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Search Results for " insecticidal "

42

抑制剂 & 化合物

55

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T67914	Insecticidal agent 364	mTOR; Autophagy	Autophagy; PI3K/Akt/mTOR signaling
	Insecticidal agent 364是一种雷帕霉素激酶靶蛋白的选择性小分子抑制剂。Insecticidal agent 364具有抗肿瘤活性，通过抑制mTOR, Insecticidal agent 364旨在破坏参与癌细胞生长和存活的信号通路，从而潜在地抑制肿瘤生长。
T82064	Insecticidal agent 6	Parasite	Microbiology/Virology
	Insecticidal agent 6（化合物 Im）是昆虫兰尼碱受体（RyRs）的抑制剂，该化合物对 S. frugiperda RyRs 具有强效的抑制作用，其 EC50 值为0.6308 µM。该化合物在鳞翅目害虫中展现出卓越的杀虫效果，适用于病虫害研究。
T82065	Insecticidal agent 3
	Insecticidal agent 3 是一种昆虫生长调节剂 (IGRs)，特别针对 OfChtI, OfChtII 和 OfChi-h 的多几丁质酶抑制剂，Ki 值分别为 0.8 μM，11.9 μM 和 2.3 μM。该化合物通过扰乱正常生长和蜕皮过程，对两种鳞翅目害虫具有显著的杀虫活性。
T82066	Insecticidal agent 1
	Insecticidal agent 1 展示出比叶绿酮和川楝素更高的杀虫效力。
T79122	Insecticidal agent 2	Parasite	Microbiology/Virology
	Insecticidal agent 2 (example 2)为一种杀虫剂，展现对害虫的强效生长延迟效能。
T79762	Insecticidal agent 4
	4 (IA-8) 是一款针对分枝杆菌具有显著杀虫效果的芳基异恶唑啉衍生物。
T38845	Dodecamethylpentasiloxane	Parasite	Microbiology/Virology
	Dodecamethylpentasiloxane 可用作臭虫杀虫剂。 Dodecamethylpentasiloxane 是硅氧烷的一种成分，可用作硅油。
T0776	Phenothiazine ENT 38,吩噻嗪	Dopamine Receptor; Antibacterial; Antibiotic; Antifungal	GPCR/G Protein; Microbiology/Virology; Neuroscience
	Phenothiazine (ENT 38) 是一种抗生素，具有杀虫，抗菌，驱虫和杀真菌活性。它也可研究神经系统疾病。
T5836	Eprinomectin 依普菌素,MK-397	Parasite	Microbiology/Virology
	Eprinomectin (MK-397) 是一种阿维菌素，具有驱虫，杀虫杀螨活性。
T13683	Epsilon-momfluorothrin Momfluorothrin, (Z,1R,3R)-	Others	Others
	Epsilon-momfluorothrin (Momfluorothrin, (Z,1R,3R)-), a type I synthetic pyrethroid insecticide, exerts its insecticidal properties and triggers activation of the constitutive androstane receptor (CAR). Notably, its administration in rats has been observed to induce the development of hepatocellular tumors.
T12987	Spirodiclofen BAJ-2740,螺螨酯	Parasite	Microbiology/Virology
	Spirodiclofen (BAJ-2740) 是选择性非系统性的杀螨剂，来自新的化学类特酮酸衍生物，与目前市面上的杀螨剂无交叉耐药, 具有额外的杀虫性能。
T21686	CD 1530 CD-1530,CD1530	Retinoid Receptor	Metabolism
	CD 1530 是一种具有选择性和有效性的 RARγ激动剂(Kd:150 nM)，具有潜在的抗癌活性，对秀丽隐杆线虫显示出杀虫活性，可用于研究口腔癌变。
T19829	Chlorfenapyr Pylon,AC 303630,Pirate,AC-303630,AC303630,虫螨腈	Others	Others
	Chlorfenapyr (AC 303630) 是吡咯杀虫剂。在体内混合功能氧化酶的作用下，它可代谢为 CL 303268。它对多种昆虫具有活性，包括对拟除虫菊酯和有机磷酸盐杀虫剂敏感和具有抗性的昆虫。含 Chlorfenapyr (AC 303630) 的制剂已被用于控制白蚁，在农业中已被用于控制各种昆虫。
T63059	CRK12-IN-1	Antibiotic	Microbiology/Virology
	CRK12-IN-1 是一种有效的CRK12抑制剂。CRK12-IN-1具有杀虫活性，对布氏锥虫 (T.b. brucei) 和刚果锥虫 (T. congolense) 具有抑制作用EC50分别为1.3和18 nM。CRK12-IN-1能迅速杀死病原细胞。
T30965	Clavamine Clavamin
	Clavamine is an insecticidal.
T20507	Chlorthal NSC 12443,NSC-12443,NSC12443
	Chloroform has an insecticidal effect.
T37673	Asperlactone
	Asperlactone is a nematicidal, insecticidal, antibacterial, and antifungal polyketide metabolite produced from A. westerdijkiae.
T20651	Fenazaflor NSC 191025,NSC-191025,NC5016,NC 5016,Lovozal,NC-5016
	Finazaflo has insecticidal and acaricidal effects.
T20658	Etofenprox
	Etofenprox, a synthetic pyrethroid, has insecticidal efficacy against mosquito larvae & on non-target organisms.
T20195	Cartap hydrochloride Caldan,Cartap HCl,Cartap monohydrochloride,Dihydronereistoxin dicarbamate
	Cartap hydrochloride is an insecticidal derivative. It is used to control chewing and sucking insects on many crops.
