ophiobolin a

Ophiobolin A is a fungal metabolite and a phytotoxin and is an effective and irreversibly inhibitor of calmodulin-activated cyclic nucleotide phosphodiesterase (IC50: 9 μM). Ophiobolin A also has antimicrobial and anticancer activity.

Ophiobolin G 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T123965，CAS号为 90108-63-7。

Ophiobolin H 是一种真菌代谢产物，能够从Aspergillus ustus中提取。Ophiobolin H 可抑制枯草芽孢杆菌培养物的生长，并且在剂量高达 375 mg kg 时会导致日龄雏鸡的听觉过敏。

inhibitor of human CCR5 binding to HIV-1 gp120

Anhydroophiobolin A is an ophiobolin fungal metabolite that has been found in C. heterostrophus fermentation broths. It is cytotoxic to HepG2 and K562 cancer cells (IC50s = 55.7 and 39.5 μM, respectively).

Anhydroepiophiobolin A is a sesterterpenoid fungal metabolite that has been found in B. oryzae. It is cytotoxic to HepG2 and K562 cells (IC50s = 47.1 and 35.6 μM, respectively) as well as A549, SKOV3, SK-MEL-2, XF498, and HCT15 cells (IC50s = 1.6-1.9 μg/ml). Anhydroepiophiobolin A is phytotoxic to S. viridis and D. erucoides in a leaf puncture assay.

Ophiobolin B is a sesterterpene Helminthosporium oryzae metabolite, inhibits proton extrusion from maize coleoptiles.