staining

Cetyldimethylethylammonium Bromide 可用于诱导细胞外分泌 β-半乳糖苷酶。

Berberine (Umbellatine) 属于生物碱类天然产物，可以激活 AMPK、抑制 DNA 拓扑异构酶、诱导 ROS 生成。Berberine 具有抗肿瘤、抗菌、降血糖、降血脂等生物学活性。

5-Bromo-4-chloro-3-indolyl β-D-glucopyranoside (X-Glc) 是β-半乳糖苷酶(β-galactosidase)的显色底物，在β-半乳糖苷酶的催化下会产生蓝色产物。5-Bromo-4-chloro-3-indolyl β-D-glucopyranoside 常用于β-半乳糖苷酶的原位染色检测以及蓝白斑筛选。

Chromomycin A3（色霉素 A3）一种由链霉菌产生的抗生素，在二价阳离子存在的情况下与富含gc的DNA序列结合，抑制DNA复制和转录；也被用作荧光DNA染色剂和检测剂；对霍奇金氏病、肺腺癌、黑色素瘤、乳腺癌等疾病具有抗癌活性。

AA-dUTP [sodium salt] is a fluorescent dye used for staining cDNA.

Phalloidin 是一种在鹅膏菌中发现的双环七肽，参与 F-肌动蛋白染色。 Phalloidin 是一种肌动蛋白不可逆聚合成微丝的化合物。Phalloidin 可干扰细胞的运动和生长，可用于标记脑血管。

Octyl Orlistat, 作为一种潜在的脂肪酸合成酶(FASN)抑制剂, 在减少肿瘤细胞增殖方面显示出显著成效。通过靶向FASN并引发细胞凋亡，Orlistat 正被研究用作抗肿瘤化合物。与Cerulenin和C75相比，Orlistat在细胞培养和细胞系中表现出更高的抑制效力。在LN229细胞中，使用200 µM Orlistat处理48小时后，细胞生长减少了63.9 ± 8.7%，而在LT68细胞中细胞生长的减少率为76.3 ± 23.7%。经Orlistat处理的器官型切片培养显示，在Ki67染色后增殖减少，并观察到caspase-3的增加剪切。

Setocyanine can be used in the staining DNA.

RAD16-I hydrochloride is a self-assembling peptide with nanofibrous morphology that provides an optimal microenvironment for the proliferation and differentiation of human mesenchymal stem cells (hMSC) into chondrocytes. This peptide, known as RAD16-I, has been extensively studied and serves as a model to assess the amyloid-like staining properties of self-assembling peptide nanofibers (SAPNFs).

Insulin β Chain Peptide (15-23), also referred to as INS, is an insulin-derived peptide that is specifically recognized by islet-associated T cells. The tetramer of Insulin β Chain Peptide (15-23) effectively stained the INS-reactive CTL clone G9C8; however, neither this tetramer nor the negative control tetramer (TUM) exhibited staining on the splenic CD8+ T cells obtained from NOD or 8.3-TCRαβ transgenic NOD mice.

DL-Leucyl-DL-phenylalanine, a dipeptide, serves as a substrate for detecting two distinct regions of dipeptidase staining on gels in both Drosophila simulans and Drosophila melanogaster.

AG-012986 is a multitargeted cyclin-dependent kinase (CDK) inhibitor active against CDK1, CDK2, CDK4 6, CDK5, and CDK9, with selectivity over a diverse panel of non-CDK kinases. AG-012986 showed antiproliferative activities in vitro with IC(50)s of <100 nmol L in 14 of 18 tumor cell lines. In vivo, significant antitumor efficacy induced by AG-012986 was seen (tumor growth inhibition, >83.1%) in 10 of 11 human xenograft tumor models. AG-012986 also showed dose-dependent retinoblastoma Ser(795) hypophosphorylation, cell cycle arrest, decreased Ki-67 tumor staining, and apoptosis in conjunction with antitumor activity.

AG-012986 HCl is a multitargeted cyclin-dependent kinase (CDK) inhibitor active against CDK1, CDK2, CDK4 6, CDK5, and CDK9, with selectivity over a diverse panel of non-CDK kinases. AG-012986 HCl showed antiproliferative activities in vitro with IC(50)s of <100 nmol L in 14 of 18 tumor cell lines. In vivo, significant antitumor efficacy induced by AG-012986 HCl was seen (tumor growth inhibition, >83.1%) in 10 of 11 human xenograft tumor models. AG-012986 HCl also showed dose-dependent retinoblastoma Ser(795) hypophosphorylation, cell cycle arrest, decreased Ki-67 tumor staining, and apoptosis in conjunction with antitumor activity.