T62069	Chitinase-IN-4
	Chitinase-IN-4 (compound 8f) 是一种有效的、选择性的 OfChi-h 抑制剂，其 IC50 值为 0.1 μM，具有良好的杀虫作用。
T38053	Aureothin
	Aureothin is a natural nitroaryl-substituted polyketide that exhibits antitumor, antifungal, and insecticidal activities. It is a non-competitive inhibitor of NADH:ubiquinone oxidoreductase of bovine heart, N. crassa, and E. coli (IC50s = 0.07, 0.08, and 22 nmol/mg protein, respectively).
T39255	β-Cyfluthrin beta-Cyfluthrin,β-Cyfluthrin
	β-Cyfluthrin is a type II synthetic pyrethroid compound commonly utilized as an active ingredient in agricultural insecticide products. It exerts its insecticidal properties by acting as a neurotoxicant, primarily impacting the calcium concentration within nervous tissue. This effect is achieved through the inhibition of Ca 2+ ATPase, a crucial component involved in calcium transport.
T25416	Fenvalerate Evercide 2362
	Fenvalerate is used as an insecticide. It is a mixture of four optical isomers which have different insecticidal activities. The 2-S alpha (or SS) configuration, known as esfenvalerate, is the most insecticidally active isomer. There is about 23% this iso
T74113	Sesquicillin A
	Sesquicillin A 是一种杀虫抗生素，从白纹虫中分离出来的真菌代谢物。Sesquicillin A 抑制A. salina 盐水虾的生长的 MIC 为6.25 µg/mL。
T32849	Loline
	Loline is a natural insecticidal and deterrent to a broad range of insects, including species in the Hemiptera, Coleoptera, Hymenoptera, Lepidoptera, and Blattodea orders. Loline deters species such as the bird cherry-oat aphid (genus Rhopalosiphum), larg
T82356	GABA-IN-1
	GABA-IN-1 (Compound 6)为GABA抑制剂，具备显著的杀幼虫效能与杀虫功能，在浓度为50 mg/L时，致死率达93%。
T82355	GABA-IN-2
	GABA-IN-2 (Compound 5) 为GABA抑制剂，展现出杀幼虫效果和显著的杀虫能力，在浓度50 mg/L下的死亡率达到87%。
T62122	Chitinase-IN-5
	Chitinase-IN-5 (8i) 是一种几丁质酶OfChi-h 的有效抑制剂 (IC50: 0.051 μM)，具有良好的杀虫作用。Chitinase-IN-5 能够用于研究绿色害虫防治和管理。
T81620	OfChi-h-IN-1
	OfChi-h-IN-1，一种高效的OfChi-h抑制剂，Ki为0.33 μM。该化合物能显著抑制幼虫生长发育，并表现出比Hexaflumuron更强的杀虫活性，是昆虫生长调节剂的新型候选物。
T83068	Antifungal agent 77
	Antifungalagent 77 (Compound 13h) 作为一种化合物，展现出对粘虫、棉铃虫、玉米螟及草地贪夜蛾的杀虫效力，其浓度为500 μg/mL时，相应的死亡率为30%、25%、40% 和 25%。同时，该化合物对斑马鱼胚胎具有毒性，其半致死浓度（LC50）为2.43 μg/mL。
T35909	Penicinoline
	Penicinoline is an alkaloid that has been found in Penicillium and has antimalarial, insecticidal, and anticancer activities.1,2 It is active against chloroquine-sensitive and -resistant strains of P. falciparum (IC50 = 25 μM for both).1 Penicinoline (1,000 ppm) is also active against the aphid A. gossypii.2 It inhibits proliferation of 95-D and HepG2 cancer cells (IC50s = 0.57 and 6.5 μg/ml, respectively) but not HeLa, KB, KBv200, or Hep-2 cells (IC50s = >100 μg/ml). \|1. Naveen, B., Ommi, N.B.,...
T75301	(R)-Dinotefuran
	(R)-Dinotefuran ((R)-MTI-446) 是一种新烟碱类农药，与消旋混合物相比，通过抑制烟碱乙酰胆碱受体 (nAChR) 对典型的吸吮性害虫Aphis gossypii 和Apolygus lucorum 表现出相当的杀虫活性 (1.7-2.4 倍)。(R)-Dinotefuran 具有良好的防治目标害虫的作用，同时减少对蜜蜂的危害。
T35771	Destruxin B2
	Destruxin B2 is a cyclic hexadepsipeptide mycotoxin that has been found in M. anisopliae and has antiviral, insecticidal, and phytotoxic activities.1,2,3 It inhibits secretion of hepatitis B virus surface antigen (HBsAg) by Hep3B cells expressing hepatitis B virus (HBV) DNA (IC50 = 1.3 μM).1 Destruxin B2 is toxic to Sf9 insect cells in an electric cell-substrate impedance sensing (ECIS) test with a 50% inhibitory concentration (ECIS50) value of 92 μM.4 It is also phytotoxic to B. napus leaves.3 ...
