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纤维生长因子受体

纤维生长因子受体

纤维生长因子受体 (Fibroblast Growth Factor Receptors, FGFRs) 是与纤维生长因子 (Fibroblast Growth Factor ,FGF) 蛋白家族成员结合的受体。FGFR 由一个由三个免疫球蛋白样结构域组成的细胞外配体结构域、一个跨膜螺旋结构域和一个具有酪氨酸激酶活性的细胞内结构域组成。FGF/FGFR信号通路与多种癌症有关。目前有作用于所有 FGFR1-4 和其他蛋白质的非选择性 FGFR 抑制剂,以及作用于部分/全部 FGFR1-4 的一些选择性 FGFR 抑制剂,例如AZD4547、BGJ398、JNJ42756493和PD173074。

TargetMol Recombinant Protein
1 2 3 4
Species
Cynomolgus (3)
Human (50)
Mouse (11)
Rat (2)
Rhesus (5)
Rhesus macaque (1)
Expression System
Baculovirus-Insect Cells (3)
HEK293 (63)
Human Cells (5)
Tag
AVI (1)
C-6His (1)
C-Avi (2)
C-Fc (4)
C-His (4)
C-His-Avi (20)
GST (3)
His (27)
hFc (16)
Cat. No. Product Name / Synonyms Species Expression System
TMPJ-00388 FGFR2IIIc Protein, Human, Recombinant (hFc)
FGFR2IIIc Protein, Human, Recombinant (hFc)
Human Human Cells
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and througho...
TMPJ-00389 FGFR2 alpha (IIIc) Protein, Human, Recombinant (hFc)
FGFR2 alpha (IIIc) Protein, Human, Recombinant (hFc)
Human Human Cells
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and througho...
TMPJ-00390 FGFR2IIIb Protein, Human, Recombinant (hFc)
FGFR2IIIb Protein, Human, Recombinant (hFc)
Human Human Cells
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and througho...
TMPJ-00391 FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc)
FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc)
Human Human Cells
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and througho...
TMPJ-01224 FGFRL1 Protein, Human, Recombinant (His)
FGFRL1 Protein, Human, Recombinant (His)
Human Human Cells
Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) is a single-pass type I membrane protein that belongs to the FGF receptor family. The mature human FGFRL1 consi...
TMPK-00378 FGFR4 beta Protein, Human, Recombinant (His & Avi)
FGFR4 beta Protein, Human, Recombinant (His & Avi)
Human HEK293
Fibroblast growth factor receptor 4 (FGF R4), also known as CD334, is a 110 kDa glycosylated transmembrane receptor tyrosine kinase.Tyrosine-protein kinase that ...
TMPK-00379 FGFR4 Protein, Human, Recombinant (His & Avi)
FGFR4 Protein, Human, Recombinant (His & Avi)
Human HEK293
Fibroblast growth factor receptor 4 (FGF R4), also known as CD334, is a 110 kDa glycosylated transmembrane receptor tyrosine kinase.Tyrosine-protein kinase that ...
TMPK-00380 FGFR4 beta Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR4 beta Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293
Fibroblast growth factor receptor 4 (FGF R4), also known as CD334, is a 110 kDa glycosylated transmembrane receptor tyrosine kinase.Tyrosine-protein kinase that ...
TMPK-00381 FGFR4 Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR4 Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293
Fibroblast growth factor receptor 4 (FGF R4), also known as CD334, is a 110 kDa glycosylated transmembrane receptor tyrosine kinase.Tyrosine-protein kinase that ...
TMPK-00384 FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi)
FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi)
Human HEK293
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, thr...
TMPK-00385 FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi)
FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi)
Human HEK293
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, thr...
TMPK-00386 FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, thr...
TMPK-00387 FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, thr...
TMPK-00388 FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi)
FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi)
Human HEK293
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, thr...
TMPK-00389 FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi)
FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi)
Human HEK293
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, thr...
TMPK-00390 FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, thr...
TMPK-00391 FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, thr...
TMPK-00392 FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi)
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi)
Human HEK293
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabo...
TMPK-00393 FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi)
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi)
Human HEK293
Fibroblast growth factors (FGFs) comprise a family of at least eighteen structurally related proteins that are involved in a multitude of physiological and patho...
TMPK-00394 FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabo...
FGFR2IIIc Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00388
Species: Human
Expression System: Human Cells
Tag: C-Fc
FGFR2 alpha (IIIc) Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00389
Species: Human
Expression System: Human Cells
Tag: C-Fc
FGFR2IIIb Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00390
Species: Human
Expression System: Human Cells
Tag: C-Fc
FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc)
Cat.No: TMPJ-00391
Species: Human
Expression System: Human Cells
Tag: C-Fc
FGFRL1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01224
Species: Human
Expression System: Human Cells
Tag: C-6His
FGFR4 beta Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00378
Species: Human
Expression System: HEK293
Tag: C-His-Avi
FGFR4 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00379
Species: Human
Expression System: HEK293
Tag: C-His-Avi
FGFR4 beta Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00380
Species: Human
Expression System: HEK293
Tag: C-His-Avi
FGFR4 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00381
Species: Human
Expression System: HEK293
Tag: C-His-Avi
FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00384
Species: Human
Expression System: HEK293
Tag: C-His-Avi
FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00385
Species: Human
Expression System: HEK293
Tag: C-His-Avi
FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00386
Species: Human
Expression System: HEK293
Tag: C-His-Avi
FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00387
Species: Human
Expression System: HEK293
Tag: C-His-Avi
FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00388
Species: Human
Expression System: HEK293
Tag: C-His-Avi
FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00389
Species: Human
Expression System: HEK293
Tag: C-His-Avi
FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00390
Species: Human
Expression System: HEK293
Tag: C-His-Avi
FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00391
Species: Human
Expression System: HEK293
Tag: C-His-Avi
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00392
Species: Human
Expression System: HEK293
Tag: C-His-Avi
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00393
Species: Human
Expression System: HEK293
Tag: C-His-Avi
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00394
Species: Human
Expression System: HEK293
Tag: C-His-Avi
1 2 3 4
TargetMol Loading
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