dbco-biotin

DBCO-Biotin (Azadibenzocyclooctyne-Biotin conjugate) 是一种基于烷基链的 PROTAC linker。

DBCO-S-S-PEG3-biotin 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。

DBCO-Sulfo-Link-biotin is a cleavable linker employed in the synthesis of antibody-drug conjugates (ADCs) [1].

Dde Biotin-PEG4-DBCO is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

DBCO-NHCO-PEG12-biotin is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

DBCO-NHCO-PEG2-Biotin is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

DBCO-NHCO-PEG6-Biotin is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

DBCO-SS-PEG4-Biotin is a cleavable link mid-functional ADC linker composed of a 4-unit PEG moiety. It finds utility in the synthesis of antibody-drug conjugates (ADCs)[1].

Diazo Biotin-PEG3-DBCO is a cleavable three-unit polyethylene glycol (PEG) linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].

N-(DBCO-PEG4)-N-Biotin-PEG4-NHS is a PEG-based PROTAC linker suitable for synthesizing PROTACs[1].

PC DBCO-PEG3-biotin is a trimeric polyethylene glycol (PEG) linker, specifically designed for antibody-drug conjugate (ADC) synthesis, with a cleavable moiety consisting of a dibenzocyclooctyne (DBCO) group and a biotin molecule. This linker provides a platform for the efficient attachment of drugs to antibodies, facilitating the targeted delivery and controlled release of therapeutic agents in ADCs[1].

WSPC Biotin-PEG3-DBCO is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Biotin-PEG-azide (MW 600) 是一种以 PEG 为基础的 PROTAC linker，用于合成 PROTAC。其包含的 Azide 基团能够与具有 Alkyne 基团的分子进行铜催化的叠氮-炔环加成反应（CuAAc）。此外，该化合物还可与含 DBCO 或 BCN 基团的分子发生环张力促进的炔-叠氮环加成反应 (SPAAC)。

Biotin-PEG-azide (MW 5000) 是一种基于PEG结构的PROTAC linker，适用于PROTAC合成。该化合物含有Azide基团，能够与含有Alkyne基团的分子通过铜催化的叠氮-炔环加成反应（CuAAc) 结合。此外，它也可以与含有DBCO或BCN基团的分子进行环张力促进的炔-叠氮环加成反应 (SPAAC)。