T75595	Loxosceles Bergeri Venom
	Loxosceles Bergeri Venom 是一种可以从Loxosceles Bergeri 中获得的毒液。Loxosceles 蜘蛛的毒液是一种复杂的毒素混合物，富含蛋白质、糖蛋白和低分子质量多肽。目前已鉴定出几种蛋白类，包括类虾蛋白酶金属蛋白酶、低分子杀虫肽、抑制剂半胱氨酸结肽 (ICK) 和磷脂酶 D。其中独特的酶，鞘磷脂酶 D 负责坏死的发展。
T75596	Loxosceles Pilosa Venom
	Loxosceles Pilosa Venom 是一种可以从Loxosceles Pilosa 中获得的毒液。Loxosceles 蜘蛛的毒液是一种复杂的毒素混合物，富含蛋白质、糖蛋白和低分子质量多肽。目前已鉴定出几种蛋白类，包括类虾蛋白酶金属蛋白酶、低分子杀虫肽、抑制剂半胱氨酸结肽 (ICK) 和磷脂酶 D。其中独特的酶，鞘磷脂酶 D 负责坏死的发展。
T75597	Loxosceles Spiniceps Venom
	Loxosceles Spiniceps Venom 是一种可以从Loxosceles Spiniceps 中获得的毒液。Loxosceles 蜘蛛的毒液是一种复杂的毒素混合物，富含蛋白质、糖蛋白和低分子质量多肽。目前已鉴定出几种蛋白类，包括类虾蛋白酶金属蛋白酶、低分子杀虫肽、抑制剂半胱氨酸结肽 (ICK) 和磷脂酶 D。其中独特的酶，鞘磷脂酶 D 负责坏死的发展。
T82357	GABA receptor Antagonist 1	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	GABA receptorAntagonist 1 (compound 7w) 在抑制PxRDL1GABAR方面具有高特异性，IC50为7.08 nmol/L。针对P. xylostella、S. frugiperda、S. exigua和S. litura的杀虫活性显著，相应的LC50值分别为0.09、0.84、0.87和0.68 mg/L。此化合物对蜜蜂的急性毒性为中等(48小时，LD50=2.22μg/成虫)，而对斑马鱼的急性毒性较低(LC50: 42.4mg/L)。
T37692	Piericidin B
	Piericidin B is a bacterial metabolite that has been found inS. mobaraensisand has insecticidal and antimicrobial activities.1,2,3It inhibits NADH oxidase activity in isolated bovine heart mitochondria and inhibits respiration in isolated rat liver mitochondria and isolated cockroach (P. americana) muscle mitochondria.2,3Topical application of piericidin B (4 μg/insect) induces mortality in 87.5% of houseflies (M. domestica).1It induces 93.3, 100, and 100% mortality in rice stem borer (C. simple...
T35902	Milbemycin A4 oxime
	Milbemycin A4 oxime is a derivative of milbemycin A4 and a component of milbemycin oxime , compounds that both have insecticidal and nematocidal activity. Milbemycin A4 oxime (0.05 mg/kg) reduces the number of microfilariae of the heartworm D. immitis in naturally infested dogs. It inhibits the growth of clinical isolates of C. glabrata with MIC80 values ranging from 16 to greater than 32 μg/ml. Milbemycin A4 oxime (2.5 μg/ml) blocks efflux of fluconazole from a clinical isolate of C. glabrata, ...
T37052	Tetranactin
	Tetranactin is a macrotetrolide and a monovalent cation ionophore that has been found in S. aureus and has antibacterial, insecticidal, and mitogenic activities. It exhibits an equilibrium permeability ratio 1,000-fold greater for lithium than sodium or cesium ions accross bilayer membranes at low voltages. Tetranactin inhibits the growth of Gram-positive bacteria and C. miyabeanus and R. solani fungi when used at concentrations less than 0.9 μg/ml. Tetranactin (0.5-1.5 μg per insect) dose-depen...
T37498	Antimycin A4
	Antimycin A4 is an active component of the antimycin A antibiotic complex that is more polar than antimycin A1 , antimycin A2 , and antimycin A3 . Antimycin A4 inhibits ATP-citrate lyase with a Ki value of 64.8 μM. The antimycin A complex is a mixture of antimycins A1, A2, A3, and A4 that demonstrates antifungal, insecticidal, nematocidal, and piscicidal properties. It blocks mitochondrial respiration and can deplete cellular levels of ATP via inhibition of complex III of the mitochondrial elect...

