VEGFR

VEGF receptors are receptors for vascular endothelial growth factor (VEGF). There are three main subtypes of VEGFR, numbered 1, 2 and 3. Also, they may be membrane-bound (mbVEGFR) or soluble (sVEGFR), depending on alternative splicing.

Cat. No.	Product Name	CAS No.	Purity
T80873	VEGFR2/HDAC1-IN-1 化合物 VEGFR2/HDAC1-IN-1		98%
T80873	VEGFR2/HDAC1-IN-1（compound 13）是一款有效的VEGFR-2和HDAC双重抑制剂，其IC50值分别为57.83 nM 和9.82 nM 。该化合物能够阻滞细胞周期于S期及G2期，并能诱导HeLa细胞发生凋亡，同时具有抗血管生成的特性。
T80874	VEGFR-2/c-Met-IN-1 化合物 VEGFR-2/c-Met-IN-1		98%
T80874	VEGFR-2/c-Met-IN-1为VEGFR-2及c-Met的双重抑制剂，IC50值为138 nM和74 nM，显示出抗肿瘤活性。
T81054	T-1-MCPAB 化合物 T-1-MCPAB		98%
T81054	T-1-MCPAB为一种高效VEGFR-2抑制剂（IC50=0.135 µM），其显著抑制MCF7细胞迁移，适用于癌症相关研究。
T81125	Sotiburafusp alfa 化合物 Sotiburafusp alfa	2637466-37-4	98%
T81125	Sotiburafusp alfa为一双特异性融合蛋白，由人源化VEGFR-1胞外结构域片段经101GGSGGSGGSGGSGGS115肽链与人源化IgG1-kappa 抗PD-L1重链变体L352>A、L353>A的N端(116-564)连接而成。该化合物同时具备血管生成抑制作用。
TN3587	Capillarisin 化合物 TN3587	56365-38-9	98%
TN3587	Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cell...
T13156	TG 100572 化合物 T13156	867334-05-2	98%
T13156	TG 100572 is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2 ...
TN1867	Licoricidin 甘草西定	30508-27-1	98%
TN1867	Licoricidin, is a potent anti-metastatic agent, which can markedly inhibit the metastatic and invasive capacity of malignant prostate cancer cells.
TQ0080	SU14813 maleate SU14813马来酸盐	849643-15-8	98%
TQ0080	SU14813 maleate is an inhibitor of multi-targeted receptor tyrosine kinases (IC50s: 2, 50, 4, 15 nM for VEGFR1, VEGFR2, PDGFRβ, and KIT).
TN4913	Riddelline 化合物 TN4913	23246-96-0	98%
TN4913	Riddelline is a potent genotoxic agent in vitro and induces significant elevations in unscheduled DNA synthesis and S-phase synthesis in rat liver.
T6936	PF-03814735 化合物PF-03814735	942487-16-3	98%
T6936	PF-03814735 是一种新型、有效和可逆的极光激酶 A 和 B 抑制剂，IC50值分别为0.8和5 nM。
TN1095	Ginsenoside Rk2 人参皂苷RK2	364779-14-6	98%
TN1095	Ginsenoside Rk1 has anti-tumor, and anti-platelet aggregation activities.
TMA1743	Ergosterol peroxide 过氧麦角甾醇	2061-64-5	98%
TMA1743	Ergosterol peroxide is an inhibitor of osteoclast differentiation, which has antiviral, trypanocidal, antitumor, and antiangiogenic actions, it can stimulate Fox...
TN4748	Penduletin 化合物 TN4748	569-80-2	98%
TN4748	Penduletin has anti-inflammatory,anti-tumor cells, and anti-bacterical activities,it inhibits growth of the Gram-negative pathogen neisseria gonorrhoeae. Pendule...
TN4603	Myricanol 化合物 TN4603	33606-81-4	98%
TN4603	Myricanol can elicit growth inhibitory and cytotoxic effects on lung cancer cells, it can significantly decelerate tumor growth in vivo by inducing apoptosis.
T74000	CP-547632 TFA 化合物 CP-547632 TFA	2805804-54-8	98%
T74000	CP-547632 TFA是一款口服效果显著的ATP競爭性抑制劑，针对VEGFR-2和FGF激酶具有高度选择性，IC50值分别为11 nM和9 nM。该化合物相较于EGFR和PDGFRβ，对VEGFR2和bFGF展现出更高的选择性，优于相关的酪氨酸激酶（TKs）。CP-547632 TFA还显示了显著的抗肿瘤活性。
T13157L	TG 100801 Hydrochloride 化合物 T13157L	1018069-81-2	98%
T13157L	TG 100801 Hydrochloride is a prodrug to treat age-related macular degeneration. TG 100572 is a inhibitor of multi-targeted kinase(IC50s of 2, 7, 2, 16, 13, 5, 0....
TN5250	Vomifoliol 化合物 TN5250	23526-45-6	98%
TN5250	Vomifoliol is most likely the immediate precursor of dehydrovomifoliol, because of the organism converted abscisic acid (ABA), to dehydrovomifoliol as the major ...
T13039	Sunitinib-d10 化合物 T13039	1126721-82-1	98%
T13039	Sunitinib D10 is a deuterium labeled Sunitinib. Sunitinib is a inhibitor of multi-targeted receptor tyrosine kinase(IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ...
TN5050	Sprengerinin C 化合物 TN5050	88861-91-0	98%
TN5050	Sprengerinin C exerts anti-tumorigenic effects in hepatocellular carcinoma via inhibition of proliferation and angiogenesis and induction of apoptosis, it can st...
TN5100	Taspine 化合物 TN5100	602-07-3	98%
TN5100	Taspine shows antitumor activity by modulating the EGFR signaling pathway of Erk1/2 and Akt in vitro and in vivo, it can inhibit growth and induce apoptosis of H...