血小板源生长因子受体

血小板源生长因子受体 (Platelet-Derived Growth Factor Receptors, PDGFRs) 是血小板源生长因子（PDGF）家族成员的细胞表面酪氨酸激酶受体。PDGF亚基-A和-B是调节细胞增殖、细胞分化、细胞生长、发育和包括癌症在内的许多疾病的重要因素。PDGF-R有两种形式，α和β，每种形式由不同的基因编码。根据结合的生长因子，PDGF-R 同源或异源二聚化。对 RTKs 诱导的不同信号级联的检查确立了 Ras/MAPK、PI3K和PLCγ通路作为 PDGFR 信号转导的关键下游介质。此外，活性氧依赖性 STAT3 激活已被确定为血管平滑肌细胞中 PDGFR 信号传导的关键下游介质。

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Cat. No.	Product Name / Synonyms	Species	Expression System
TMPK-00419	PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi) PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi)	Human	HEK293
TMPK-00419	Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. Th...
TMPK-00420	PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
TMPK-00420	Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. Th...
TMPK-00421	PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi) PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi)	Human	HEK293
TMPK-00421	PDGF is a major serum mitogen that can exist as a homo or hetero-dimeric protein consisting of disulfide-linked PDGF-A and PDGF-B chains. The PDGF-AA,PDGF-BB and...
TMPK-00422	PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
TMPK-00422	PDGF is a major serum mitogen that can exist as a homo or hetero-dimeric protein consisting of disulfide-linked PDGF-A and PDGF-B chains. The PDGF-AA,PDGF-BB and...
TMPK-00481	PDGF R beta/CD140b Protein, Cynomolgus, Recombinant (His) PDGF R beta/CD140b Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
TMPK-00481	Platelet-derived growth factor receptor (PDGFR) signaling is involved in proliferation and survival in a wide array of cell types.PDGFR-β signalling, via TGF-β s...
TMPK-00943	PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His) PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
TMPK-00943	Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. Th...
TMPK-01050	PDGF R beta/CD140b Protein, Canine, Recombinant (His) PDGF R beta/CD140b Protein, Canine, Recombinant (His)	Canine	HEK293
TMPK-01050	PDGF is a major serum mitogen that can exist as a homo or hetero-dimeric protein consisting of disulfide-linked PDGF-A and PDGF-B chains. The PDGF-AA,PDGF-BB and...
TMPY-00385	PDGFRB Protein, Rhesus, Recombinant (hFc) PDGFRB Protein, Rhesus, Recombinant (hFc)	Rhesus	HEK293
TMPY-00385	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified...
TMPY-00900	PDGFRA Protein, Human, Recombinant (hFc) PDGFRA Protein, Human, Recombinant (hFc)	Human	HEK293
TMPY-00900	PDGFRA, also known as CD140a, together with the structurally homolog protein PDGFRB (CD140b), are cell surface receptors for members of the platelet-derived grow...
TMPY-01207	PDGFRB Protein, Human, Recombinant (His) PDGFRB Protein, Human, Recombinant (His)	Human	HEK293
TMPY-01207	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified...
TMPY-03140	PDGFRB Protein, Rat, Recombinant (His) PDGFRB Protein, Rat, Recombinant (His)	Rat	HEK293
TMPY-03140	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified...
TMPY-03474	PDGFRB Protein, Rat, Recombinant (hFc) PDGFRB Protein, Rat, Recombinant (hFc)	Rat	HEK293
TMPY-03474	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified...
TMPY-03590	PDGFRB Protein, Rhesus, Recombinant (His) PDGFRB Protein, Rhesus, Recombinant (His)	Rhesus	HEK293
TMPY-03590	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified...
TMPY-03825	PDGFRA Protein, Rat, Recombinant (His) PDGFRA Protein, Rat, Recombinant (His)	Rat	HEK293
TMPY-03825	PDGFRA, also known as CD140a, together with the structurally homolog protein PDGFRB (CD140b), are cell surface receptors for members of the platelet-derived grow...
TMPY-03919	PDGFRA Protein, Rat, Recombinant (hFc) PDGFRA Protein, Rat, Recombinant (hFc)	Rat	HEK293
TMPY-03919	PDGFRA, also known as CD140a, together with the structurally homolog protein PDGFRB (CD140b), are cell surface receptors for members of the platelet-derived grow...
TMPY-04937	PDGFRB Protein, Human, Recombinant (His), Biotinylated PDGFRB Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
TMPY-04937	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified...
TMPY-05358	PDGFRB Protein, Human, Recombinant PDGFRB Protein, Human, Recombinant	Human	HEK293
TMPY-05358	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified...
TMPY-05497	PDGFRB Protein, Human, Recombinant (hFc) PDGFRB Protein, Human, Recombinant (hFc)	Human	HEK293
TMPY-05497	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified...
TMPY-05608	PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
TMPY-05608	PDGFRA, also known as CD140a, together with the structurally homolog protein PDGFRB (CD140b), are cell surface receptors for members of the platelet-derived grow...
TMPY-05787	PDGFRA Protein, Mouse, Recombinant (His) PDGFRA Protein, Mouse, Recombinant (His)	Mouse	HEK293
TMPY-05787	PDGFRA, also known as CD140a, together with the structurally homolog protein PDGFRB (CD140b), are cell surface receptors for members of the platelet-derived grow...