化合物

Insecticidal agent 364

Cat.No: T67914

Target: mTOR, Autophagy

Insecticidal agent 6

Cat.No: T82064

Target: Parasite

Insecticidal agent 3

Cat.No: T82065

Insecticidal agent 1

Cat.No: T82066

Insecticidal agent 2

Cat.No: T79122

Target: Parasite

Insecticidal agent 4

Cat.No: T79762

Dodecamethylpentasiloxane

Cat.No: T38845

Target: Parasite

Cat.No: T0776

Synonym: ENT 38,吩噻嗪

Target: Dopamine Receptor, Antibacterial, Antibiotic, Antifungal

Cat.No: T5836

Synonym: 依普菌素,MK-397

Target: Parasite

Epsilon-momfluorothrin

Cat.No: T13683

Synonym: Momfluorothrin, (Z,1R,3R)-

Target: Others

Cat.No: T12987

Synonym: BAJ-2740,螺螨酯

Target: Parasite

Cat.No: T21686

Synonym: CD-1530,CD1530

Target: Retinoid Receptor

Cat.No: T19829

Synonym: Pylon,AC 303630,Pirate,AC-303630,AC303630,虫螨腈

Target: Others

Cat.No: T63059

Target: Antibiotic

Cat.No: T30965

Synonym: Clavamin

Cat.No: T20507

Synonym: NSC 12443,NSC-12443,NSC12443

Cat.No: T37673

Cat.No: T20651

Synonym: NSC 191025,NSC-191025,NC5016,NC 5016,Lovozal,NC-5016

Cat.No: T20658

Cartap hydrochloride

Cat.No: T20195

Synonym: Caldan,Cartap HCl,Cartap monohydrochloride,Dihydronereistoxin dicarbamate

