Dopamine Receptor

Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system (CNS). Dopamine receptors activate different effectors through not only G-protein coupling, but also signaling through different protein (dopamine receptor-interacting proteins) interactions.

Cat. No.	Product Name	CAS No.	Purity
T13245	UCSF924 化合物 T13245	1434515-70-4	98%
T13245	UCSF924 is a potent and specific agonist of dopamine D4 receptor (DRD4) partial (EC50: 4.2 nM, Ki: 3 nM).
T12288	Odapipam 化合物 T12288	131796-63-9	98%
T12288	Odapipam is a selective and high affinity antagonist of benzazepine dopamine D1 receptor (Kd of 0.18 nM).
T1476L	Pramipexole dihydrochloride 盐酸普拉克索	104632-25-9	98%
T1476L	Pramipexole dihydrochloride could be used to treat Parkinson disease.
T22921	LE 300 化合物LE 300	274694-98-3	98%
T22921	LE 300 是选择性多巴胺 D1 样受体拮抗剂，作用于人多巴胺 D1 和 D5 受体的Kis 分别为 1.9 nM 和 7.5 nM。在大鼠尾动脉实验中，它作用于5-HT2A 受体的pA2 为 8.32。
T10611	Brexpiprazole S-oxide D8 化合物 T10611	2748605-29-8	98%
T10611	Brexpiprazole S-oxide D8 (DM-3411 D8) is a deuterium labeled Brexpiprazole S-oxide. Brexpiprazole S-oxide is a main metabolite of Brexpiprazole. Brexpiprazole is...
T21360	Asenapine 阿塞那平	65576-45-6	98%
T21360	Asenapine (Org 5222) 是5-HT受体、肾上腺素受体、多巴胺受体和组胺受体拮抗剂，具有抗精神病作用，可用于治疗精神分裂症和与双相 1 型障碍相关的躁狂或混合发作。
TQ0175	Dexpramipexole 右旋普拉克索	104632-28-2	98%
TQ0175	Dexpramipexole (KNS-760704, R-(+)-Pramipexole) is a neuroprotective agent and weak non-ergoline dopamine agonist.
TQ0140	Sumanirole maleate 马来酸Sumanirole	179386-44-8	98%
TQ0140	Sumanirole maleate (U-95666E) is a highly selective full agonist of the D2 receptor (ED50: 46 nM).
T7341	Diclofensine (+/-)-双氮奋兴	67165-56-4	98%
T7341	Diclofensine (Ro 8-4650) 是一种高效单胺再摄取抑制剂，在大鼠脑突触体中能够阻断多巴胺 (IC50=0.74 nM)、去甲肾上腺素 (IC50=2.3 nM) 和 5-羟色胺 (IC50=3.7 nM)。
T9540	Phenelzine 苯乙肼	51-71-8	98%
T9540	Phenelzine 是一种抗抑郁和躁狂症药物，是一种单胺氧化酶抑制剂。其抗抑郁作用与烟酰胺相似。可减少脑内儿茶酚胺（去甲肾上腺素、多巴胺、5-羟色胺）的降解，增加儿茶酚胺的含量。，并起到抗抑郁作用。对内源性抑郁症疗效较好，对外源性和反应性抑郁症疗效较差。
T11799L	L-745870 化合物 T11799L	158985-00-3	98%
T11799L	L-745870 is a high-affinity and selective human dopamine D4 receptor antagonist (Ki: 0.43 nM). L-745870 has excellent brain penetration. It considerably weaker D...
T12476	Pimozide-d4 化合物 T12476	1803193-57-8	98%
T12476	Pimozide D4 is a deuterium labeled Pimozide.
T13463L	Dihydrexidine 化合物 T13463L	123039-93-0	98%
T13463L	Dihydrexidine is a full efficacy D1-like dopamine receptor (D1/D5) agonist (IC50: 10 nM for D1 receptor). It also shows potent antiparkinsonian activity.
T13898	SPD-473 citrate 化合物 T13898	161190-26-7	98%
T13898	SPD-473 citrate is an inhibitior of serotonin/dopamine/norepinephrine reuptake.
T10908	CY 208-243 化合物 T10908	100999-26-6	98%
T10908	CY 208-243 is a selective dopamine D1 receptor agonist with anti-Parkinson disease activity.
T12865	SCH-23390 maleate 化合物SCH-23390 maleate	87134-87-0	98%
T12865	SCH-23390 maleate (R-(+)-SCH-23390 maleate) 是多巴胺D1样受体选择性拮抗剂，与D1和D5受体结合的Ki 分别为 0.2 nM 和 0.3 nM。它也是人5-HT2C 受体激动剂，Ki 为 9.3 nM。它与5-HT2和5-HT1C 受体具有高亲和力。它还抑制 G 蛋白偶联的内向...
T13652	Dicarbine 化合物 T13652	17411-19-7	98%
T13652	Double carbene can be used for the study of schizophrenia and alcoholism. It can block dopamine receptors in various parts of the brain and prevent the reduction...
T68023	Tolnapersine 托那哌嗪	70312-00-4	98%
T68023	Tolnapersine 是混合多巴胺激动剂和α-肾上腺素受体拮抗剂。
T10681	Cariprazine D6 化合物 T10681	1308278-67-2	98%
T10681	Cariprazine D6 (RGH-188 D6) is a deuterium-labeled Cariprazine. Cariprazine is an antipsychotic agent (D3 receptors, Ki: 0.085 nM; D2 receptors, Ki: 0.49 nM).
TN1424	Bacopaside X 假马齿苋皂苷 VII	94443-88-6	98%
TN1424	Bacopaside X (9.06 μM) showed binding affinity towards the D1 receptor.