5-HT Receptor

5-hydroxytryptamine receptors or 5-HT receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in the central and peripheral nervous systems. They mediate both excitatory and inhibitory neurotransmission.

Cat. No.	Product Name	CAS No.	Purity
T10498	5-HT2A antagonist 1 化合物 T10498	204643-75-4	98%
T10498	5-HT2A antagonist 1 is a 5-HT2A antagonist. It may be useful in the treatment of gastrointestinal disorders circulatory disorders.
TQ0315	Tandospirone 坦度螺酮	87760-53-0	98%
TQ0315	Tandospirone (SM-3997) is a selective partial agonist of 5-HT1A receptor (Ki: 27 nM) that displays selectivity over SR-2, SR-1C, α1, α2, D1 and D2 receptors (Kis...
T12262	NPS ALX Compound 4a 化合物 T12262	299433-10-6	98%
T12262	NPS ALX Compound 4a is a potent and selective antagonist of 5-HT6 receptor (IC50 of 7.2 nM)
T4375	Methiothepin maleate 甲替平	19728-88-2	98%
T4375	Methiothepin maleate (Metitepine) 是一种 5-HT1、5-HT6、5-HT7 血清素受体拮抗剂，可阻断血清素自身受体。
T10075L2	2-Methyl-5-HT hydrochloride 化合物 T10075L2	845861-49-6	98%
T10075L2	2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.
T12842	SB-269970 化合物 T12842	201038-74-6	98%
T12842	SB-269970 is a antagonist of 5-HT7 receptor(pKi of 8.3).
TN4092	Galanolactone 化合物 TN4092	115753-79-2	98%
TN4092	Galanolactone has anti-5-HT effect, a diterpenoid isolated from ginger, is related to antagonism of 5-HT3 receptors, it has inhibit nitric oxide production with ...
T11302	Flumexadol 化合物 T11302	30914-89-7	98%
T11302	Flumexadol is a selective and affinity 5-HT2C receptor agonist with a Ki of 25 nM for the (+)-enantiomer of Flumexadol, and is 40-fold selective over the 5-HT2A ...
T12865	SCH-23390 maleate 化合物SCH-23390 maleate	87134-87-0	98%
T12865	SCH-23390 maleate (R-(+)-SCH-23390 maleate) 是多巴胺D1样受体选择性拮抗剂，与D1和D5受体结合的Ki 分别为 0.2 nM 和 0.3 nM。它也是人5-HT2C 受体激动剂，Ki 为 9.3 nM。它与5-HT2和5-HT1C 受体具有高亲和力。它还抑制 G 蛋白偶联的内向...
TN3235	7-Hydroxycadalene 化合物 TN3235	2102-75-2	98%
TN3235	7-Hydroxycadalene shows cytotoxicity activity against HCT-15 cell line with IC50 18.89 ± 1.2 uM.
T11293	(±)-Fabesetron hydrochloride 化合物 T11293	129299-81-6	98%
T11293	FK1052 hydrochloride is a potent 5-HT3 and 5-HT4 receptor dual antagonist.
T10075L	2-Methyl-5-HT maleate 化合物 T10075L	78263-91-9	98%
T10075L	2-Methyl-5-HT maleate (2-Methyl-5-hydroxytryptamine maleate) is a potent and selective 5-HT3 receptor agonist, which is shown to display anti-depressive-like eff...
T10371	Arotinolol 阿罗洛尔	68377-92-4	98%
T10371	Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker. Arotinolol also shows potency for inhibiting the binding of the radiol...
T22296	Cisapride hydrate 西沙比利	260779-88-2	98%
T22296	Cisapride acts directly as a selective agonist of serotonin 5-HT4 receptor with IC50 value of 0.483 μM. And It also acts indirectly as a parasympathomimetic.
T12899L	SEP-363856 hydrochloride 化合物SEP-363856 hydrochloride	1310422-41-3	99.99%
T12899L	SEP-363856 hydrochloride (SEP-856 hydrochloride) 是一种口服活性和 CNS 活性的精神药物，具有独特的非 D2/5-HT2A 作用机制，发挥其抗精神病样作用，具有治疗精神分裂症的潜力。
T24885L	Tiaspirone hydrochloride 噻螺酮盐酸盐	87691-92-7	99.98%
T24885L	Tiaspirone hydrochloride (BMY-13859 hydrochloride) 具有抗精神病活性。 Tiaspirone hydrochloride 影响大鼠大脑黑质致密带（A9 DA 细胞）和腹侧被盖区（A10 DA 细胞）多巴胺能神经元的电生理活性。
T1619	Trazodone hydrochloride 盐酸曲唑酮	25332-39-2	99.98%
T1619	Trazodone hydrochloride (Trazodone HCl) 是5 羟色胺受体拮抗剂和重吸收抑制剂，用作抗抑郁药，可治疗失眠和焦虑。
T21629	Loxapine 洛沙平	1977-10-2	99.98%
T21629	Loxapine 是 D2DR 和 D4DR 抑制剂和5-羟色胺能受体拮抗剂，是一种抗精神病药物，主要用于治疗精神分裂症。
T1509	Cyclobenzaprine hydrochloride 盐酸环苯扎林	6202-23-9	99.98%
T1509	Cyclobenzaprine hydrochloride (MK130 hydrochloride) 是一种具有抗抑郁活性的中枢作用肌肉松弛剂，可减少肌肉痉挛。
T0204	Protriptyline hydrochloride 盐酸普罗替林	1225-55-4	99.98%
T0204	Protriptyline hydrochloride (Protriptyline HCl) 是一种含有一个仲胺的三环结构抗抑郁试剂，可以用于抑郁和 ADHD 的相关研究。它使动物精力充沛起激励作用，并且有时用于嗜睡症的相关研究。