Cat.No: T62069

Cat.No: T38053

Cat.No: T39255

Synonym: beta-Cyfluthrin,β-Cyfluthrin

Cat.No: T25416

Synonym: Evercide 2362

Cat.No: T74113

Cat.No: T32849

Cat.No: T82356

Cat.No: T82355

Cat.No: T62122

Cat.No: T81620

Antifungal agent 77

Cat.No: T83068

Cat.No: T35909

(R)-Dinotefuran

Cat.No: T75301

Cat.No: T35771

Loxosceles Bergeri Venom

Cat.No: T75595

Loxosceles Pilosa Venom

Cat.No: T75596

Loxosceles Spiniceps Venom

Cat.No: T75597

GABA receptor Antagonist 1

Cat.No: T82357

Target: GABA Receptor

Cat.No: T37692

Milbemycin A4 oxime

Cat.No: T35902

Cat.No: T37052

Cat.No: T37498

Cat. No.	Product Name	Target	Signaling Pathways
TN1482	Chamaechromone	P450; HBV	Metabolism; Microbiology/Virology
	Chamaechromone 是从 Stellera chamaejasme L. 的根中分离出来的天然产物。 Chamaechromone 具有抗 HBV 和杀虫活性。
T8256	piperitone 胡椒酮,3甲基-6-(1-甲基乙基)-2-环己烯-1-酮	Others	Others
	Piperitone 是强大的驱虫剂和抗食欲剂。它对 Cymbopogon schoenanthus(C. schoenanthus) 成虫、新产卵和新生幼虫有很大的毒性。
T6569	Mimosine Leucenine,NSC 69188,含羞草素,Leucenol,L-Mimosine	Others	Others
	Mimosine (Leucenol) 是一种酪氨酸类似物，具有抗癌和抗炎等活性。它可通过其强大的铁结合活性作为抗氧化剂，是一种 Fe(III) 螯合剂。它作用于人类白血病细胞，通过金属离子螯合、线粒体激活和诱导活性氧产生来诱导细胞凋亡。
T8193	α-Thujone Thujone,ALPHA-(-)-THUJONE,α-侧柏酮,(-)-α-侧柏酮	Apoptosis; Reactive Oxygen Species; GABA Receptor; AChR; Parasite; Autophagy	Apoptosis; Autophagy; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience; NF-κB
	α-Thujone 是一种从西方金钟柏精油中分离出来的单萜，可穿透血脑屏障。它是 GABAA 受体的可逆调节剂，在抑制 GABA 诱导的电流时，它的 IC50为 21 μM。它诱导 ROS 依赖性细胞毒性，还诱导细胞凋亡和自噬。它具有抗伤害，抗肿瘤、杀虫和驱虫活性。
Fr12275	7-Methoxy-1-tetralone	Others	Others
	7-Methoxy-1-tetralone 可能具有杀虫活性。
TN1087	Deoxypodophyllotoxin 脱氧鬼臼毒素,去氧鬼臼毒素	Apoptosis; Microtubule Associated; Autophagy	Apoptosis; Autophagy; Cytoskeletal Signaling
	Deoxypodophyllotoxin 是从桃儿七根茎分离的一种木酚素，是鬼臼毒素衍生物，具有抗有丝分裂和抗病毒特性。它是血管生成抑制剂，作为靶向微管药物，在肿瘤学中具有重大影响。它引起 DRG 神经元细胞内 Ca2+浓度增加，诱导细胞自噬和凋亡。
T21130	Precocene II 早熟素Ⅱ,AI3-36847,Ageratochromene,BRN 0160683	Others	Others
	Precocene II (Ageratochromene) 是一种抗异体激素化合物，可抑制保幼激素的生物合成。 Precocene II 具有杀虫、抗真菌、抗菌和抗氧化活性。
T7442	4-Isopropylbenzyl Alcohol Cuminic alcohol,4-甲氧基苯甲醇,4-异丙基苯甲醇,Cuminyl alcohol,Cumic alcohol	Others	Others
	4-Isopropylbenzyl Alcohol (Cuminic alcohol) 提取于金花茶 (Camellia nitidissima) 叶和花的精油。其中C.nitidissima 具有多种生物活性，例如抗氧化，抗癌活性，细胞毒性，以及抑制晚期糖基化终产物的形成。
T36473	trans-Nerolidol
	trans-Nerolidol is a sesquiterpene that has been found in various plants, includingC. sativa, and has diverse biological activities, including antimicrobial, antioxidant, anticancer, and insecticidal properties.1,2,3,4In a disc assay,trans-nerolidol inhibits the growth ofS. aureus,B. subtilis,E. coli, andS. cerevisiaewith zones of inhibition measuring 10, 9, 10, and 4 mm, respectively.2It reduces viability of CaCo-2 adenocarcinoma cells with an IC50value of 28.7 mg/L and reduces production of re...
T13626	Cottonseed oil	Others	Others
	Cottonseed oil 是一种提取自棉花种子中的食用油，是一种植物油中杀虫能力极强的油。
T7224	Anabasine (+)-假木贼碱,硫苯咪唑砜,(S)-Anabasine,(-)-Anabasine	AChR	Neuroscience
	Anabasine ((S)-Anabasine) 是一种从烟草中提取的生物碱。Anabasine 是一种烟碱乙酰胆碱受体的全激动剂 (nAChRs)，具有杀虫活性。Anabasine 促使内源表达人肌型 nAChRs 的 TE671 细胞去极化。
TN6110	4,5-Dihydropiperlonguminine 二氢荜茇明宁碱,Dihydropiperlonguminine	Parasite	Microbiology/Virology
	4,5-Dihydropiperlonguminine (Dihydropiperlonguminine) 是一种从 Piper tuberculatum Jacq 的种子中分离出来的小分子化合物，具有杀虫和潜在的镇痛活性。
T5S1054	Wilforgine 雷公藤晋碱,雷公藤精碱	Others	Others
	Wilforgine 是一种具有生物活性的倍半萜烯生物碱，存在于Tripterygium wilfordiiHook. F 中。它能诱导分离出丝状体幼虫肌肉的微结构和超微结构变化，其作用部位被认为是肌肉系统中的钙受体或通道。
T6S0071	Fraxinellone	HIF/HIF Prolyl-Hydroxylase; STAT; PD-1/PD-L1	Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Metabolism; Stem Cells
	Fraxinellone 是从白鲜的根皮中分离出来的一种天然产物，是PD-L1抑制剂，可抑制HIF-1α蛋白质合成。它通过靶向 PD-L1，有用于癌症免疫的潜力。
TN5166	Trans-Methylisoeugenol	Parasite; GST	Microbiology/Virology; oxidation-reduction
