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TargetMol产品目录中 "

VP16

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  • 抑制剂&激动剂
    3
    TargetMol | Inhibitors_Agonists
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    TargetMol | Recombinant_Protein
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    TargetMol | Natural_Products
  • Etoposide
    依托泊苷, 依托泊甙, VP-16-213, VP-16
    T013233419-42-0
    Etoposide (VP-16-213) 是一种拓扑异构酶 II 的抑制剂,通过与拓扑异构酶 II 和 DNA 形成复合物来抑制 DNA 合成 (IC50=60.3 μM)。Etoposide 具有抗肿瘤活性,可以诱导细胞凋亡、自噬。
    • ¥ 287
    现货
    规格
    数量
    TargetMol | Citations 客户已引用
  • Etoposide Phosphate
    磷酸依托泊苷, Eposin Etopophos Vepesid VP16
    T21303117091-64-2
    Etoposide phosphate is a phosphate salt of Etoposide, which binds to the enzyme topoisomerase II, then induces double-strand DNA breaks and inhibits DNA repair, leading to decreased DNA synthesis and tumor cell proliferation.
    • ¥ 397
    5日内发货
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  • Ki23057
    T69162516523-31-2
    Ki23057 is a a FGFR2 inhibitor, which enhances the chemosensitivity of drug-resistant gastric cancer cell lines when used in combination with chemotherapeutic drugs. Ki23057 might be therapeutically promising for treating drug-resistant gastric cancer cells, especially when used in combination with SN38, PTX, or VP16. The apoptosis process might be the main mechanism underlying the synergistic effect of these combinations. The ERCC1 and p53 genes may play an integral role in the synergism between Ki23057 and chemotherapeutic agents in drug-resistant cell lines. (source: Cancer Lett. 2011 Aug 1;307(1):47-52).
    • ¥ 10600
    6-8周
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