Azido-PEG1-NHSester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Azido-PEG8-C1-NHSester is a polyethylene glycol (PEG)-based linker, specifically designed for the synthesis of proteolysis targeting chimeras (PROTACs)[1].
Azido-PEG6-NHSester is a cleavable 6 unit polyethylene glycol (PEG) linker, commonly employed in the synthesis of antibody-drug conjugates (ADCs)[1]. Additionally, it serves as a PEG- and alkyl ether based linker for the synthesis of proteolysis targeting chimeras (PROTACs)[2].
Azido-PEG3-SS-NHS is a three-unit polyethylene glycol (PEG) linker functionalized with an azide group, a cleavable disulfide bond, and an N-hydroxysuccinimide ester. It is primarily employed in the synthesis of antibody-drug conjugates (ADCs) [1].
Azido-PEG8-NHSester is an 8 unit PEG linker with cleavable properties, commonly employed in the synthesis of antibody-drug conjugates (ADCs)[1]. This compound also serves as a PEG- and Alkyl ether-based PROTAC linker, enabling its utilization in the synthesis of PROTACs[2].
N-(Azido-PEG4)-N-Boc-PEG4-NHSester is a PEG-based PROTAC linker featuring a terminal azide group. It is commonly employed in the synthesis of PROTACs[1].