	Trans-Methylisoeugenol 是从 Acorus calamus L 中分离得到的具有杀虫活性的化合物。它是一种天然食用香料，具有抗焦虑和抗抑郁等特性，可对谷胱甘肽 S-转移酶（GSTs）产生中度可逆性抑制作用（对人类 GSTs 的抑制浓度为 0.2 至 5.4 毫摩尔，对大鼠 GSTs 的抑制浓度为 0.4 至 4.9 毫摩尔）。
T6S1049	Wilforine	ATPase	Membrane transporter/Ion channel
	Wilforine 是一倍半萜吡啶化合物，T. wilfordii 植物中的重要生物活性化合物，可有效治疗特发性肺纤维化。它具有抗炎和杀虫活性。
T3S2259	Methyl eugenol 4-allylveratrole,eugenyl methyl ether,O-methyleugenol,Eugenol Methyl ether,丁香酚甲醚,丁子香酚甲醚	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	Methyl eugenol (4-allylveratrole) 是一种苯丙类化合物，存在于植物叶子、果实、根茎中，当植物相应的部位因食草动物进食而受损时，就会释放。它可用于消灭雄性东方果蝇。
TN3700	Corianin	Others	Others
	Corianin and coriatin demonstrate synergistic effect to insecticidal activity of tutin againstarmyworm.
T4S0818	Chasmanine
	Chasmanine, hypaconitine, and deoxyaconitine are anti-inflammatory pharmacodynamic components in Heishunpian (HSP) with positive relations with HSP efficacy. Chasmanine has insecticidal activities against larvae of Bradysia odoriphaga Yan et Zhang.
TN1639	Euonymine Evonine,卫矛碱	Others	Others
	Evonine shows insecticidal activity against Mythimna separata, the LC50 value of 23.23 mg /mL.
TN1357	Acetylepipodophyllotoxin	Others	Others
	Acetylepipodophyllotoxin has insecticidal activity.
TN4595	Murraxocin	Others	Others
	Murraxocin is an insecticidal coumarin.
TN2952	3'-Hydroxyrocaglamide	Others	Others
	3'-Hydroxyrocaglamide has insecticidal activity.
TN2962	3'-Methoxyrocaglamide	Others	Others
	C-3'-Methoxyrocaglamide has insecticidal activity.
TN2505	1,5-Diphenylpentan-1-one	AChR	Neuroscience
	1,5-Diphenylpentan-1-one shows poor insecticidal and acetylcholinesterase inhibitory activities.
TN3781	Deacetylnimbin	Others	Others
	Deacetylnimbin shows significant insecticidal activity to Plutella xylostlla L.and Piers rapae L.
TN3701	Coriatin	Others	Others
	Coriatin and corianin demonstrate synergistic effect to insecticidal activity of tutin againstarmyworm.
TN5551	Allamandicin
	Allamandicin shows antifeedant and insecticidal activities against fifth instar larvae of Pieris rapae larvae , the AFC50 value is 0.045 mg/mL after 48 hours.
TN2053	Periplocoside N	Others	Others
	Periplocoside N possesses insecticidal activities against the red imported fire ant.
TN6564	Palustrol
	Palustrol exhibits acaricidal, insecticidal, 'pesticidal' and/or arthropod repellent properties, may be useful sources of chemicals for the control of arthropods of medical, veterinary or agricultural importance.
TN1750	Huzhangoside D	Others	Others
	Huzhangoside D shows insecticidal activities against termite (Coptotermis homii), the LC50 of 0.2 mg/mL.
TL0012	Shyobunone	Others	Others
	Shyobunone and isoshyobunone have insecticidal and repellant activity, they exhibit strong contact toxicity against Lasioderma serricorne (LS adults with LD50 values of 20.24 and 24.19 ug/adult, respectively; they are strongly repellent against Tribolium
TN3329	9-Oxoageraphorone	Others	Others
	9-Oxoageraphorone has strong acaricidal activity against P. cuniculi in vitro, it also exhibits high insecticidal effects.
T82754	Celangulatin D
	Celangulatin D (Compound 2)，一种从南蛇藤根皮中分离出的倍半萜多元醇酯类化合物，具备对粘虫的显著杀虫活性。该化合物亦适用于杀虫剂和抗肿瘤研究领域。
TN3626	Cerbinal	Antifection	Microbiology/Virology
	Cerbinal 是一种天然化合物，来源于非洲非洲菊的草本植物。它具有杀虫活性，是一种潜在的新型害虫防治剂。
TN5091	Tagitinin A	PPAR; Antifection	DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	Tagitinin A is a plant insecticidal compound, it has phytotoxic activity, it shows significant inhibition of wheat coleoptile growth, seed germination, and the growth of STS and weeds. Tagitinin A is also a PPARα/γ dual agonist , it exerts anti-diabetic e
TN3838	Desmethylrocaglamide	Others	Others
	Desmethylrocaglamide is a novel inducer of cellular differentiation using HL-60 promyelocytic cells, it may be a drug for the prevention and therapy of cancer. It also has insecticidal activity.
TN4694	Odoratone	Others	Others
