Potassium Channel

Potassium Channels. K+ channels are membrane proteins that allow rapid and selective flow of K+ ions across the cell membrane, and thus generate electrical signals in cells. Voltage-gated K+ channels (Kv channels), present in all animal cells, open and close upon changes in the transmembrane potential.

Cat. No.	Product Name	CAS No.	Purity
T80530	Spinoxin 化合物 Spinoxin	752984-66-0	98%
T80530	Spinoxin是一种从Heterometrus spinifer蝎子毒液中提取的神经毒素，由34个氨基酸残基组成，通过4个二硫桥交联。它能有效抑制Kv1.3钾通道（IC50= 63 nM），是研发诊断及治疗自身免疫性疾病和癌症策略时的潜在分子靶点。
TMA0763	Methyl 3,4,5-trimethoxycinnamate 化合物 TMA0763	7560-49-8	98%
TMA0763	Methyl 3,4,5-trimethoxycinnamate may protect the heart from arrhythmias via its inhibitory effect on calcium channel.
TP1852	Myomodulin 肌调蛋白	110570-93-9	98%
TP1852	Myomodulin 是一种存在于软体动物、昆虫和腹足类动物中的神经肽。它存在于两个已确定的海兔神经元中，它们包含肌调节蛋白 A、ARC 运动神经元 B16 和腹部神经元 L10。
TN3319	9-Hydroxycanthin-6-one 化合物 TN3319	138544-91-9	98%
TN3319	9-Hydroxycanthin-6-one might be the active component that contributed to the aphrodisiac effect of E. longifolia by antagonizing the smooth muscle tone of CC as ...
TQ0307	Vernakalant 维那卡兰	794466-70-9	98%
TQ0307	Vernakalant (RSD-1235) is a mixed ion channel blocker.
T14040	4-Hydroxytolbutamide 化合物 T14040	5719-85-7	98%
T14040	4-Hydroxytolbutamide(Hydroxytolbutamide), a metabolite of Tolbutamide, which is metabolized by CYP2C8 and CYP2C9. Tolbutamide is a first generation potassium cha...
TN4697	Odoroside H 化合物 TN4697	18810-25-8	98%
TN4697	Odoroside H has anticancer activities, the cytotoxic effects are induced by the inhibition of the plasma membrane bound Na(+)/K(+)-ATPase.
TN5141	Thevetin B 黄夹甙 B	27127-79-3	98%
TN5141	Thevetin B 是一种强心苷，是Na+-, K+-依赖性腺苷三磷酸酶 (Na+,K+-ATPase) 的抑制剂，来自 Thevetia peruviana。
TN3636	Chlorahololide C 化合物 TN3636	1007859-25-7	98%
TN3636	Chlorahololide C is a potent and selective potassium channel blocker, it exerts potent and selective inhibition on the delayed rectifier (I(K)) K(+) current with...
T16285	Neosolaniol 新茄病镰刀菌烯醇	36519-25-2	98%
T16285	Neosolaniol, a type A trichothecene mycotoxin produced by Fusarium species, strongly induces an anorectic (loss of appetite) response.
TN4322	Isopulegol 化合物 TN4322	7786-67-6	98%
TN4322	Isopulegol presents depressant- and anxiolytic-like effects, it also has anticonvulsant and bioprotective effects against PTZ-induced convulsions are possibly re...
T6827	Endoxifen Z-isomer hydrochloride Z-因多昔芬盐酸盐	1032008-74-4	98%
T6827	Endoxifen Z-isomer hydrochloride (Endoxifen HCl) 是Tamoxifen 最重要的代谢产物, 在表达ERα的乳腺癌细胞中发挥抗雌激素作用, Endoxifen HCl 以浓度依赖的方式抑制hERG, IC50值为1.6μM。
T14189	Almokalant 化合物 T14189	123955-10-2	98%
T14189	Almokalant is a class III antiarrhythmic drug, acts as a potassium channel blocker. And it inhibits a specific component (Ikr) of the time-dependent delayed rect...
T11753	Keto Ziprasidone 化合物 T11753	884305-07-1	98%
T11753	Ziprasidone, an antipsychotic agent, functions as a dual antagonist of 5-HT (serotonin) and dopamine receptors. Keto Ziprasidone represents an impurity found wit...
TN2918	3-Acetoxy-8(17),13E-labdadien-15-oic acid 化合物 TN2918	63399-37-1	98%
TN2918	ent-3-Acetoxy-labda-8(17),13-dien-15-oic acid have vasorelaxant and hypotensive actions, the mechanisms underlying the cardiovascular actions of the labdane invo...
TN1588	Dihydroisotanshinone I 二氢异丹参酮I	20958-18-3	98%
TN1588	Dihydroisotanshinone I has protective action against menadione-induced hepatotoxicity, attributed to its antioxidant properties including the free radical scaven...
TN4303	Isokaempferide 化合物 TN4303	1592-70-7	98%
TN4303	Isokaempferide shows hepatoprotective, antiproliferative, and anti-inflammatory effects, the anti-inflammatory effects can be explained, at least in part, by red...
TMA0805	Lupanine 化合物 TMA0805	550-90-3	98%
TMA0805	Lupanine has a weak sedative effect on the central nervous system, interaction with specific drugs used for treatment of the CNS and for analgesic activity. Lupa...
TN2306	Wilfordine 雷公藤定碱	37239-51-3	98%
TN2306	Wilfordine is an insecticidally active alkaloid, Na+-K+-ATPase may be an acting target of wilfordine against some larvae of insect.
TN1367	Alismol 化合物Alismol	87827-55-2	98%
TN1367	Alismol has antihypertensive action, it decreases cardiac output, heart rate and left ventricular pressure, but it increases coronary flow, it has been used for ...