PEG units, utilizes its Tetrazine group to participate in a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds containing TCO groups.