	Odoratone shows insecticidal activities, it shows mortality on fourth instar larvae of mosquitoes (Anopheles stephensi) with LC(50) values of 154 ppm. Odoratone exhibits strong antifeedant activity against Pieris brassicae.
T81941	Leocarpinolide F
	Leocarpinolide F，一天然提取自Siegesbeckia orientalis的类倍半萜烯。
TN4040	Eupatoriochromene	Antifection	Microbiology/Virology
	Eupatoriochromene retard seed germination , reduced radicle and hypocotyl growth of weed and crop plant seedlings and increased adventitious root formation of mung bean cuttings. Eupatoriochromene has insecticidal activity, it exhibits toxicity againstCul
T14368	Azadirachtin B	Others	Others
	Azadirachtin B, a limonoid derived from the seed kernels of Azadirachta indica, exhibits a broad spectrum of biochemical activities, including insecticidal, nematocidal, anticancer, anti-inflammatory, antiviral, and osteogenic effects. It is effective against the Epstein-Barr virus early antigen (EBV-EA), enhances alkaline phosphatase (ALP) activity, and promotes osteoblast differentiation[1][2][3].
T75542	Celangulatin C
	Celangulatin C 是一种杀虫的倍半萜烯多元醇酯，可从 Pseudolarix kaempferi 的根皮中分离得到。Celangulatin C 对Mythimna separata 显示LD50为 280.4 μg/mL。
T11009	Destruxin B	Others	Others
	Destruxin B is a cyclic peptide with insecticidal and anticancer activity isolated from the insect pathogenic fungus Metarhizium isopliae. Destruxin B induces apoptosis of human non-small cell lung cancer cells through the Bcl-2 family-dependent mitochond
T35908	Paraherquamide E
	Paraherquamide E is a fungal metabolite originally isolated from P. charlesii with anthelmintic and insecticidal activities. It is lethal to C. elegans (LD50 = 6 μg/ml). Paraherquamide E is also lethal to O. fasciatus (LD50 = 0.089 μg/nymph). Oral administration of paraherquamide E (0.5-4 mg/kg) reduces T. colubriformis fecal egg count in gerbils.
T82487	Ejaponine A
	Ejaponine A（化合物1）为源于日本卫矛的杀虫倍半萜酯。该化合物展现出强效针对粘虫的活性（LD50为89.2 μg/g），在相关杀粘虫机制研究中得到应用。
TN4623	Nagilactone C	Antifection	Microbiology/Virology
	Nagilactone C and phyllanthoside are novel protein synthesis inhibitors, they are specific for the eukaryotic translation apparatus, function in vivo and in vitro, and interfere with translation elongation. Nagilactone C shows high insecticidal activity against second-instar nymphs of Eocanthecona furcellata. Nagilactone C possesses potent antiproliferative activity against human fibrosarcoma and murine colon carcinoma tumor cell lines exhibiting ED50 values of 2.3 and 1.2 microg/ml, respectivel...
T37690	Phenylpyropene A
	Phenylpyropene A is a fungal metabolite originally isolated from P. griseofulvum that has enzyme inhibitory and insecticidal activities.1,2,3 It inhibits acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 0.8 μM).1 Phenylpyropene A inhibits diacylglycerol acyltransferase (DGAT) in rat liver microsomes (IC50 = 78.7 μM). It induces mortality in 100% of M. persicae when used at a concentration of 5 ppm.3 \|1. Kwon, O.E., Rho, M.C., Song, H.Y., et al. Phenylpyropene A and B, new inhibitors of ...
TN3616	Cedrelone	Apoptosis; MMP; Antifection	Apoptosis; Microbiology/Virology; Proteases/Proteasome
	Cedrelone 是一种柠檬苦素类化合物，是一种吩嗪生物合成样结构域蛋白 (PBLD) 激活剂。Cedrelone 可诱导癌细胞凋亡 (apoptosis)。Cedrelone 是一种非常有效的细胞凋亡诱导剂，它能导致细胞周期停止。Cedrelone 具有杀虫活性，可抑制 P. saucia 的箭毒生长，并可抑制乳草蝽（Oncopeltus fasciatus）的蜕皮。Cedrelone具有抗肿瘤作用，对SMMC-7721、A-549、MCF-7 和 SW480 等癌细胞株具有显著的细胞毒性。
T79990	Notrilobolide	Parasite	Microbiology/Virology
	Notrilobolide 是一种从甘薯中分离出的生物碱，具杀虫特性。对赤拟谷盗（Tribolium castaneum）等害虫幼虫发育产生抑制效果，主要通过限制其繁殖能力来干扰昆虫消化与繁殖过程。
T75543	Angulatin G
	Angulatin G (Celangulatin E) 是一种具有 β-二氢琼脂糖呋喃倍半萜骨架的杀虫倍半萜多元醇酯，可从Celastrusangulatus 根皮中分离得到。 Angulatin G 对Mythimna separata 显示LD50为 1656.4 μg/mL。
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天然产物