AZ-Tak1 is a potent and a relatively selective inhibitor of TAK1 kinase activity, with an IC50 of 0.009 mM. AZ-Tak1 treatment decreased the level of p38 and ERK in mantle cell lymphoma cells, and induced apoptosis in a dose and time dependent manner, with an IC50 of 0.1–0.5 mM. Using the annexin-V and PI staining and FACS analysis, After 48 hours of incubation, AZ-Tak1 (0.1 mM) induced apoptosis in 28%, 34% and 86% of Mino, SP53, and Jeko cells, respectively, which was increased to 32%, 42%, and 86% when 0.5 mM concentration was used.

MHY219 is a novel HDAC inhibitor. MHY219 induces apoptosis via up-regulation of androgen receptor expression in human prostate cancer cells. MHY219 was shown to enhance the cytotoxicity on DU145 cells (IC50, 0.36 μM) when compared with LNCaP (IC50, 0.97 μM) and PC3 cells (IC50, 5.12 μM). MHY219 showed a potent inhibition of total HDAC activity when compared with SAHA. MHY219 increased histone H3 hyperacetylation and reduced the expression of class I HDACs (1, 2 and 3) in prostate cancer cells. MHY219 effectively increased the sub-G1 fraction of cells through p21 and p27 dependent pathways in DU145 cells. MHY219 significantly induced a G2 M phase arrest in DU145 and PC3 cells and arrested the cell cycle at G0 G1 phase in LNCaP cells. Furthermore, MHY219 effectively increased apoptosis in DU145 and LNCaP cells, but not PC3 cells, according to Annexin V PI staining and Western blot analysis. These results indicate that MHY219 is a potent HDAC inhibitor that targets regulating mu......

CDKI-83 is a potent CDK9 inhibitor. The compound shows effective anti-proliferative activity in human tumour cell lines with GI50 <1 μM, and is capable of inducing apoptosis in A2780 human ovarian cancer cells as determined by the activated caspase-3, Annexin V PI double staining and accumulated cells at the sub-G1 phase of cellcycle. The research results suggest that combined inhibition of CDK9 and CDK1 may result in the effective induction of apoptosis and CDKI-83 has the potential to be developed as an anti-cancer agent.

3,3-Diaminobenzidine tetrahydrochloride dehydrate 作为染料，在组织化学（HC）及免疫组织化学（IHC）中应用广泛。该化合物主要用于过氧化物酶体染色和线粒体细胞色素c氧化酶活性的检测。

CELT-327是一种高效且选择性的荧光hA2B/A3腺苷受体拮抗剂，其Kivalues在A2B和A3受体上分别为35.6 nM和45.7 nM。在表达A2B腺苷受体的HCT116细胞中，CELT-327表现出剂量依赖性的膜荧光标记，荧光信号快速扩散并在细胞单层中均匀分布。在活的HCT116紧凑球体中，CELT-327展现出整个球体直径上的均匀染色，可达到球体深层区域。CELT-327可作为荧光腺苷受体探针用于荧光结合分析、活细胞成像、流式细胞术和荧光偏振分析。它是GPCR放射标记配体的合适替代品。激发和发射最大值（λ）分别为589 nm和616 nm。这些波长与作为TR-FRET分析中接受体染料使用兼容，与CoraFluor1 TR-FRET供体一同使用。

Xylene Cyanol FF 是三苯甲烷系列的酸性染料。该化合物在组织化学中用于血红蛋白过氧化物酶的染色，并可作为电泳DNA测序的示踪染料。在过氧化氢和高碘酸钾的存在下，Xylene Cyanol FF 的氧化反应会在Fe和Al的催化下加速。此性质使其能通过分光光度法测定溶液中的Fe和Al含量。

Sodium tungstate dihydrate, 99% (Sodium wolframate dihydrate, 99%) 作为电镜核酸和部分糖蛋白的染色剂，亦可用作蛋白质沉淀剂。

Potassium alum (Aluminum potassium sulfate dodecahydrate)，是一种卵清蛋白佐剂，可用于诱发小鼠过敏反应，用于细胞培养，并且适用于细菌染色。

Azure II 是用于核染色的染料。

DSPE-PEG-FITC, MW 2000，是一种结合了荧光素的聚乙二醇脂质，用于制备脂质体以作为靶向药物递送的载体。FITC作为绿色染料，具有在494 nm的峰值吸收和在520 nm的最大发射，可用于生物样品或纳米颗粒的染色。

DSPE-PEG-FITC, MW 3400是一种与荧光素偶联的PEG脂质，用于制备作为靶向给药载体的脂质体。FITC是一种绿色荧光染料，具有494 nm的峰值吸收和520 nm的最大发射，适用于生物样品或纳米颗粒的染色。