Cat.No: TN1482

Target: P450, HBV

Cat.No: T8256

Synonym: 胡椒酮,3甲基-6-(1-甲基乙基)-2-环己烯-1-酮

Target: Others

Cat.No: T6569

Synonym: Leucenine,NSC 69188,含羞草素,Leucenol,L-Mimosine

Target: Others

Cat.No: T8193

Synonym: Thujone,ALPHA-(-)-THUJONE,α-侧柏酮,(-)-α-侧柏酮

Target: Apoptosis, Reactive Oxygen Species, GABA Receptor, AChR, Parasite, Autophagy

7-Methoxy-1-tetralone

Cat.No: Fr12275

Target: Others

Deoxypodophyllotoxin

Cat.No: TN1087

Synonym: 脱氧鬼臼毒素,去氧鬼臼毒素

Target: Apoptosis, Microtubule Associated, Autophagy

Cat.No: T21130

Synonym: 早熟素Ⅱ,AI3-36847,Ageratochromene,BRN 0160683

Target: Others

4-Isopropylbenzyl Alcohol

Cat.No: T7442

Synonym: Cuminic alcohol,4-甲氧基苯甲醇,4-异丙基苯甲醇,Cuminyl alcohol,Cumic alcohol

Target: Others

trans-Nerolidol

Cat.No: T36473

Cat.No: T13626

Target: Others

Cat.No: T7224

Synonym: (+)-假木贼碱,硫苯咪唑砜,(S)-Anabasine,(-)-Anabasine

Target: AChR

4,5-Dihydropiperlonguminine

Cat.No: TN6110

Synonym: 二氢荜茇明宁碱,Dihydropiperlonguminine

Target: Parasite

Cat.No: T5S1054

Synonym: 雷公藤晋碱,雷公藤精碱

Target: Others

Cat.No: T6S0071

Target: HIF/HIF Prolyl-Hydroxylase, STAT, PD-1/PD-L1

Trans-Methylisoeugenol

Cat.No: TN5166

Target: Parasite, GST

Cat.No: T6S1049

Target: ATPase

Cat.No: T3S2259

Synonym: 4-allylveratrole,eugenyl methyl ether,O-methyleugenol,Eugenol Methyl ether,丁香酚甲醚,丁子香酚甲醚

Target: GABA Receptor

Cat.No: TN3700

Target: Others

Cat.No: T4S0818

Cat.No: TN1639

Synonym: Evonine,卫矛碱

Target: Others

Acetylepipodophyllotoxin

Cat.No: TN1357

Target: Others

Cat.No: TN4595

Target: Others

3'-Hydroxyrocaglamide

Cat.No: TN2952

Target: Others

3'-Methoxyrocaglamide

Cat.No: TN2962

Target: Others

1,5-Diphenylpentan-1-one

Cat.No: TN2505

Target: AChR

Cat.No: TN3781

Target: Others

Cat.No: TN3701

Target: Others

Cat.No: TN5551

Periplocoside N

Cat.No: TN2053

Target: Others

Cat.No: TN6564

Cat.No: TN1750

Target: Others

Cat.No: TL0012

Target: Others

9-Oxoageraphorone

Cat.No: TN3329

Target: Others

Cat.No: T82754

Cat.No: TN3626

Target: Antifection

Cat.No: TN5091

Target: PPAR, Antifection

Desmethylrocaglamide

Cat.No: TN3838

Target: Others

Cat.No: TN4694

Target: Others

Leocarpinolide F

Cat.No: T81941

Eupatoriochromene

Cat.No: TN4040

Target: Antifection

Cat.No: T14368

Target: Others

Cat.No: T75542

Cat.No: T11009

Target: Others

Paraherquamide E

Cat.No: T35908

Cat.No: T82487

Cat.No: TN4623

Target: Antifection

Phenylpyropene A

Cat.No: T37690

Cat.No: TN3616

Target: Apoptosis, MMP, Antifection

Cat.No: T79990

Target: Parasite

Cat.No: T75543

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